TXNL4A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	18 studies	24% ± 9%	Explore
B cell	14 studies	24% ± 7%	Explore
natural killer cell	12 studies	24% ± 8%	Explore
ciliated cell	12 studies	31% ± 16%	Explore
classical monocyte	12 studies	24% ± 15%	Explore
CD8-positive, alpha-beta T cell	12 studies	24% ± 10%	Explore
fibroblast	12 studies	21% ± 8%	Explore
epithelial cell	12 studies	33% ± 20%	Explore
smooth muscle cell	12 studies	20% ± 4%	Explore
plasmacytoid dendritic cell	12 studies	29% ± 7%	Explore
basal cell	11 studies	27% ± 15%	Explore
macrophage	10 studies	23% ± 7%	Explore
CD4-positive, alpha-beta T cell	10 studies	24% ± 9%	Explore
pericyte	10 studies	20% ± 5%	Explore
plasma cell	9 studies	31% ± 13%	Explore
conventional dendritic cell	9 studies	28% ± 18%	Explore
T cell	8 studies	18% ± 2%	Explore
mast cell	8 studies	22% ± 6%	Explore
endothelial cell of lymphatic vessel	8 studies	24% ± 6%	Explore
plasmablast	7 studies	41% ± 21%	Explore
non-classical monocyte	7 studies	33% ± 19%	Explore
monocyte	6 studies	20% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	22% ± 4%	Explore
dendritic cell	6 studies	47% ± 29%	Explore
neuron	6 studies	38% ± 12%	Explore
gamma-delta T cell	6 studies	28% ± 17%	Explore
abnormal cell	6 studies	30% ± 11%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	27% ± 8%	Explore
respiratory goblet cell	5 studies	25% ± 15%	Explore
secretory cell	5 studies	26% ± 20%	Explore
naive B cell	5 studies	20% ± 4%	Explore
hematopoietic precursor cell	5 studies	30% ± 13%	Explore
connective tissue cell	5 studies	24% ± 8%	Explore
myeloid cell	5 studies	31% ± 13%	Explore
regulatory T cell	5 studies	21% ± 3%	Explore
GABAergic neuron	5 studies	30% ± 13%	Explore
pancreatic A cell	4 studies	46% ± 7%	Explore
type B pancreatic cell	4 studies	41% ± 10%	Explore
endothelial cell of artery	4 studies	19% ± 2%	Explore
capillary endothelial cell	4 studies	18% ± 2%	Explore
pro-B cell	4 studies	23% ± 3%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	25% ± 14%	Explore
innate lymphoid cell	4 studies	17% ± 3%	Explore
glutamatergic neuron	4 studies	44% ± 17%	Explore
oligodendrocyte precursor cell	4 studies	29% ± 4%	Explore
enteroendocrine cell	4 studies	28% ± 11%	Explore
goblet cell	4 studies	27% ± 9%	Explore
astrocyte	4 studies	22% ± 4%	Explore
oligodendrocyte	4 studies	29% ± 9%	Explore
club cell	3 studies	27% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	25% ± 5%	Explore
leukocyte	3 studies	30% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	26% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	33% ± 10%	Explore
mononuclear phagocyte	3 studies	27% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	25% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	36% ± 12%	Explore
mature NK T cell	3 studies	27% ± 4%	Explore
neural crest cell	3 studies	24% ± 8%	Explore
transit amplifying cell	3 studies	22% ± 2%	Explore
retinal ganglion cell	3 studies	52% ± 22%	Explore
lymphocyte	3 studies	25% ± 10%	Explore
myofibroblast cell	3 studies	18% ± 2%	Explore
brush cell	3 studies	36% ± 13%	Explore
precursor B cell	3 studies	20% ± 1%	Explore
type II pneumocyte	3 studies	29% ± 12%	Explore
retina horizontal cell	3 studies	27% ± 9%	Explore
retinal cone cell	3 studies	37% ± 13%	Explore
serous secreting cell	3 studies	18% ± 0%	Explore
germinal center B cell	3 studies	23% ± 7%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	26% ± 1%	Explore
memory B cell	3 studies	18% ± 1%	Explore
granulocyte monocyte progenitor cell	3 studies	35% ± 12%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	31% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	26% ± 10%	Explore
interneuron	3 studies	34% ± 20%	Explore
microglial cell	3 studies	20% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	11 studies	27% ± 13%	Explore
brain	7 studies	31% ± 11%	Explore
peripheral blood	6 studies	33% ± 14%	Explore
intestine	5 studies	22% ± 7%	Explore
pancreas	4 studies	38% ± 12%	Explore
liver	4 studies	28% ± 13%	Explore
placenta	3 studies	19% ± 3%	Explore
eye	3 studies	22% ± 6%	Explore
breast	3 studies	19% ± 3%	Explore
bone marrow	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	3331.57	2642 / 2642	100%	39.98	705 / 705
esophagus	100%	2305.91	1445 / 1445	100%	24.62	183 / 183
liver	100%	1881.05	226 / 226	100%	26.58	406 / 406
ovary	100%	1285.93	180 / 180	100%	34.80	430 / 430
pancreas	100%	1986.71	328 / 328	100%	23.02	178 / 178
prostate	100%	2139.14	245 / 245	100%	36.69	502 / 502
skin	100%	2871.08	1809 / 1809	100%	45.11	472 / 472
stomach	100%	1960.12	359 / 359	100%	28.64	286 / 286
uterus	100%	1543.33	170 / 170	100%	39.05	459 / 459
breast	100%	2198.30	459 / 459	100%	40.00	1117 / 1118
thymus	100%	2187.19	653 / 653	100%	33.46	604 / 605
intestine	100%	2250.02	966 / 966	100%	30.39	526 / 527
bladder	100%	1984.90	21 / 21	100%	31.84	503 / 504
kidney	100%	2676.69	89 / 89	100%	24.74	899 / 901
adrenal gland	100%	2797.46	258 / 258	100%	35.68	229 / 230
lung	99%	2099.45	575 / 578	100%	28.36	1154 / 1155
adipose	100%	2296.01	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	42.26	80 / 80
lymph node	0%	0	0 / 0	100%	63.21	29 / 29
muscle	100%	2463.68	803 / 803	0%	0	0 / 0
spleen	100%	2433.49	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	36.71	45 / 45
ureter	0%	0	0 / 0	100%	32.64	1 / 1
blood vessel	100%	2045.51	1330 / 1335	0%	0	0 / 0
heart	99%	1878.42	849 / 861	0%	0	0 / 0
peripheral blood	96%	1754.10	892 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0000245	Biological process	spliceosomal complex assembly
GO_0051301	Biological process	cell division
GO_0000375	Biological process	RNA splicing, via transesterification reactions
GO_0046540	Cellular component	U4/U6 x U5 tri-snRNP complex
GO_0005682	Cellular component	U5 snRNP
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005681	Cellular component	spliceosomal complex
GO_0071005	Cellular component	U2-type precatalytic spliceosome
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	TXNL4A
Protein name	Thioredoxin like 4A Thioredoxin-like protein 4A (DIM1 protein homolog) (Spliceosomal U5 snRNP-specific 15 kDa protein) (Thioredoxin-like U5 snRNP protein U5-15kD) Dim1p homolog (Thioredoxin like 4A) (Thioredoxin-like 4A, isoform CRA_a)
Synonyms	DIM1 hCG_16170 TXNL4
Description	FUNCTION: Plays a role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). .
Accessions	ENST00000588162.1 ENST00000355491.5 ENST00000591711.5 ENST00000586825.1 P83876 ENST00000269601.10 ENST00000585474.5 ENST00000586295.1 K7ESL1 K7EPA6 K7ES07 ENST00000592957.1 ENST00000592837.1 K7EJU2 ENST00000585769.5 O14835 K7EMX5

TXNL4A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review