RNA splicing, via transesterification reactions

I. Literature review

[source]
NameRNA splicing, via transesterification reactions
IDGO_0000375
collection_id

Biological process

Alternative ID

GO:0000385, GO:0031202

Description

Splicing of RNA via a series of two transesterification reactions.

Related synonym

RNA splicing factor activity, transesterification mechanism, pre-mRNA splicing factor activity, spliceosomal catalysis

Comment

Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism.

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