AIFM3 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	4 studies	30% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of AIFM3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	4414.73	2634 / 2642	83%	8.92	587 / 705
intestine	40%	1574.21	384 / 966	79%	14.70	417 / 527
bladder	24%	108.14	5 / 21	79%	8.47	396 / 504
pancreas	0%	0	0 / 328	69%	1.85	122 / 178
lung	9%	42.51	50 / 578	51%	1.48	591 / 1155
stomach	0%	0	0 / 359	57%	10.55	163 / 286
uterus	0%	0	0 / 170	45%	1.47	206 / 459
eye	0%	0	0 / 0	44%	0.70	35 / 80
esophagus	0%	0	0 / 1445	43%	0.83	79 / 183
spleen	38%	189.00	92 / 241	0%	0	0 / 0
breast	0%	8.60	1 / 459	38%	0.71	420 / 1118
kidney	2%	15.48	2 / 89	30%	0.55	271 / 901
liver	0%	0	0 / 226	28%	0.59	115 / 406
skin	0%	0.21	1 / 1809	26%	0.58	122 / 472
adrenal gland	0%	2.00	1 / 258	17%	0.34	40 / 230
thymus	0%	0.69	1 / 653	17%	0.36	102 / 605
tonsil	0%	0	0 / 0	16%	0.22	7 / 45
prostate	5%	21.84	12 / 245	10%	0.15	50 / 502
ovary	0%	0	0 / 180	12%	0.21	53 / 430
lymph node	0%	0	0 / 0	7%	0.12	2 / 29
peripheral blood	2%	8.32	17 / 929	0%	0	0 / 0
adipose	0%	0.67	2 / 1204	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
blood vessel	0%	0	0 / 1335	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0097194	Biological process	execution phase of apoptosis
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005739	Cellular component	mitochondrion
GO_0005634	Cellular component	nucleus
GO_0051537	Molecular function	2 iron, 2 sulfur cluster binding
GO_0016651	Molecular function	oxidoreductase activity, acting on NAD(P)H
GO_0050660	Molecular function	flavin adenine dinucleotide binding
GO_0046872	Molecular function	metal ion binding

Gene name	AIFM3
Protein name	Apoptosis inducing factor mitochondria associated 3 Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein)
Synonyms	AIFL
Description	FUNCTION: Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. .
Accessions	ENST00000399167.6 [Q96NN9-1] F8WFB6 C9JPU8 ENST00000426113.5 ENST00000683034.1 [Q96NN9-3] ENST00000405089.5 [Q96NN9-2] F8WC30 ENST00000434714.6 ENST00000399163.6 [Q96NN9-3] ENST00000440238.4 [Q96NN9-1] C9K029 ENST00000417515.5 ENST00000441376.6 Q96NN9

AIFM3 report