Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 24 studies | 44% ± 15% | |
astrocyte | 19 studies | 50% ± 21% | |
oligodendrocyte | 16 studies | 59% ± 18% | |
microglial cell | 15 studies | 52% ± 14% | |
oligodendrocyte precursor cell | 14 studies | 56% ± 19% | |
glutamatergic neuron | 13 studies | 61% ± 25% | |
macrophage | 12 studies | 40% ± 18% | |
smooth muscle cell | 11 studies | 39% ± 12% | |
GABAergic neuron | 11 studies | 61% ± 23% | |
fibroblast | 11 studies | 46% ± 11% | |
pericyte | 9 studies | 41% ± 12% | |
epithelial cell | 9 studies | 38% ± 18% | |
adipocyte | 9 studies | 63% ± 16% | |
endothelial cell of lymphatic vessel | 9 studies | 51% ± 20% | |
mast cell | 8 studies | 36% ± 9% | |
basal cell | 8 studies | 51% ± 26% | |
neuron | 7 studies | 51% ± 24% | |
dendritic cell | 7 studies | 37% ± 12% | |
ciliated cell | 7 studies | 30% ± 12% | |
interneuron | 6 studies | 69% ± 20% | |
B cell | 6 studies | 34% ± 11% | |
T cell | 6 studies | 40% ± 10% | |
myeloid cell | 6 studies | 38% ± 11% | |
type I pneumocyte | 6 studies | 41% ± 13% | |
club cell | 6 studies | 42% ± 20% | |
retinal cone cell | 5 studies | 59% ± 26% | |
retinal ganglion cell | 5 studies | 51% ± 23% | |
cardiac muscle cell | 5 studies | 61% ± 16% | |
mesothelial cell | 5 studies | 43% ± 13% | |
monocyte | 5 studies | 40% ± 13% | |
type II pneumocyte | 5 studies | 53% ± 9% | |
cholangiocyte | 4 studies | 55% ± 23% | |
hepatocyte | 4 studies | 61% ± 31% | |
glial cell | 4 studies | 34% ± 10% | |
granule cell | 4 studies | 57% ± 12% | |
plasma cell | 4 studies | 41% ± 6% | |
CD4-positive, alpha-beta T cell | 4 studies | 31% ± 8% | |
Mueller cell | 4 studies | 43% ± 14% | |
amacrine cell | 4 studies | 63% ± 10% | |
retina horizontal cell | 4 studies | 49% ± 16% | |
retinal rod cell | 4 studies | 64% ± 10% | |
leukocyte | 4 studies | 44% ± 17% | |
natural killer cell | 4 studies | 37% ± 6% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 51% ± 2% | |
GABAergic interneuron | 3 studies | 62% ± 2% | |
progenitor cell | 3 studies | 39% ± 7% | |
CD8-positive, alpha-beta T cell | 3 studies | 31% ± 7% | |
vein endothelial cell | 3 studies | 40% ± 17% | |
GABAergic amacrine cell | 3 studies | 55% ± 16% | |
OFF-bipolar cell | 3 studies | 47% ± 15% | |
ON-bipolar cell | 3 studies | 48% ± 20% | |
glycinergic amacrine cell | 3 studies | 54% ± 12% | |
endothelial cell of vascular tree | 3 studies | 46% ± 12% | |
retinal pigment epithelial cell | 3 studies | 52% ± 25% | |
abnormal cell | 3 studies | 36% ± 24% | |
ependymal cell | 3 studies | 47% ± 22% | |
alveolar macrophage | 3 studies | 52% ± 10% | |
capillary endothelial cell | 3 studies | 34% ± 6% | |
respiratory goblet cell | 3 studies | 56% ± 19% | |
lymphocyte | 3 studies | 46% ± 14% | |
muscle cell | 3 studies | 44% ± 23% | |
goblet cell | 3 studies | 46% ± 35% | |
transit amplifying cell | 3 studies | 49% ± 35% | |
mural cell | 3 studies | 44% ± 6% | |
mucus secreting cell | 3 studies | 52% ± 11% | |
regulatory T cell | 3 studies | 32% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 2797.75 | 459 / 459 | 100% | 28.21 | 1118 / 1118 |
esophagus | 100% | 3172.65 | 1445 / 1445 | 100% | 25.21 | 183 / 183 |
pancreas | 100% | 1972.45 | 328 / 328 | 100% | 19.77 | 178 / 178 |
prostate | 100% | 2468.89 | 245 / 245 | 100% | 25.25 | 502 / 502 |
stomach | 100% | 2071.53 | 359 / 359 | 100% | 22.09 | 286 / 286 |
thymus | 100% | 2672.52 | 653 / 653 | 100% | 34.41 | 605 / 605 |
bladder | 100% | 3099.33 | 21 / 21 | 100% | 25.77 | 503 / 504 |
skin | 100% | 3452.02 | 1809 / 1809 | 100% | 28.94 | 471 / 472 |
kidney | 100% | 2255.73 | 89 / 89 | 100% | 20.17 | 899 / 901 |
ovary | 100% | 2742.21 | 180 / 180 | 100% | 25.41 | 429 / 430 |
lung | 100% | 2165.31 | 576 / 578 | 100% | 23.17 | 1155 / 1155 |
intestine | 100% | 2899.46 | 966 / 966 | 100% | 23.51 | 525 / 527 |
uterus | 100% | 2704.38 | 170 / 170 | 100% | 32.80 | 457 / 459 |
liver | 100% | 1416.14 | 225 / 226 | 100% | 16.75 | 406 / 406 |
brain | 100% | 2332.99 | 2633 / 2642 | 100% | 23.96 | 702 / 705 |
adrenal gland | 100% | 2187.51 | 258 / 258 | 98% | 17.16 | 225 / 230 |
adipose | 100% | 2510.80 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 26.59 | 29 / 29 |
muscle | 100% | 5988.00 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1782.18 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 34.45 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.31 | 1 / 1 |
blood vessel | 100% | 3136.39 | 1334 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 19.04 | 79 / 80 |
heart | 97% | 2871.63 | 839 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 87% | 1607.49 | 807 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0042176 | Biological process | regulation of protein catabolic process |
GO_1902043 | Biological process | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors |
GO_0031334 | Biological process | positive regulation of protein-containing complex assembly |
GO_0045732 | Biological process | positive regulation of protein catabolic process |
GO_0007253 | Biological process | cytoplasmic sequestering of NF-kappaB |
GO_0045740 | Biological process | positive regulation of DNA replication |
GO_0006915 | Biological process | apoptotic process |
GO_0030155 | Biological process | regulation of cell adhesion |
GO_0043065 | Biological process | positive regulation of apoptotic process |
GO_0036503 | Biological process | ERAD pathway |
GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005654 | Cellular component | nucleoplasm |
GO_0031265 | Cellular component | CD95 death-inducing signaling complex |
GO_0034098 | Cellular component | VCP-NPL4-UFD1 AAA ATPase complex |
GO_0005635 | Cellular component | nuclear envelope |
GO_1990917 | Cellular component | ooplasm |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0019887 | Molecular function | protein kinase regulator activity |
GO_0031072 | Molecular function | heat shock protein binding |
GO_0019901 | Molecular function | protein kinase binding |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0005515 | Molecular function | protein binding |
GO_0043130 | Molecular function | ubiquitin binding |
GO_0051059 | Molecular function | NF-kappaB binding |
Gene name | FAF1 |
Protein name | Fas associated factor 1 (cDNA FLJ37524 fis, clone BRCAN2007119, highly similar to FAS-associated factor 1) FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A) |
Synonyms | UBXD12 CGI-03 UBXN3A |
Description | FUNCTION: Ubiquitin-binding protein . Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation . Potentiates but cannot initiate FAS-induced apoptosis (By similarity). . |
Accessions | ENST00000396153.7 [Q9UNN5-1] ENST00000494400.5 Q9UNN5 B3KT28 |