CREB3L4 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CREB3L4 at tissue level.

III. Associated gene sets

GO_0006986Biological processresponse to unfolded protein
GO_0007283Biological processspermatogenesis
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000139Cellular componentGolgi membrane
GO_0005739Cellular componentmitochondrion
GO_0005654Cellular componentnucleoplasm
GO_0005783Cellular componentendoplasmic reticulum
GO_0000785Cellular componentchromatin
GO_0005794Cellular componentGolgi apparatus
GO_0031965Cellular componentnuclear membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameCREB3L4
Protein namecAMP responsive element binding protein 3 like 4
Cyclic AMP-responsive element-binding protein 3-like protein 4 (cAMP-responsive element-binding protein 3-like protein 4) (Androgen-induced basic leucine zipper protein) (AIbZIP) (Attaching to CRE-like 1) (ATCE1) (Cyclic AMP-responsive element-binding protein 4) (CREB-4) (cAMP-responsive element-binding protein 4) (Transcript induced in spermiogenesis protein 40) (Tisp40) (hJAL) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 4]
SynonymsJAL
CREB4
AIBZIP
DescriptionFUNCTION: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity). .

AccessionsENST00000368603.5 [Q8TEY5-1]
ENST00000271889.8 [Q8TEY5-1]
ENST00000368601.5
ENST00000431292.1
Q5T4K9
Q8TEY5
Q5T4L1
ENST00000449724.5
ENST00000368600.7 [Q8TEY5-2]
ENST00000368607.8 [Q8TEY5-1]
Q5T4L2