SNRPF | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	34 studies	31% ± 11%	Explore
B cell	33 studies	33% ± 12%	Explore
CD8-positive, alpha-beta T cell	32 studies	36% ± 16%	Explore
CD4-positive, alpha-beta T cell	30 studies	37% ± 16%	Explore
fibroblast	30 studies	32% ± 14%	Explore
endothelial cell	29 studies	35% ± 15%	Explore
T cell	27 studies	37% ± 15%	Explore
conventional dendritic cell	27 studies	41% ± 15%	Explore
macrophage	22 studies	27% ± 13%	Explore
pericyte	21 studies	32% ± 13%	Explore
regulatory T cell	21 studies	34% ± 10%	Explore
smooth muscle cell	20 studies	33% ± 13%	Explore
memory B cell	19 studies	29% ± 9%	Explore
basal cell	19 studies	40% ± 14%	Explore
classical monocyte	19 studies	28% ± 12%	Explore
epithelial cell	19 studies	46% ± 22%	Explore
plasmacytoid dendritic cell	18 studies	31% ± 11%	Explore
mature NK T cell	17 studies	29% ± 6%	Explore
gamma-delta T cell	17 studies	32% ± 15%	Explore
endothelial cell of lymphatic vessel	16 studies	35% ± 12%	Explore
connective tissue cell	16 studies	38% ± 17%	Explore
dendritic cell	15 studies	40% ± 25%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	26% ± 8%	Explore
ciliated cell	15 studies	35% ± 19%	Explore
monocyte	15 studies	33% ± 13%	Explore
naive B cell	15 studies	27% ± 7%	Explore
non-classical monocyte	15 studies	27% ± 13%	Explore
mast cell	14 studies	24% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	14 studies	32% ± 8%	Explore
plasma cell	12 studies	31% ± 16%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	36% ± 10%	Explore
capillary endothelial cell	12 studies	28% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	34% ± 14%	Explore
vein endothelial cell	11 studies	33% ± 12%	Explore
mucosal invariant T cell	11 studies	30% ± 5%	Explore
endothelial cell of vascular tree	11 studies	35% ± 9%	Explore
plasmablast	10 studies	43% ± 21%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	32% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	31% ± 6%	Explore
myofibroblast cell	10 studies	39% ± 16%	Explore
abnormal cell	10 studies	38% ± 16%	Explore
myeloid cell	10 studies	38% ± 18%	Explore
secretory cell	9 studies	34% ± 14%	Explore
progenitor cell	9 studies	61% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	32% ± 10%	Explore
endothelial cell of artery	8 studies	26% ± 7%	Explore
goblet cell	8 studies	34% ± 17%	Explore
T follicular helper cell	8 studies	32% ± 7%	Explore
club cell	7 studies	32% ± 12%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	42% ± 18%	Explore
leukocyte	7 studies	35% ± 13%	Explore
epithelial cell of proximal tubule	7 studies	30% ± 16%	Explore
mesothelial cell	7 studies	51% ± 22%	Explore
neuron	7 studies	37% ± 17%	Explore
type II pneumocyte	6 studies	46% ± 20%	Explore
hematopoietic precursor cell	6 studies	53% ± 23%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	35% ± 11%	Explore
kidney loop of Henle epithelial cell	6 studies	25% ± 5%	Explore
hematopoietic stem cell	6 studies	45% ± 17%	Explore
precursor B cell	6 studies	42% ± 16%	Explore
innate lymphoid cell	6 studies	28% ± 4%	Explore
erythrocyte	6 studies	40% ± 27%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	38% ± 14%	Explore
type I pneumocyte	5 studies	34% ± 17%	Explore
mononuclear phagocyte	5 studies	36% ± 15%	Explore
enteroendocrine cell	5 studies	44% ± 19%	Explore
intestinal crypt stem cell	5 studies	45% ± 15%	Explore
transit amplifying cell	5 studies	49% ± 23%	Explore
erythroblast	5 studies	56% ± 18%	Explore
pro-B cell	5 studies	44% ± 10%	Explore
exhausted T cell	4 studies	46% ± 12%	Explore
enterocyte	4 studies	33% ± 13%	Explore
immature B cell	4 studies	44% ± 19%	Explore
CD4-positive helper T cell	4 studies	26% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	36% ± 8%	Explore
glutamatergic neuron	4 studies	28% ± 10%	Explore
oligodendrocyte precursor cell	4 studies	33% ± 18%	Explore
granulocyte	4 studies	30% ± 13%	Explore
hepatocyte	4 studies	42% ± 31%	Explore
T-helper 17 cell	4 studies	43% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	26% ± 6%	Explore
deuterosomal cell	3 studies	48% ± 1%	Explore
duct epithelial cell	3 studies	16% ± 1%	Explore
ionocyte	3 studies	28% ± 6%	Explore
precursor cell	3 studies	59% ± 17%	Explore
pancreatic A cell	3 studies	50% ± 9%	Explore
type B pancreatic cell	3 studies	38% ± 14%	Explore
glomerular endothelial cell	3 studies	22% ± 2%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	62% ± 23%	Explore
neural crest cell	3 studies	68% ± 13%	Explore
extravillous trophoblast	3 studies	48% ± 16%	Explore
placental villous trophoblast	3 studies	57% ± 18%	Explore
common myeloid progenitor	3 studies	45% ± 21%	Explore
lymphocyte	3 studies	49% ± 13%	Explore
megakaryocyte	3 studies	23% ± 6%	Explore
neuroendocrine cell	3 studies	43% ± 5%	Explore
amacrine cell	3 studies	32% ± 12%	Explore
astrocyte	3 studies	24% ± 10%	Explore
retinal cone cell	3 studies	45% ± 19%	Explore
serous secreting cell	3 studies	27% ± 0%	Explore
Mueller cell	3 studies	25% ± 9%	Explore
germinal center B cell	3 studies	48% ± 4%	Explore
intermediate monocyte	3 studies	41% ± 19%	Explore
myoepithelial cell	3 studies	36% ± 8%	Explore
GABAergic neuron	3 studies	26% ± 9%	Explore
granulocyte monocyte progenitor cell	3 studies	62% ± 18%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	64% ± 20%	Explore
group 3 innate lymphoid cell	3 studies	40% ± 17%	Explore
keratinocyte	3 studies	41% ± 4%	Explore
interneuron	3 studies	29% ± 13%	Explore
T-helper 1 cell	3 studies	43% ± 11%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	30% ± 5%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	27% ± 6%	Explore
double negative thymocyte	3 studies	51% ± 26%	Explore
progenitor cell of mammary luminal epithelium	3 studies	33% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	32% ± 11%	Explore
lung	16 studies	35% ± 14%	Explore
intestine	12 studies	31% ± 16%	Explore
kidney	8 studies	33% ± 12%	Explore
brain	8 studies	23% ± 5%	Explore
liver	7 studies	35% ± 20%	Explore
bone marrow	5 studies	27% ± 4%	Explore
eye	5 studies	30% ± 11%	Explore
uterus	5 studies	37% ± 17%	Explore
lymph node	5 studies	36% ± 18%	Explore
pancreas	4 studies	37% ± 15%	Explore
placenta	4 studies	39% ± 20%	Explore
prostate	4 studies	29% ± 10%	Explore
breast	4 studies	32% ± 6%	Explore
adrenal gland	3 studies	30% ± 10%	Explore
esophagus	3 studies	46% ± 27%	Explore
thymus	3 studies	58% ± 27%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	1241.30	258 / 258	100%	40.89	230 / 230
esophagus	100%	1450.00	1445 / 1445	100%	67.06	183 / 183
ovary	100%	1339.06	180 / 180	100%	58.06	430 / 430
skin	100%	1708.89	1809 / 1809	100%	40.68	472 / 472
thymus	100%	1194.33	653 / 653	100%	44.35	605 / 605
uterus	100%	1407.00	170 / 170	100%	82.92	459 / 459
brain	100%	1013.89	2639 / 2642	100%	38.45	705 / 705
intestine	100%	1274.37	966 / 966	100%	70.55	526 / 527
bladder	100%	1232.62	21 / 21	100%	74.91	503 / 504
stomach	100%	990.01	358 / 359	100%	65.81	286 / 286
lung	100%	1257.99	577 / 578	100%	54.70	1151 / 1155
prostate	100%	1154.48	245 / 245	99%	41.45	499 / 502
breast	100%	1380.10	459 / 459	99%	55.06	1106 / 1118
kidney	100%	1282.64	89 / 89	99%	28.76	891 / 901
liver	100%	1085.29	225 / 226	99%	35.71	403 / 406
pancreas	98%	620.61	323 / 328	99%	40.32	176 / 178
adipose	100%	1279.33	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	35.52	80 / 80
lymph node	0%	0	0 / 0	100%	91.61	29 / 29
spleen	100%	1433.22	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	68.30	45 / 45
ureter	0%	0	0 / 0	100%	133.12	1 / 1
blood vessel	100%	1120.80	1331 / 1335	0%	0	0 / 0
muscle	99%	706.06	793 / 803	0%	0	0 / 0
heart	98%	894.98	846 / 861	0%	0	0 / 0
peripheral blood	85%	1337.04	792 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000387	Biological process	spliceosomal snRNP assembly
GO_0036261	Biological process	7-methylguanosine cap hypermethylation
GO_1903241	Biological process	U2-type prespliceosome assembly
GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0008380	Biological process	RNA splicing
GO_0046540	Cellular component	U4/U6 x U5 tri-snRNP complex
GO_0005686	Cellular component	U2 snRNP
GO_0005685	Cellular component	U1 snRNP
GO_0005681	Cellular component	spliceosomal complex
GO_0005654	Cellular component	nucleoplasm
GO_0071007	Cellular component	U2-type catalytic step 2 spliceosome
GO_0071005	Cellular component	U2-type precatalytic spliceosome
GO_0005683	Cellular component	U7 snRNP
GO_0034709	Cellular component	methylosome
GO_0034719	Cellular component	SMN-Sm protein complex
GO_0005829	Cellular component	cytosol
GO_0005684	Cellular component	U2-type spliceosomal complex
GO_0005682	Cellular component	U5 snRNP
GO_0005687	Cellular component	U4 snRNP
GO_0034715	Cellular component	pICln-Sm protein complex
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0030532	Cellular component	small nuclear ribonucleoprotein complex
GO_0005689	Cellular component	U12-type spliceosomal complex
GO_0005634	Cellular component	nucleus
GO_0003723	Molecular function	RNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SNRPF
Protein name	Sm protein F Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF) Small nuclear ribonucleoprotein polypeptide F
Synonyms	PBSCF
Description	FUNCTION: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome . Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs . As part of the U7 snRNP it is involved in histone 3'-end processing . .
Accessions	P62306 ENST00000553192.5 F8W0W6 ENST00000552085.1 ENST00000266735.10 A0A0B4J254

SNRPF report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review