I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 31% ± 11% | |
| erythroblast | 3 studies | 28% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 31% ± 11% | |
| erythroblast | 3 studies | 28% ± 10% |
Insufficient scRNA-seq data for expression of PPIL1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 1117.42 | 180 / 180 | 100% | 82.84 | 430 / 430 |
| brain | 100% | 1387.96 | 2637 / 2642 | 100% | 117.66 | 705 / 705 |
| esophagus | 100% | 979.99 | 1438 / 1445 | 100% | 74.20 | 183 / 183 |
| bladder | 100% | 1150.10 | 21 / 21 | 99% | 84.56 | 501 / 504 |
| stomach | 100% | 804.96 | 358 / 359 | 100% | 76.33 | 285 / 286 |
| prostate | 100% | 1097.98 | 245 / 245 | 99% | 59.92 | 498 / 502 |
| intestine | 99% | 844.67 | 958 / 966 | 100% | 80.99 | 525 / 527 |
| uterus | 99% | 1118.15 | 169 / 170 | 99% | 90.85 | 455 / 459 |
| breast | 99% | 756.48 | 453 / 459 | 100% | 77.75 | 1116 / 1118 |
| thymus | 100% | 1362.20 | 652 / 653 | 99% | 60.92 | 596 / 605 |
| lung | 97% | 829.35 | 561 / 578 | 100% | 86.37 | 1155 / 1155 |
| adrenal gland | 100% | 2817.22 | 258 / 258 | 96% | 60.20 | 221 / 230 |
| pancreas | 97% | 730.50 | 317 / 328 | 99% | 45.77 | 177 / 178 |
| skin | 96% | 984.54 | 1732 / 1809 | 99% | 102.70 | 469 / 472 |
| liver | 96% | 886.67 | 216 / 226 | 98% | 46.69 | 396 / 406 |
| kidney | 100% | 1126.62 | 89 / 89 | 93% | 38.30 | 837 / 901 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 90.37 | 29 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 76.41 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 76.70 | 1 / 1 |
| spleen | 100% | 819.53 | 240 / 241 | 0% | 0 | 0 / 0 |
| adipose | 97% | 789.96 | 1173 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 97% | 789.93 | 1299 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 97% | 716.20 | 777 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 96% | 58.36 | 77 / 80 |
| heart | 96% | 2238.56 | 826 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 39% | 686.50 | 359 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000398 | Biological process | mRNA splicing, via spliceosome |
| GO_0006457 | Biological process | protein folding |
| GO_1990403 | Biological process | embryonic brain development |
| GO_0000413 | Biological process | protein peptidyl-prolyl isomerization |
| GO_0071013 | Cellular component | catalytic step 2 spliceosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0071007 | Cellular component | U2-type catalytic step 2 spliceosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0097718 | Molecular function | disordered domain specific binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003755 | Molecular function | peptidyl-prolyl cis-trans isomerase activity |
| GO_0016018 | Molecular function | cyclosporin A binding |
| Gene name | PPIL1 |
| Protein name | Peptidyl-prolyl cis-trans isomerase-like 1 (PPIase) (EC 5.2.1.8) (Rotamase PPIL1) |
| Synonyms | CGI-124 CYPL1 UNQ2425/PRO4984 |
| Description | FUNCTION: Involved in pre-mRNA splicing as component of the spliceosome . PPIases accelerate the folding of proteins. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides . Catalyzes prolyl peptide bond isomerization in CDC40/PRP17 . Plays an important role in embryonic brain development; this function is independent of its isomerase activity . . |
| Accessions | Q9Y3C6 ENST00000373699.6 |
