PRPF4 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of PRPF4 at tissue level.

III. Associated gene sets

GO_0000398Biological processmRNA splicing, via spliceosome
GO_0008380Biological processRNA splicing
GO_0000375Biological processRNA splicing, via transesterification reactions
GO_0006396Biological processRNA processing
GO_0015030Cellular componentCajal body
GO_0097525Cellular componentspliceosomal snRNP complex
GO_0016607Cellular componentnuclear speck
GO_0046540Cellular componentU4/U6 x U5 tri-snRNP complex
GO_0005654Cellular componentnucleoplasm
GO_0071001Cellular componentU4/U6 snRNP
GO_0005681Cellular componentspliceosomal complex
GO_0071005Cellular componentU2-type precatalytic spliceosome
GO_0005634Cellular componentnucleus
GO_0017070Molecular functionU6 snRNA binding
GO_0030621Molecular functionU4 snRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePRPF4
Protein nameU4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)
60 kDa U4/U6 snRNP-specific spliceosomal protein (PRP4 pre-mRNA processing factor 4 homolog (Yeast), isoform CRA_b)
PRPF4 protein
SynonymshCG_29193
PRP4
DescriptionFUNCTION: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). .

AccessionsQ5T1M7
ENST00000374198.5 [O43172-2]
O43172
ENST00000374199.9 [O43172-1]
Q6IAP9