I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 19% ± 4% | |
| glutamatergic neuron | 3 studies | 26% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 19% ± 4% | |
| glutamatergic neuron | 3 studies | 26% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 1110.14 | 459 / 459 | 100% | 30.95 | 1118 / 1118 |
| ovary | 100% | 936.73 | 180 / 180 | 100% | 21.57 | 430 / 430 |
| esophagus | 100% | 999.93 | 1444 / 1445 | 100% | 25.82 | 183 / 183 |
| stomach | 100% | 819.36 | 358 / 359 | 100% | 26.64 | 286 / 286 |
| pancreas | 100% | 783.17 | 327 / 328 | 100% | 19.83 | 178 / 178 |
| intestine | 100% | 966.35 | 966 / 966 | 100% | 26.82 | 525 / 527 |
| bladder | 100% | 1015.05 | 21 / 21 | 100% | 25.23 | 502 / 504 |
| lung | 100% | 831.96 | 576 / 578 | 100% | 27.39 | 1154 / 1155 |
| uterus | 100% | 1027.07 | 170 / 170 | 100% | 27.58 | 457 / 459 |
| thymus | 100% | 822.32 | 653 / 653 | 99% | 17.86 | 600 / 605 |
| prostate | 100% | 919.24 | 245 / 245 | 99% | 21.57 | 497 / 502 |
| liver | 100% | 697.22 | 226 / 226 | 98% | 15.06 | 398 / 406 |
| skin | 100% | 1837.09 | 1809 / 1809 | 98% | 22.97 | 462 / 472 |
| kidney | 100% | 772.75 | 89 / 89 | 97% | 16.06 | 876 / 901 |
| brain | 97% | 527.64 | 2563 / 2642 | 100% | 19.72 | 705 / 705 |
| adrenal gland | 100% | 849.59 | 257 / 258 | 93% | 14.31 | 215 / 230 |
| adipose | 100% | 1013.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 26.03 | 29 / 29 |
| muscle | 100% | 1225.50 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 958.81 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 22.21 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.30 | 1 / 1 |
| blood vessel | 100% | 912.90 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 13.55 | 76 / 80 |
| heart | 95% | 557.77 | 816 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 75% | 555.59 | 693 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006890 | Biological process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| GO_0000070 | Biological process | mitotic sister chromatid segregation |
| GO_0051988 | Biological process | regulation of attachment of spindle microtubules to kinetochore |
| GO_0007096 | Biological process | regulation of exit from mitosis |
| GO_0000132 | Biological process | establishment of mitotic spindle orientation |
| GO_0051301 | Biological process | cell division |
| GO_0065003 | Biological process | protein-containing complex assembly |
| GO_0034501 | Biological process | protein localization to kinetochore |
| GO_0051321 | Biological process | meiotic cell cycle |
| GO_0007030 | Biological process | Golgi organization |
| GO_0015031 | Biological process | protein transport |
| GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO_0007094 | Biological process | mitotic spindle assembly checkpoint signaling |
| GO_0007080 | Biological process | mitotic metaphase chromosome alignment |
| GO_0005811 | Cellular component | lipid droplet |
| GO_0070939 | Cellular component | Dsl1/NZR complex |
| GO_0000922 | Cellular component | spindle pole |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_1990423 | Cellular component | RZZ complex |
| GO_0000776 | Cellular component | kinetochore |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005829 | Cellular component | cytosol |
| GO_0005828 | Cellular component | kinetochore microtubule |
| GO_0005634 | Cellular component | nucleus |
| GO_0019237 | Molecular function | centromeric DNA binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ZW10 |
| Protein name | Centromere/kinetochore protein zw10 homolog Zw10 kinetochore protein |
| Synonyms | |
| Description | FUNCTION: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex . Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER . . |
| Accessions | ENST00000538209.1 F5H3C1 O43264 ENST00000200135.8 [O43264-1] ENST00000535142.5 [O43264-2] |
