7-methylguanosine cap hypermethylation

I. Literature review

[source]
Name7-methylguanosine cap hypermethylation
IDGO_0036261
collection_id

Biological process

Exact synonym

2,2,7-trimethylguanosine cap formation, TMG cap formation, conversion of m(7)G to m(3)G, m(7)G cap hypermethylation

Description

Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.

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Genes