DHX8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006396Biological processRNA processing
GO_0000398Biological processmRNA splicing, via spliceosome
GO_0008380Biological processRNA splicing
GO_0000390Biological processspliceosomal complex disassembly
GO_0005622Cellular componentintracellular anatomical structure
GO_0005681Cellular componentspliceosomal complex
GO_0005654Cellular componentnucleoplasm
GO_0071007Cellular componentU2-type catalytic step 2 spliceosome
GO_0016604Cellular componentnuclear body
GO_0005829Cellular componentcytosol
GO_0071013Cellular componentcatalytic step 2 spliceosome
GO_0005634Cellular componentnucleus
GO_0003724Molecular functionRNA helicase activity
GO_0042802Molecular functionidentical protein binding
GO_0008186Molecular functionATP-dependent activity, acting on RNA
GO_0005524Molecular functionATP binding
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameDHX8
Protein nameRNA helicase (EC 3.6.4.13)
DEAH-box helicase 8
DHX8 protein
ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1)
SynonymshCG_28537
DDX8
DescriptionFUNCTION: Involved in pre-mRNA splicing as component of the spliceosome . Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome . .

AccessionsQ86X36
K7EQH7
Q86YB2
F5H658
ENST00000262415.8
Q05CV4
Q14562
ENST00000540306.5
ENST00000650571.1
K7END7
ENST00000589898.2
K7EJH9
ENST00000592258.5
ENST00000587574.1