Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 6 studies | 26% ± 11% | |
epithelial cell | 6 studies | 26% ± 8% | |
macrophage | 6 studies | 18% ± 2% | |
classical monocyte | 4 studies | 23% ± 7% | |
myeloid cell | 4 studies | 19% ± 4% | |
hematopoietic precursor cell | 3 studies | 22% ± 2% | |
non-classical monocyte | 3 studies | 23% ± 7% | |
microglial cell | 3 studies | 18% ± 2% | |
ciliated cell | 3 studies | 21% ± 3% | |
GABAergic neuron | 3 studies | 31% ± 8% | |
glutamatergic neuron | 3 studies | 41% ± 10% | |
dendritic cell | 3 studies | 35% ± 10% | |
abnormal cell | 3 studies | 25% ± 4% | |
granulocyte monocyte progenitor cell | 3 studies | 21% ± 5% | |
transit amplifying cell | 3 studies | 26% ± 6% | |
astrocyte | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4088.68 | 1445 / 1445 | 100% | 43.48 | 183 / 183 |
lung | 100% | 4351.33 | 578 / 578 | 100% | 43.45 | 1155 / 1155 |
ovary | 100% | 3364.87 | 180 / 180 | 100% | 28.89 | 430 / 430 |
skin | 100% | 5794.90 | 1809 / 1809 | 100% | 58.84 | 472 / 472 |
stomach | 100% | 3194.89 | 359 / 359 | 100% | 40.78 | 286 / 286 |
uterus | 100% | 3804.52 | 170 / 170 | 100% | 45.57 | 458 / 459 |
breast | 100% | 4588.29 | 459 / 459 | 100% | 40.30 | 1115 / 1118 |
thymus | 100% | 4062.12 | 653 / 653 | 100% | 30.66 | 603 / 605 |
intestine | 100% | 4094.39 | 966 / 966 | 100% | 43.80 | 525 / 527 |
bladder | 100% | 4256.43 | 21 / 21 | 100% | 46.51 | 502 / 504 |
prostate | 100% | 3976.36 | 245 / 245 | 99% | 23.46 | 497 / 502 |
kidney | 100% | 3221.20 | 89 / 89 | 99% | 27.59 | 889 / 901 |
brain | 99% | 2551.01 | 2606 / 2642 | 100% | 44.57 | 705 / 705 |
liver | 100% | 2232.76 | 225 / 226 | 99% | 23.34 | 401 / 406 |
pancreas | 99% | 2341.34 | 324 / 328 | 99% | 30.72 | 177 / 178 |
adrenal gland | 100% | 5032.28 | 258 / 258 | 93% | 19.34 | 214 / 230 |
adipose | 100% | 4443.59 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 56.90 | 29 / 29 |
muscle | 100% | 6093.56 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 5708.87 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 46.20 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 23.35 | 1 / 1 |
blood vessel | 100% | 2984.67 | 1333 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 41.80 | 79 / 80 |
peripheral blood | 98% | 4496.87 | 915 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 3168.74 | 841 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0071466 | Biological process | cellular response to xenobiotic stimulus |
GO_0000398 | Biological process | mRNA splicing, via spliceosome |
GO_0042220 | Biological process | response to cocaine |
GO_0046540 | Cellular component | U4/U6 x U5 tri-snRNP complex |
GO_0016020 | Cellular component | membrane |
GO_0016607 | Cellular component | nuclear speck |
GO_0005654 | Cellular component | nucleoplasm |
GO_0071007 | Cellular component | U2-type catalytic step 2 spliceosome |
GO_0071005 | Cellular component | U2-type precatalytic spliceosome |
GO_0005829 | Cellular component | cytosol |
GO_0015030 | Cellular component | Cajal body |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0071013 | Cellular component | catalytic step 2 spliceosome |
GO_0005634 | Cellular component | nucleus |
GO_0005525 | Molecular function | GTP binding |
GO_0030623 | Molecular function | U5 snRNA binding |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | EFTUD2 |
Protein name | 116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa) Elongation factor Tu GTP binding domain containing 2 |
Synonyms | KIAA0031 SNRP116 |
Description | FUNCTION: Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes . Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). . |
Accessions | ENST00000588374.1 K7EP67 ENST00000592576.5 [Q15029-3] K7EIV5 K7EJ74 ENST00000589769.1 ENST00000590124.5 ENST00000426333.7 [Q15029-1] K7EQ26 ENST00000591856.1 ENST00000592701.2 K7ERJ5 K7EIT3 ENST00000593072.5 Q15029 ENST00000402521.7 [Q15029-2] ENST00000591382.5 [Q15029-1] |