mRNA splicing, via spliceosome

I. Literature review

[source]
NamemRNA splicing, via spliceosome
IDGO_0000398
collection_id

Biological process

Alternative ID

GO:0006374, GO:0006375

Exact synonym

nuclear mRNA splicing, via spliceosome

Description

The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

Related synonym

splicing AT-AC intron, splicing GT-AG intron

Comment

Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.

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