SNRPD2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	42 studies	58% ± 18%	Explore
natural killer cell	38 studies	59% ± 16%	Explore
fibroblast	37 studies	53% ± 21%	Explore
CD8-positive, alpha-beta T cell	37 studies	62% ± 21%	Explore
T cell	35 studies	58% ± 21%	Explore
macrophage	33 studies	45% ± 16%	Explore
CD4-positive, alpha-beta T cell	33 studies	67% ± 19%	Explore
endothelial cell	32 studies	45% ± 19%	Explore
conventional dendritic cell	28 studies	64% ± 16%	Explore
pericyte	27 studies	52% ± 20%	Explore
regulatory T cell	27 studies	66% ± 16%	Explore
smooth muscle cell	25 studies	53% ± 19%	Explore
classical monocyte	25 studies	48% ± 15%	Explore
plasmacytoid dendritic cell	24 studies	64% ± 16%	Explore
non-classical monocyte	23 studies	49% ± 15%	Explore
epithelial cell	22 studies	63% ± 21%	Explore
dendritic cell	21 studies	55% ± 23%	Explore
mast cell	21 studies	48% ± 17%	Explore
mature NK T cell	21 studies	57% ± 16%	Explore
plasma cell	21 studies	53% ± 20%	Explore
memory B cell	20 studies	66% ± 10%	Explore
naive B cell	20 studies	55% ± 14%	Explore
basal cell	20 studies	65% ± 17%	Explore
monocyte	19 studies	48% ± 16%	Explore
gamma-delta T cell	19 studies	62% ± 16%	Explore
endothelial cell of lymphatic vessel	18 studies	55% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	64% ± 17%	Explore
connective tissue cell	18 studies	63% ± 21%	Explore
mucosal invariant T cell	16 studies	62% ± 18%	Explore
ciliated cell	16 studies	54% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	57% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	59% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	75% ± 10%	Explore
myofibroblast cell	13 studies	62% ± 20%	Explore
myeloid cell	13 studies	55% ± 19%	Explore
plasmablast	12 studies	64% ± 23%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	66% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	66% ± 16%	Explore
secretory cell	12 studies	60% ± 19%	Explore
capillary endothelial cell	12 studies	37% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	60% ± 17%	Explore
innate lymphoid cell	11 studies	53% ± 16%	Explore
endothelial cell of artery	11 studies	44% ± 16%	Explore
goblet cell	11 studies	47% ± 22%	Explore
vein endothelial cell	11 studies	47% ± 17%	Explore
endothelial cell of vascular tree	11 studies	49% ± 12%	Explore
progenitor cell	10 studies	74% ± 21%	Explore
abnormal cell	10 studies	61% ± 21%	Explore
mesothelial cell	10 studies	73% ± 24%	Explore
type II pneumocyte	9 studies	50% ± 27%	Explore
T follicular helper cell	9 studies	65% ± 12%	Explore
type I pneumocyte	8 studies	41% ± 24%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	66% ± 24%	Explore
leukocyte	8 studies	54% ± 11%	Explore
IgG plasma cell	8 studies	28% ± 17%	Explore
club cell	7 studies	59% ± 10%	Explore
epithelial cell of proximal tubule	7 studies	49% ± 20%	Explore
neuron	7 studies	55% ± 24%	Explore
hematopoietic stem cell	7 studies	87% ± 8%	Explore
precursor B cell	7 studies	60% ± 19%	Explore
hematopoietic precursor cell	6 studies	70% ± 26%	Explore
respiratory goblet cell	6 studies	45% ± 21%	Explore
platelet	6 studies	25% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	75% ± 19%	Explore
kidney loop of Henle epithelial cell	6 studies	44% ± 7%	Explore
renal alpha-intercalated cell	6 studies	62% ± 15%	Explore
enterocyte	6 studies	44% ± 14%	Explore
intestinal crypt stem cell	6 studies	58% ± 26%	Explore
transit amplifying cell	6 studies	53% ± 27%	Explore
immature B cell	6 studies	68% ± 14%	Explore
erythrocyte	6 studies	57% ± 21%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	70% ± 17%	Explore
alveolar macrophage	5 studies	40% ± 10%	Explore
CD4-positive helper T cell	5 studies	49% ± 9%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	62% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	59% ± 14%	Explore
exhausted T cell	5 studies	78% ± 8%	Explore
ionocyte	5 studies	42% ± 11%	Explore
mononuclear phagocyte	5 studies	55% ± 16%	Explore
enteroendocrine cell	5 studies	61% ± 26%	Explore
erythroblast	5 studies	69% ± 27%	Explore
IgA plasma cell	5 studies	35% ± 18%	Explore
pro-B cell	5 studies	64% ± 23%	Explore
brush cell	5 studies	34% ± 23%	Explore
T-helper 17 cell	5 studies	71% ± 21%	Explore
group 3 innate lymphoid cell	5 studies	67% ± 13%	Explore
double negative thymocyte	5 studies	75% ± 12%	Explore
intermediate monocyte	5 studies	66% ± 11%	Explore
granulocyte	5 studies	57% ± 15%	Explore
deuterosomal cell	4 studies	50% ± 14%	Explore
duct epithelial cell	4 studies	52% ± 11%	Explore
pancreatic A cell	4 studies	65% ± 17%	Explore
type B pancreatic cell	4 studies	64% ± 17%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	69% ± 24%	Explore
retinal ganglion cell	4 studies	63% ± 29%	Explore
retinal cone cell	4 studies	55% ± 26%	Explore
retinal rod cell	4 studies	35% ± 18%	Explore
amacrine cell	4 studies	40% ± 19%	Explore
adventitial cell	4 studies	45% ± 5%	Explore
mucus secreting cell	4 studies	39% ± 16%	Explore
neutrophil	4 studies	27% ± 6%	Explore
germinal center B cell	4 studies	66% ± 17%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	64% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	75% ± 29%	Explore
T-helper 1 cell	4 studies	77% ± 11%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	71% ± 21%	Explore
precursor cell	3 studies	88% ± 7%	Explore
squamous epithelial cell	3 studies	34% ± 25%	Explore
monocyte-derived dendritic cell	3 studies	54% ± 27%	Explore
neural crest cell	3 studies	83% ± 11%	Explore
ON-bipolar cell	3 studies	39% ± 25%	Explore
thymocyte	3 studies	58% ± 23%	Explore
extravillous trophoblast	3 studies	86% ± 7%	Explore
placental villous trophoblast	3 studies	80% ± 13%	Explore
common myeloid progenitor	3 studies	62% ± 34%	Explore
lymphocyte	3 studies	66% ± 18%	Explore
megakaryocyte	3 studies	35% ± 13%	Explore
neuroendocrine cell	3 studies	61% ± 21%	Explore
astrocyte	3 studies	37% ± 21%	Explore
retina horizontal cell	3 studies	44% ± 19%	Explore
microglial cell	3 studies	38% ± 18%	Explore
serous secreting cell	3 studies	53% ± 3%	Explore
intraepithelial lymphocyte	3 studies	58% ± 13%	Explore
Mueller cell	3 studies	36% ± 10%	Explore
acinar cell	3 studies	37% ± 5%	Explore
muscle cell	3 studies	58% ± 15%	Explore
oligodendrocyte	3 studies	22% ± 6%	Explore
myoepithelial cell	3 studies	74% ± 4%	Explore
inflammatory macrophage	3 studies	31% ± 7%	Explore
luminal cell of prostate epithelium	3 studies	52% ± 13%	Explore
IgM plasma cell	3 studies	48% ± 15%	Explore
glutamatergic neuron	3 studies	32% ± 11%	Explore
pancreatic ductal cell	3 studies	58% ± 11%	Explore
oligodendrocyte precursor cell	3 studies	47% ± 27%	Explore
granulocyte monocyte progenitor cell	3 studies	68% ± 24%	Explore
glial cell	3 studies	55% ± 28%	Explore
hepatocyte	3 studies	51% ± 30%	Explore
keratinocyte	3 studies	60% ± 6%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	75% ± 9%	Explore
double-positive, alpha-beta thymocyte	3 studies	82% ± 4%	Explore
progenitor cell of mammary luminal epithelium	3 studies	75% ± 15%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	61% ± 12%	Explore
lung	18 studies	56% ± 17%	Explore
intestine	14 studies	44% ± 22%	Explore
kidney	9 studies	50% ± 18%	Explore
brain	7 studies	33% ± 11%	Explore
eye	7 studies	38% ± 15%	Explore
bone marrow	7 studies	46% ± 20%	Explore
lymph node	6 studies	65% ± 10%	Explore
liver	6 studies	50% ± 21%	Explore
pancreas	5 studies	55% ± 19%	Explore
uterus	5 studies	59% ± 21%	Explore
placenta	4 studies	65% ± 21%	Explore
prostate	4 studies	53% ± 19%	Explore
breast	4 studies	58% ± 10%	Explore
adrenal gland	3 studies	52% ± 12%	Explore
esophagus	3 studies	62% ± 26%	Explore
skin	3 studies	48% ± 8%	Explore
thymus	3 studies	69% ± 25%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	4936.12	1445 / 1445	100%	205.88	183 / 183
ovary	100%	7469.31	180 / 180	100%	394.41	430 / 430
skin	100%	6931.16	1809 / 1809	100%	346.58	472 / 472
thymus	100%	4549.68	653 / 653	100%	321.60	605 / 605
uterus	100%	5524.95	170 / 170	100%	471.61	459 / 459
brain	100%	3960.50	2637 / 2642	100%	238.77	705 / 705
prostate	100%	5289.77	245 / 245	100%	318.85	501 / 502
intestine	100%	4749.05	966 / 966	100%	349.84	525 / 527
breast	100%	5527.95	459 / 459	99%	309.19	1111 / 1118
liver	100%	2028.81	225 / 226	100%	230.22	405 / 406
stomach	100%	3776.09	359 / 359	99%	297.24	284 / 286
kidney	100%	4475.71	89 / 89	99%	203.77	894 / 901
bladder	100%	5352.14	21 / 21	99%	402.55	500 / 504
adrenal gland	100%	5122.66	258 / 258	99%	234.18	228 / 230
pancreas	99%	2545.07	326 / 328	99%	276.19	177 / 178
lung	100%	4128.10	577 / 578	99%	316.27	1143 / 1155
adipose	100%	4856.89	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	312.22	80 / 80
lymph node	0%	0	0 / 0	100%	676.48	29 / 29
spleen	100%	5024.91	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	380.84	45 / 45
ureter	0%	0	0 / 0	100%	368.04	1 / 1
blood vessel	100%	4832.46	1334 / 1335	0%	0	0 / 0
heart	99%	3745.33	853 / 861	0%	0	0 / 0
muscle	99%	3375.10	795 / 803	0%	0	0 / 0
peripheral blood	83%	3966.51	770 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000387	Biological process	spliceosomal snRNP assembly
GO_0036261	Biological process	7-methylguanosine cap hypermethylation
GO_1903241	Biological process	U2-type prespliceosome assembly
GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0008380	Biological process	RNA splicing
GO_0000245	Biological process	spliceosomal complex assembly
GO_0046540	Cellular component	U4/U6 x U5 tri-snRNP complex
GO_0005686	Cellular component	U2 snRNP
GO_0005685	Cellular component	U1 snRNP
GO_0005681	Cellular component	spliceosomal complex
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0071007	Cellular component	U2-type catalytic step 2 spliceosome
GO_0071005	Cellular component	U2-type precatalytic spliceosome
GO_0034709	Cellular component	methylosome
GO_0034719	Cellular component	SMN-Sm protein complex
GO_0071011	Cellular component	precatalytic spliceosome
GO_0005829	Cellular component	cytosol
GO_0005684	Cellular component	U2-type spliceosomal complex
GO_0005682	Cellular component	U5 snRNP
GO_0005687	Cellular component	U4 snRNP
GO_0034715	Cellular component	pICln-Sm protein complex
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0030532	Cellular component	small nuclear ribonucleoprotein complex
GO_0005689	Cellular component	U12-type spliceosomal complex
GO_0005634	Cellular component	nucleus
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SNRPD2
Protein name	Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)
Synonyms	LOC645339 SNRPD1
Description	FUNCTION: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome . Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs . . FUNCTION: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. . FUNCTION: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. . FUNCTION: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. .
Accessions	P62316 Q4G1D0 ENST00000587367.5 [P62316-2] ENST00000588301.5 [P62316-1] ENST00000342669.8 [P62316-1] ENST00000588599.5 [P62316-2] ENST00000590212.1 ENST00000391932.7 [P62316-2] K7EJB5 ENST00000585392.2 K7ERG4

SNRPD2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review