ICMT report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ICMT at tissue level.

III. Associated gene sets

GO_0046498Biological processS-adenosylhomocysteine metabolic process
GO_0036211Biological processprotein modification process
GO_0006481Biological processC-terminal protein methylation
GO_0006612Biological processprotein targeting to membrane
GO_0046499Biological processS-adenosylmethioninamine metabolic process
GO_0005783Cellular componentendoplasmic reticulum
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0003880Molecular functionprotein C-terminal carboxyl O-methyltransferase activity
GO_0004671Molecular functionprotein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameICMT
Protein nameProtein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT)
Isoprenylcysteine carboxyl methyltransferase
SynonymsPCCMT
DescriptionFUNCTION: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. .

AccessionsENST00000343813.10
K7EQW0
Q7Z750
ENST00000474756.1
ENST00000489498.5
O60725