MRAP2 | OmnibusX

Name	Number of supported studies	Average coverage
brain	4 studies	29% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	84%	455.14	207 / 245	87%	8.20	436 / 502
brain	85%	844.93	2241 / 2642	62%	9.17	438 / 705
pancreas	53%	147.80	175 / 328	89%	16.05	158 / 178
stomach	58%	254.34	208 / 359	71%	9.14	203 / 286
intestine	46%	160.65	440 / 966	80%	13.28	422 / 527
adrenal gland	47%	168.79	121 / 258	65%	109.91	150 / 230
ureter	0%	0	0 / 0	100%	6.81	1 / 1
blood vessel	96%	5094.75	1286 / 1335	0%	0	0 / 0
spleen	95%	887.67	230 / 241	0%	0	0 / 0
uterus	20%	64.58	34 / 170	60%	12.11	276 / 459
esophagus	13%	26.88	187 / 1445	63%	10.56	116 / 183
ovary	31%	93.88	55 / 180	44%	4.61	190 / 430
tonsil	0%	0	0 / 0	69%	8.91	31 / 45
bladder	19%	37.62	4 / 21	45%	6.50	228 / 504
skin	27%	58.66	482 / 1809	37%	5.20	175 / 472
lung	16%	46.76	95 / 578	46%	13.04	527 / 1155
kidney	49%	130.78	44 / 89	12%	1.45	104 / 901
breast	24%	52.40	112 / 459	28%	2.49	309 / 1118
liver	1%	1.77	2 / 226	44%	5.15	179 / 406
adipose	19%	45.41	231 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	19%	1.34	15 / 80
thymus	11%	23.96	72 / 653	6%	0.44	39 / 605
heart	10%	19.62	82 / 861	0%	0	0 / 0
muscle	5%	12.17	41 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0097009	Biological process	energy homeostasis
GO_0072659	Biological process	protein localization to plasma membrane
GO_0007631	Biological process	feeding behavior
GO_0106070	Biological process	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0106072	Biological process	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0106071	Biological process	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0006112	Biological process	energy reserve metabolic process
GO_1903077	Biological process	negative regulation of protein localization to plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0005783	Cellular component	endoplasmic reticulum
GO_0070996	Molecular function	type 1 melanocortin receptor binding
GO_0031780	Molecular function	corticotropin hormone receptor binding
GO_0031781	Molecular function	type 3 melanocortin receptor binding
GO_0030545	Molecular function	signaling receptor regulator activity
GO_0031783	Molecular function	type 5 melanocortin receptor binding
GO_0042802	Molecular function	identical protein binding
GO_0031782	Molecular function	type 4 melanocortin receptor binding
GO_0005515	Molecular function	protein binding

Gene name	MRAP2
Protein name	Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2)
Synonyms	C6orf117
Description	FUNCTION: Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP (By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidence is required in vivo. .
Accessions	ENST00000257776.5 Q96G30

MRAP2 report