EFTUD2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071466Biological processcellular response to xenobiotic stimulus
GO_0000398Biological processmRNA splicing, via spliceosome
GO_0042220Biological processresponse to cocaine
GO_0046540Cellular componentU4/U6 x U5 tri-snRNP complex
GO_0016020Cellular componentmembrane
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0071007Cellular componentU2-type catalytic step 2 spliceosome
GO_0071005Cellular componentU2-type precatalytic spliceosome
GO_0005829Cellular componentcytosol
GO_0015030Cellular componentCajal body
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0071013Cellular componentcatalytic step 2 spliceosome
GO_0005634Cellular componentnucleus
GO_0005525Molecular functionGTP binding
GO_0030623Molecular functionU5 snRNA binding
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameEFTUD2
Protein name116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Elongation factor Tu GTP binding domain containing 2
SynonymsKIAA0031
SNRP116
DescriptionFUNCTION: Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes . Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). .

AccessionsENST00000588374.1
K7EP67
ENST00000592576.5 [Q15029-3]
K7EIV5
K7EJ74
ENST00000589769.1
ENST00000590124.5
ENST00000426333.7 [Q15029-1]
K7EQ26
ENST00000591856.1
ENST00000592701.2
K7ERJ5
K7EIT3
ENST00000593072.5
Q15029
ENST00000402521.7 [Q15029-2]
ENST00000591382.5 [Q15029-1]