PROM1 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	15 studies	43% ± 14%	Explore
retinal cone cell	9 studies	74% ± 21%	Explore
retinal rod cell	9 studies	59% ± 26%	Explore
oligodendrocyte precursor cell	7 studies	26% ± 8%	Explore
respiratory goblet cell	5 studies	32% ± 16%	Explore
duct epithelial cell	4 studies	42% ± 11%	Explore
epithelial cell	4 studies	23% ± 5%	Explore
Mueller cell	4 studies	30% ± 17%	Explore

Name	Number of supported studies	Average coverage
eye	7 studies	38% ± 18%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	1292.21	328 / 328	84%	38.92	149 / 178
intestine	95%	2295.56	915 / 966	85%	43.24	448 / 527
stomach	99%	1358.11	357 / 359	77%	37.88	221 / 286
kidney	100%	3508.74	89 / 89	56%	46.64	502 / 901
bladder	86%	703.52	18 / 21	31%	14.66	157 / 504
brain	89%	360.41	2353 / 2642	27%	5.28	193 / 705
esophagus	65%	321.96	933 / 1445	46%	26.92	84 / 183
breast	61%	2073.37	282 / 459	48%	33.02	533 / 1118
heart	82%	314.55	706 / 861	0%	0	0 / 0
lung	46%	417.07	268 / 578	34%	12.78	395 / 1155
prostate	65%	420.71	160 / 245	9%	1.52	46 / 502
thymus	64%	342.95	421 / 653	4%	0.68	23 / 605
blood vessel	67%	441.85	899 / 1335	0%	0	0 / 0
liver	51%	113.19	115 / 226	13%	6.42	51 / 406
skin	48%	180.22	860 / 1809	6%	2.83	26 / 472
uterus	20%	142.78	34 / 170	30%	16.83	139 / 459
ovary	2%	6.38	3 / 180	29%	7.73	126 / 430
spleen	15%	27.87	36 / 241	0%	0	0 / 0
muscle	8%	15.47	62 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	3%	1.39	2 / 80
tonsil	0%	0	0 / 0	2%	0.45	1 / 45
adipose	2%	6.03	21 / 1204	0%	0	0 / 0
adrenal gland	0%	3.17	1 / 258	0%	0.13	1 / 230
peripheral blood	0%	3.01	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0072139	Biological process	glomerular parietal epithelial cell differentiation
GO_2000768	Biological process	positive regulation of nephron tubule epithelial cell differentiation
GO_0072112	Biological process	podocyte differentiation
GO_0045494	Biological process	photoreceptor cell maintenance
GO_0060042	Biological process	retina morphogenesis in camera-type eye
GO_0060219	Biological process	camera-type eye photoreceptor cell differentiation
GO_0010842	Biological process	retina layer formation
GO_0005902	Cellular component	microvillus
GO_0016324	Cellular component	apical plasma membrane
GO_0005615	Cellular component	extracellular space
GO_0005886	Cellular component	plasma membrane
GO_0001750	Cellular component	photoreceptor outer segment
GO_0031528	Cellular component	microvillus membrane
GO_0070062	Cellular component	extracellular exosome
GO_0071914	Cellular component	prominosome
GO_0009986	Cellular component	cell surface
GO_0042622	Cellular component	photoreceptor outer segment membrane
GO_0005929	Cellular component	cilium
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005793	Cellular component	endoplasmic reticulum-Golgi intermediate compartment
GO_0031982	Cellular component	vesicle
GO_0015485	Molecular function	cholesterol binding
GO_0045296	Molecular function	cadherin binding
GO_0042805	Molecular function	actinin binding
GO_0005515	Molecular function	protein binding

Gene name	PROM1
Protein name	Prominin-1 (Antigen AC133) (Prominin-like protein 1) (CD antigen CD133) Prominin 1
Synonyms	PROML1 MSTP061
Description	FUNCTION: May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner . .
Accessions	ENST00000508322.1 ENST00000675613.1 [O43490-5] ENST00000508167.5 [O43490-2] ENST00000505450.5 [O43490-2] ENST00000508940.1 ENST00000511153.5 ENST00000514967.5 O43490 ENST00000510224.5 [O43490-1] ENST00000539194.6 [O43490-6] H0Y9Q5 H0Y9D4 D6RBI0 D6RCC3 ENST00000513946.2 D6RIF3 ENST00000675377.1 [O43490-7] H0Y9M7 ENST00000447510.7 [O43490-1] ENST00000540805.6 [O43490-4] ENST00000503884.5

PROM1 report