TRA2A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	40 studies	32% ± 13%	Explore
B cell	35 studies	31% ± 14%	Explore
natural killer cell	34 studies	26% ± 9%	Explore
fibroblast	34 studies	27% ± 11%	Explore
T cell	25 studies	25% ± 8%	Explore
smooth muscle cell	25 studies	25% ± 8%	Explore
pericyte	25 studies	27% ± 11%	Explore
CD4-positive, alpha-beta T cell	24 studies	25% ± 9%	Explore
macrophage	24 studies	28% ± 13%	Explore
CD8-positive, alpha-beta T cell	22 studies	24% ± 7%	Explore
mast cell	20 studies	23% ± 8%	Explore
memory B cell	20 studies	27% ± 7%	Explore
astrocyte	19 studies	40% ± 17%	Explore
naive B cell	18 studies	27% ± 8%	Explore
regulatory T cell	18 studies	25% ± 5%	Explore
monocyte	16 studies	26% ± 8%	Explore
endothelial cell of lymphatic vessel	16 studies	27% ± 10%	Explore
oligodendrocyte precursor cell	16 studies	45% ± 21%	Explore
mature NK T cell	16 studies	24% ± 8%	Explore
gamma-delta T cell	15 studies	27% ± 11%	Explore
microglial cell	15 studies	36% ± 13%	Explore
classical monocyte	14 studies	25% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	30% ± 9%	Explore
oligodendrocyte	14 studies	50% ± 18%	Explore
plasmacytoid dendritic cell	14 studies	25% ± 9%	Explore
epithelial cell	14 studies	39% ± 22%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	23% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	27% ± 10%	Explore
basal cell	13 studies	32% ± 18%	Explore
ciliated cell	13 studies	35% ± 17%	Explore
non-classical monocyte	12 studies	25% ± 13%	Explore
connective tissue cell	12 studies	27% ± 8%	Explore
GABAergic neuron	11 studies	44% ± 21%	Explore
conventional dendritic cell	11 studies	29% ± 16%	Explore
mucosal invariant T cell	11 studies	22% ± 4%	Explore
type I pneumocyte	10 studies	37% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	25% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	28% ± 11%	Explore
capillary endothelial cell	10 studies	19% ± 4%	Explore
myofibroblast cell	10 studies	28% ± 10%	Explore
glutamatergic neuron	10 studies	51% ± 23%	Explore
endothelial cell of vascular tree	10 studies	24% ± 11%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	21% ± 6%	Explore
endothelial cell of artery	9 studies	20% ± 2%	Explore
myeloid cell	9 studies	27% ± 10%	Explore
adipocyte	9 studies	35% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	28% ± 7%	Explore
abnormal cell	8 studies	27% ± 13%	Explore
neuron	8 studies	44% ± 21%	Explore
vein endothelial cell	8 studies	24% ± 14%	Explore
club cell	8 studies	32% ± 13%	Explore
type II pneumocyte	8 studies	34% ± 7%	Explore
dendritic cell	8 studies	34% ± 16%	Explore
leukocyte	7 studies	32% ± 10%	Explore
progenitor cell	7 studies	28% ± 7%	Explore
T follicular helper cell	7 studies	24% ± 6%	Explore
interneuron	6 studies	55% ± 19%	Explore
precursor B cell	6 studies	38% ± 11%	Explore
innate lymphoid cell	6 studies	26% ± 8%	Explore
amacrine cell	6 studies	33% ± 6%	Explore
retinal cone cell	6 studies	33% ± 10%	Explore
retinal rod cell	6 studies	37% ± 7%	Explore
mesothelial cell	6 studies	42% ± 12%	Explore
Mueller cell	6 studies	33% ± 11%	Explore
plasma cell	5 studies	29% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	20% ± 1%	Explore
mononuclear phagocyte	5 studies	25% ± 11%	Explore
pro-B cell	5 studies	33% ± 6%	Explore
retina horizontal cell	5 studies	28% ± 7%	Explore
cardiac muscle cell	5 studies	24% ± 3%	Explore
lymphocyte	5 studies	37% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	26% ± 10%	Explore
goblet cell	5 studies	38% ± 23%	Explore
hematopoietic precursor cell	4 studies	40% ± 18%	Explore
glial cell	4 studies	34% ± 15%	Explore
granule cell	4 studies	34% ± 6%	Explore
immature B cell	4 studies	43% ± 8%	Explore
retinal bipolar neuron	4 studies	35% ± 8%	Explore
retinal pigment epithelial cell	4 studies	37% ± 22%	Explore
secretory cell	4 studies	26% ± 12%	Explore
hepatocyte	4 studies	46% ± 15%	Explore
enteroendocrine cell	4 studies	27% ± 11%	Explore
respiratory goblet cell	4 studies	41% ± 13%	Explore
alveolar macrophage	4 studies	29% ± 10%	Explore
transit amplifying cell	4 studies	35% ± 26%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	21% ± 4%	Explore
kidney loop of Henle epithelial cell	4 studies	20% ± 6%	Explore
squamous epithelial cell	3 studies	42% ± 25%	Explore
effector CD4-positive, alpha-beta T cell	3 studies	25% ± 8%	Explore
exhausted T cell	3 studies	33% ± 15%	Explore
plasmablast	3 studies	53% ± 19%	Explore
podocyte	3 studies	30% ± 6%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	31% ± 5%	Explore
renal alpha-intercalated cell	3 studies	29% ± 10%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	36% ± 15%	Explore
neural crest cell	3 studies	22% ± 4%	Explore
GABAergic interneuron	3 studies	35% ± 4%	Explore
retinal ganglion cell	3 studies	27% ± 8%	Explore
tissue-resident macrophage	3 studies	23% ± 2%	Explore
GABAergic amacrine cell	3 studies	35% ± 2%	Explore
OFF-bipolar cell	3 studies	29% ± 8%	Explore
ON-bipolar cell	3 studies	36% ± 11%	Explore
glycinergic amacrine cell	3 studies	33% ± 1%	Explore
rod bipolar cell	3 studies	35% ± 9%	Explore
germinal center B cell	3 studies	28% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	22% ± 9%	Explore
muscle cell	3 studies	35% ± 19%	Explore
ependymal cell	3 studies	49% ± 17%	Explore
hematopoietic stem cell	3 studies	23% ± 7%	Explore
intestinal crypt stem cell	3 studies	22% ± 4%	Explore
adventitial cell	3 studies	27% ± 7%	Explore
chondrocyte	3 studies	34% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	40% ± 10%	Explore
Schwann cell	3 studies	39% ± 14%	Explore
brush cell	3 studies	25% ± 5%	Explore
keratinocyte	3 studies	27% ± 7%	Explore
T-helper 17 cell	3 studies	25% ± 7%	Explore
double negative thymocyte	3 studies	33% ± 17%	Explore
myoepithelial cell	3 studies	28% ± 12%	Explore
mural cell	3 studies	40% ± 12%	Explore
mucus secreting cell	3 studies	31% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	18 studies	45% ± 20%	Explore
lung	16 studies	28% ± 9%	Explore
peripheral blood	13 studies	29% ± 15%	Explore
intestine	9 studies	23% ± 11%	Explore
eye	9 studies	35% ± 12%	Explore
kidney	6 studies	24% ± 6%	Explore
heart	5 studies	24% ± 3%	Explore
liver	5 studies	34% ± 16%	Explore
bone marrow	4 studies	22% ± 6%	Explore
uterus	4 studies	31% ± 12%	Explore
breast	4 studies	20% ± 3%	Explore
adipose	4 studies	37% ± 11%	Explore
skin	3 studies	22% ± 3%	Explore
lymph node	3 studies	28% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	4810.19	21 / 21	100%	73.06	504 / 504
esophagus	100%	4612.77	1445 / 1445	100%	48.37	183 / 183
ovary	100%	6966.41	180 / 180	100%	49.62	430 / 430
prostate	100%	5657.83	245 / 245	100%	71.76	502 / 502
stomach	100%	3410.51	359 / 359	100%	51.92	286 / 286
uterus	100%	6419.88	170 / 170	100%	77.68	459 / 459
breast	100%	4495.04	459 / 459	100%	80.33	1117 / 1118
thymus	100%	5453.93	653 / 653	100%	74.88	604 / 605
lung	100%	4570.55	577 / 578	100%	67.13	1155 / 1155
brain	100%	3979.50	2637 / 2642	100%	67.99	705 / 705
intestine	100%	4790.61	966 / 966	100%	57.81	526 / 527
adrenal gland	100%	4374.14	258 / 258	100%	60.69	229 / 230
pancreas	100%	2638.48	328 / 328	99%	58.34	176 / 178
kidney	100%	3567.45	89 / 89	99%	49.39	889 / 901
liver	100%	2300.90	226 / 226	98%	30.23	398 / 406
skin	100%	4507.29	1809 / 1809	90%	49.29	426 / 472
adipose	100%	4171.57	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	80.09	29 / 29
spleen	100%	6817.73	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	58.29	45 / 45
ureter	0%	0	0 / 0	100%	32.76	1 / 1
blood vessel	100%	3391.02	1334 / 1335	0%	0	0 / 0
heart	100%	2291.75	857 / 861	0%	0	0 / 0
muscle	95%	1387.31	760 / 803	0%	0	0 / 0
peripheral blood	89%	2772.98	827 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	81%	27.52	65 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	TRA2A
Protein name	Transformer 2 alpha homolog Putative MAPK activating protein (Transformer-2 alpha, isoform CRA_a) (cDNA, FLJ95674, Homo sapiens transformer-2 alpha (htra-2 alpha) (HSU53209), mRNA) Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Synonyms	hCG_37979 HSU53209
Description	FUNCTION: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. .
Accessions	ENST00000621813.4 [Q13595-3] ENST00000448549.1 F8WEH2 ENST00000297071.9 [Q13595-1] Q13595 Q549U1 ENST00000392502.8 [Q13595-4] A0A8J9ASM4 ENST00000538367.6

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0048026	Biological process	positive regulation of mRNA splicing, via spliceosome
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0005681	Cellular component	spliceosomal complex
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

TRA2A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review