SNRPD1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	31 studies	31% ± 15%	Explore
natural killer cell	31 studies	30% ± 14%	Explore
fibroblast	29 studies	30% ± 13%	Explore
CD8-positive, alpha-beta T cell	28 studies	34% ± 19%	Explore
T cell	27 studies	32% ± 15%	Explore
CD4-positive, alpha-beta T cell	27 studies	33% ± 21%	Explore
endothelial cell	26 studies	35% ± 15%	Explore
conventional dendritic cell	26 studies	34% ± 16%	Explore
pericyte	21 studies	31% ± 12%	Explore
regulatory T cell	21 studies	32% ± 12%	Explore
macrophage	20 studies	27% ± 11%	Explore
basal cell	19 studies	38% ± 17%	Explore
epithelial cell	19 studies	40% ± 21%	Explore
smooth muscle cell	19 studies	31% ± 11%	Explore
memory B cell	17 studies	27% ± 10%	Explore
classical monocyte	17 studies	24% ± 10%	Explore
naive B cell	17 studies	24% ± 6%	Explore
connective tissue cell	16 studies	37% ± 16%	Explore
endothelial cell of lymphatic vessel	15 studies	34% ± 12%	Explore
ciliated cell	15 studies	37% ± 20%	Explore
gamma-delta T cell	15 studies	30% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	28% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	25% ± 5%	Explore
non-classical monocyte	13 studies	29% ± 12%	Explore
monocyte	13 studies	28% ± 10%	Explore
plasmacytoid dendritic cell	13 studies	31% ± 11%	Explore
mast cell	12 studies	25% ± 10%	Explore
plasma cell	12 studies	35% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	31% ± 8%	Explore
mature NK T cell	12 studies	26% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	31% ± 13%	Explore
myofibroblast cell	11 studies	36% ± 14%	Explore
dendritic cell	11 studies	40% ± 26%	Explore
endothelial cell of vascular tree	11 studies	33% ± 10%	Explore
plasmablast	10 studies	44% ± 23%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	31% ± 5%	Explore
capillary endothelial cell	10 studies	26% ± 11%	Explore
abnormal cell	10 studies	37% ± 14%	Explore
vein endothelial cell	10 studies	32% ± 13%	Explore
mucosal invariant T cell	10 studies	26% ± 5%	Explore
myeloid cell	10 studies	28% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	32% ± 10%	Explore
progenitor cell	9 studies	54% ± 16%	Explore
secretory cell	8 studies	36% ± 19%	Explore
endothelial cell of artery	8 studies	29% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	43% ± 20%	Explore
goblet cell	7 studies	34% ± 14%	Explore
innate lymphoid cell	7 studies	23% ± 4%	Explore
neuron	7 studies	40% ± 17%	Explore
T follicular helper cell	7 studies	26% ± 3%	Explore
hematopoietic precursor cell	6 studies	54% ± 25%	Explore
club cell	6 studies	35% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	34% ± 11%	Explore
mesothelial cell	6 studies	48% ± 20%	Explore
transit amplifying cell	6 studies	39% ± 18%	Explore
hematopoietic stem cell	6 studies	49% ± 13%	Explore
precursor B cell	6 studies	43% ± 17%	Explore
erythrocyte	6 studies	42% ± 26%	Explore
leukocyte	5 studies	36% ± 14%	Explore
mononuclear phagocyte	5 studies	33% ± 16%	Explore
kidney loop of Henle epithelial cell	5 studies	21% ± 4%	Explore
intestinal crypt stem cell	5 studies	36% ± 15%	Explore
erythroblast	5 studies	65% ± 22%	Explore
pro-B cell	5 studies	46% ± 13%	Explore
type II pneumocyte	5 studies	35% ± 18%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	37% ± 16%	Explore
pancreatic A cell	4 studies	53% ± 18%	Explore
type B pancreatic cell	4 studies	41% ± 17%	Explore
exhausted T cell	4 studies	43% ± 13%	Explore
epithelial cell of proximal tubule	4 studies	25% ± 12%	Explore
enterocyte	4 studies	27% ± 11%	Explore
enteroendocrine cell	4 studies	51% ± 12%	Explore
immature B cell	4 studies	40% ± 20%	Explore
germinal center B cell	4 studies	43% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	40% ± 9%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	33% ± 9%	Explore
GABAergic neuron	4 studies	22% ± 3%	Explore
glutamatergic neuron	4 studies	29% ± 7%	Explore
granulocyte	4 studies	29% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	72% ± 15%	Explore
T-helper 17 cell	4 studies	39% ± 29%	Explore
deuterosomal cell	3 studies	49% ± 3%	Explore
duct epithelial cell	3 studies	17% ± 1%	Explore
ionocyte	3 studies	26% ± 8%	Explore
precursor cell	3 studies	63% ± 16%	Explore
respiratory goblet cell	3 studies	39% ± 25%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	54% ± 24%	Explore
neural crest cell	3 studies	72% ± 14%	Explore
extravillous trophoblast	3 studies	48% ± 18%	Explore
placental villous trophoblast	3 studies	60% ± 18%	Explore
common myeloid progenitor	3 studies	43% ± 20%	Explore
lymphocyte	3 studies	45% ± 13%	Explore
neuroendocrine cell	3 studies	35% ± 7%	Explore
type I pneumocyte	3 studies	35% ± 13%	Explore
amacrine cell	3 studies	39% ± 13%	Explore
retina horizontal cell	3 studies	32% ± 14%	Explore
alveolar macrophage	3 studies	21% ± 3%	Explore
serous secreting cell	3 studies	26% ± 1%	Explore
intraepithelial lymphocyte	3 studies	31% ± 14%	Explore
muscle cell	3 studies	39% ± 7%	Explore
intermediate monocyte	3 studies	39% ± 19%	Explore
CD4-positive helper T cell	3 studies	22% ± 5%	Explore
myoepithelial cell	3 studies	32% ± 9%	Explore
oligodendrocyte precursor cell	3 studies	35% ± 19%	Explore
granulocyte monocyte progenitor cell	3 studies	61% ± 23%	Explore
group 3 innate lymphoid cell	3 studies	32% ± 17%	Explore
keratinocyte	3 studies	31% ± 8%	Explore
interneuron	3 studies	23% ± 8%	Explore
T-helper 1 cell	3 studies	37% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	27% ± 5%	Explore
double negative thymocyte	3 studies	50% ± 22%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	39% ± 11%	Explore
progenitor cell of mammary luminal epithelium	3 studies	27% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	34% ± 16%	Explore
peripheral blood	14 studies	31% ± 10%	Explore
intestine	10 studies	30% ± 17%	Explore
brain	8 studies	22% ± 5%	Explore
kidney	7 studies	29% ± 11%	Explore
liver	7 studies	33% ± 23%	Explore
lymph node	6 studies	31% ± 19%	Explore
pancreas	5 studies	41% ± 19%	Explore
bone marrow	5 studies	32% ± 8%	Explore
eye	5 studies	29% ± 12%	Explore
uterus	5 studies	33% ± 17%	Explore
placenta	4 studies	42% ± 20%	Explore
prostate	4 studies	29% ± 9%	Explore
breast	4 studies	28% ± 5%	Explore
adrenal gland	3 studies	24% ± 7%	Explore
skin	3 studies	21% ± 3%	Explore
thymus	3 studies	56% ± 29%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	1470.68	966 / 966	100%	43.51	527 / 527
ovary	100%	1636.74	180 / 180	100%	36.61	430 / 430
stomach	100%	1147.45	359 / 359	100%	40.58	286 / 286
uterus	100%	1631.78	170 / 170	100%	57.21	459 / 459
esophagus	100%	1589.40	1444 / 1445	100%	47.47	183 / 183
brain	100%	1640.44	2639 / 2642	100%	36.89	705 / 705
bladder	100%	1681.52	21 / 21	100%	46.49	503 / 504
skin	100%	2190.96	1809 / 1809	100%	37.13	471 / 472
breast	100%	1648.73	459 / 459	100%	40.64	1115 / 1118
thymus	100%	1311.60	653 / 653	100%	30.03	603 / 605
lung	99%	1390.99	575 / 578	100%	40.42	1155 / 1155
prostate	100%	1443.19	245 / 245	99%	24.64	499 / 502
kidney	100%	1351.90	89 / 89	97%	18.11	878 / 901
pancreas	97%	701.59	319 / 328	99%	33.02	177 / 178
adrenal gland	100%	1424.47	258 / 258	97%	27.27	222 / 230
liver	100%	832.83	225 / 226	96%	20.78	388 / 406
lymph node	0%	0	0 / 0	100%	91.31	29 / 29
spleen	100%	1724.53	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	47.90	45 / 45
ureter	0%	0	0 / 0	100%	31.84	1 / 1
adipose	100%	1614.28	1203 / 1204	0%	0	0 / 0
blood vessel	100%	1378.20	1332 / 1335	0%	0	0 / 0
muscle	100%	1238.80	801 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	98%	25.22	78 / 80
heart	97%	886.50	831 / 861	0%	0	0 / 0
peripheral blood	48%	1692.92	449 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000387	Biological process	spliceosomal snRNP assembly
GO_0036261	Biological process	7-methylguanosine cap hypermethylation
GO_1903241	Biological process	U2-type prespliceosome assembly
GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0008380	Biological process	RNA splicing
GO_0000245	Biological process	spliceosomal complex assembly
GO_0046540	Cellular component	U4/U6 x U5 tri-snRNP complex
GO_0005686	Cellular component	U2 snRNP
GO_0000243	Cellular component	commitment complex
GO_0005685	Cellular component	U1 snRNP
GO_0005681	Cellular component	spliceosomal complex
GO_0005654	Cellular component	nucleoplasm
GO_0071007	Cellular component	U2-type catalytic step 2 spliceosome
GO_0071005	Cellular component	U2-type precatalytic spliceosome
GO_0034709	Cellular component	methylosome
GO_0034719	Cellular component	SMN-Sm protein complex
GO_0071011	Cellular component	precatalytic spliceosome
GO_0005829	Cellular component	cytosol
GO_0097526	Cellular component	spliceosomal tri-snRNP complex
GO_0005684	Cellular component	U2-type spliceosomal complex
GO_0005682	Cellular component	U5 snRNP
GO_0005687	Cellular component	U4 snRNP
GO_0034715	Cellular component	pICln-Sm protein complex
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0030532	Cellular component	small nuclear ribonucleoprotein complex
GO_0005689	Cellular component	U12-type spliceosomal complex
GO_0005634	Cellular component	nucleus
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SNRPD1
Protein name	Small nuclear ribonucleoprotein D1 polypeptide Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1) Small nuclear ribonucleoprotein Sm D1 (snRNP core protein D1)
Synonyms
Description	FUNCTION: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome . Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs . May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA . . FUNCTION: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. .
Accessions	ENST00000300413.10 ENST00000582475.1 P62314 J3QLR7 ENST00000579618.1 J3QLI9 Q7Z5A3

SNRPD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review