SNRNP40 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	12 studies	21% ± 7%	Explore
CD8-positive, alpha-beta T cell	11 studies	23% ± 5%	Explore
endothelial cell	8 studies	25% ± 9%	Explore
regulatory T cell	8 studies	20% ± 4%	Explore
T cell	6 studies	20% ± 4%	Explore
CD4-positive, alpha-beta T cell	6 studies	27% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	18% ± 2%	Explore
B cell	6 studies	20% ± 7%	Explore
oligodendrocyte	6 studies	21% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	19% ± 3%	Explore
epithelial cell	5 studies	34% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	20% ± 4%	Explore
fibroblast	5 studies	24% ± 8%	Explore
plasmacytoid dendritic cell	5 studies	22% ± 6%	Explore
hematopoietic precursor cell	4 studies	25% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	20% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
precursor B cell	4 studies	25% ± 8%	Explore
ciliated cell	4 studies	22% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	27% ± 8%	Explore
glutamatergic neuron	4 studies	35% ± 14%	Explore
oligodendrocyte precursor cell	4 studies	20% ± 3%	Explore
astrocyte	4 studies	19% ± 4%	Explore
gamma-delta T cell	4 studies	28% ± 17%	Explore
plasmablast	3 studies	43% ± 12%	Explore
conventional dendritic cell	3 studies	32% ± 11%	Explore
connective tissue cell	3 studies	23% ± 5%	Explore
neural crest cell	3 studies	20% ± 4%	Explore
erythroblast	3 studies	35% ± 17%	Explore
pericyte	3 studies	21% ± 4%	Explore
pro-B cell	3 studies	23% ± 4%	Explore
exhausted T cell	3 studies	20% ± 2%	Explore
macrophage	3 studies	19% ± 2%	Explore
GABAergic neuron	3 studies	35% ± 7%	Explore
dendritic cell	3 studies	37% ± 7%	Explore
basal cell	3 studies	30% ± 8%	Explore
transit amplifying cell	3 studies	27% ± 8%	Explore
neuron	3 studies	28% ± 8%	Explore
naive B cell	3 studies	20% ± 3%	Explore
double negative thymocyte	3 studies	27% ± 14%	Explore
memory B cell	3 studies	21% ± 5%	Explore
mucosal invariant T cell	3 studies	18% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	4 studies	18% ± 3%	Explore
lung	4 studies	22% ± 5%	Explore
brain	4 studies	33% ± 7%	Explore
liver	3 studies	31% ± 18%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1347.42	1445 / 1445	100%	26.42	183 / 183
lung	100%	1372.68	578 / 578	100%	38.05	1155 / 1155
ovary	100%	1543.62	180 / 180	100%	34.85	430 / 430
stomach	100%	1076.55	359 / 359	100%	30.47	286 / 286
breast	100%	1695.03	459 / 459	100%	42.91	1117 / 1118
intestine	100%	1443.52	966 / 966	100%	35.22	526 / 527
uterus	100%	1780.48	170 / 170	100%	49.79	458 / 459
prostate	100%	1543.25	245 / 245	100%	38.18	500 / 502
thymus	100%	1475.53	653 / 653	100%	31.15	602 / 605
bladder	100%	1529.52	21 / 21	99%	39.39	501 / 504
skin	100%	1882.66	1809 / 1809	99%	38.58	469 / 472
brain	99%	1027.70	2625 / 2642	100%	30.37	705 / 705
pancreas	99%	661.45	325 / 328	99%	25.15	177 / 178
kidney	100%	1107.85	89 / 89	96%	17.64	862 / 901
liver	100%	670.83	226 / 226	94%	14.46	380 / 406
adrenal gland	100%	1495.24	258 / 258	93%	20.34	215 / 230
adipose	100%	1524.77	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	51.70	29 / 29
spleen	100%	1950.19	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	50.13	45 / 45
ureter	0%	0	0 / 0	100%	12.14	1 / 1
blood vessel	100%	1205.06	1334 / 1335	0%	0	0 / 0
muscle	100%	986.46	802 / 803	0%	0	0 / 0
heart	99%	834.41	850 / 861	0%	0	0 / 0
peripheral blood	97%	1493.80	897 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	95%	17.68	76 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0008380	Biological process	RNA splicing
GO_0000375	Biological process	RNA splicing, via transesterification reactions
GO_0006396	Biological process	RNA processing
GO_0005732	Cellular component	sno(s)RNA-containing ribonucleoprotein complex
GO_0016607	Cellular component	nuclear speck
GO_0046540	Cellular component	U4/U6 x U5 tri-snRNP complex
GO_0005682	Cellular component	U5 snRNP
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0071007	Cellular component	U2-type catalytic step 2 spliceosome
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	SNRNP40
Protein name	Small nuclear ribonucleoprotein U5 subunit 40 (WD repeat domain 57 (U5 snRNP specific), isoform CRA_b) U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Synonyms	PRP8BP DKFZp434D199 hCG_20041 SFP38 WDR57
Description	FUNCTION: Required for pre-mRNA splicing as component of the activated spliceosome . Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). .
Accessions	ENST00000373720.3 ENST00000263694.9 [Q96DI7-1] Q96DI7 Q9NSS8

SNRNP40 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review