Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 28% ± 7% | |
| dendritic cell | 3 studies | 24% ± 1% |
Insufficient scRNA-seq data for expression of PRPF4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 1718.10 | 459 / 459 | 100% | 42.43 | 1118 / 1118 |
| esophagus | 100% | 1611.15 | 1445 / 1445 | 100% | 42.04 | 183 / 183 |
| lung | 100% | 1463.53 | 578 / 578 | 100% | 37.89 | 1155 / 1155 |
| ovary | 100% | 2087.49 | 180 / 180 | 100% | 31.61 | 430 / 430 |
| prostate | 100% | 2088.78 | 245 / 245 | 100% | 31.88 | 502 / 502 |
| stomach | 100% | 1215.35 | 359 / 359 | 100% | 34.28 | 286 / 286 |
| uterus | 100% | 1698.81 | 170 / 170 | 100% | 44.60 | 459 / 459 |
| intestine | 100% | 1547.47 | 966 / 966 | 100% | 38.28 | 526 / 527 |
| skin | 100% | 2547.24 | 1809 / 1809 | 100% | 36.26 | 471 / 472 |
| bladder | 100% | 1716.19 | 21 / 21 | 100% | 34.32 | 502 / 504 |
| thymus | 100% | 1673.28 | 653 / 653 | 99% | 22.83 | 601 / 605 |
| brain | 99% | 1095.82 | 2624 / 2642 | 100% | 32.09 | 705 / 705 |
| kidney | 100% | 1539.34 | 89 / 89 | 99% | 24.77 | 891 / 901 |
| pancreas | 100% | 990.03 | 328 / 328 | 99% | 25.49 | 176 / 178 |
| liver | 100% | 1277.23 | 226 / 226 | 97% | 16.09 | 394 / 406 |
| adrenal gland | 100% | 1997.50 | 258 / 258 | 97% | 29.60 | 223 / 230 |
| adipose | 100% | 1671.56 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1337.33 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 43.59 | 29 / 29 |
| muscle | 100% | 1480.84 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1701.20 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 49.68 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 15.96 | 1 / 1 |
| heart | 98% | 940.92 | 844 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 23.42 | 78 / 80 |
| peripheral blood | 97% | 1565.79 | 903 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000398 | Biological process | mRNA splicing, via spliceosome |
| GO_0008380 | Biological process | RNA splicing |
| GO_0000375 | Biological process | RNA splicing, via transesterification reactions |
| GO_0006396 | Biological process | RNA processing |
| GO_0015030 | Cellular component | Cajal body |
| GO_0097525 | Cellular component | spliceosomal snRNP complex |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0046540 | Cellular component | U4/U6 x U5 tri-snRNP complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0071001 | Cellular component | U4/U6 snRNP |
| GO_0005681 | Cellular component | spliceosomal complex |
| GO_0071005 | Cellular component | U2-type precatalytic spliceosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0017070 | Molecular function | U6 snRNA binding |
| GO_0030621 | Molecular function | U4 snRNA binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PRPF4 |
| Protein name | U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) 60 kDa U4/U6 snRNP-specific spliceosomal protein (PRP4 pre-mRNA processing factor 4 homolog (Yeast), isoform CRA_b) PRPF4 protein |
| Synonyms | hCG_29193 PRP4 |
| Description | FUNCTION: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). . |
| Accessions | Q5T1M7 ENST00000374198.5 [O43172-2] O43172 ENST00000374199.9 [O43172-1] Q6IAP9 |