UGGT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0018279Biological processprotein N-linked glycosylation via asparagine
GO_0097359Biological processUDP-glucosylation
GO_0036503Biological processERAD pathway
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0032991Cellular componentprotein-containing complex
GO_0005783Cellular componentendoplasmic reticulum
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0003980Molecular functionUDP-glucose:glycoprotein glucosyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0051082Molecular functionunfolded protein binding

IV. Literature review

[source]
Gene nameUGGT2
Protein nameUDP-glucose:glycoprotein glucosyltransferase 2 (UGT2) (hUGT2) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase 2) (UDP-glucose ceramide glucosyltransferase-like 1)
UDP-glucose glycoprotein glucosyltransferase 2
SynonymsUGCGL2
UGT2
DescriptionFUNCTION: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. .

AccessionsE7EMU6
ENST00000376712.4
A6NP03
Q9NYU1
ENST00000376747.8 [Q9NYU1-1]
ENST00000397618.7
ENST00000376714.7 [Q9NYU1-2]