LSM1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	21 studies	20% ± 5%	Explore
CD8-positive, alpha-beta T cell	9 studies	21% ± 6%	Explore
plasmacytoid dendritic cell	9 studies	24% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	21% ± 2%	Explore
fibroblast	8 studies	22% ± 10%	Explore
endothelial cell	8 studies	24% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	7 studies	19% ± 3%	Explore
mature NK T cell	7 studies	17% ± 2%	Explore
gamma-delta T cell	7 studies	24% ± 15%	Explore
CD4-positive, alpha-beta T cell	6 studies	20% ± 4%	Explore
smooth muscle cell	6 studies	19% ± 3%	Explore
ciliated cell	6 studies	34% ± 10%	Explore
epithelial cell	6 studies	36% ± 20%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	17% ± 1%	Explore
platelet	5 studies	20% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	21% ± 6%	Explore
regulatory T cell	5 studies	18% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	21% ± 8%	Explore
plasma cell	4 studies	23% ± 9%	Explore
plasmablast	4 studies	39% ± 18%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
B cell	4 studies	22% ± 7%	Explore
classical monocyte	4 studies	26% ± 7%	Explore
non-classical monocyte	4 studies	28% ± 9%	Explore
pericyte	4 studies	20% ± 4%	Explore
innate lymphoid cell	4 studies	18% ± 2%	Explore
basal cell	4 studies	30% ± 14%	Explore
pancreatic A cell	3 studies	32% ± 5%	Explore
conventional dendritic cell	3 studies	36% ± 9%	Explore
hematopoietic precursor cell	3 studies	25% ± 7%	Explore
mucosal invariant T cell	3 studies	17% ± 1%	Explore
precursor B cell	3 studies	23% ± 8%	Explore
erythroblast	3 studies	30% ± 18%	Explore
dendritic cell	3 studies	40% ± 15%	Explore
goblet cell	3 studies	21% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	19% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	5 studies	21% ± 6%	Explore
lung	4 studies	29% ± 9%	Explore
pancreas	3 studies	33% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	710.60	1445 / 1445	100%	17.75	183 / 183
stomach	100%	569.97	359 / 359	100%	21.52	286 / 286
breast	100%	661.28	459 / 459	100%	32.89	1117 / 1118
brain	100%	532.95	2637 / 2642	100%	24.02	705 / 705
ovary	100%	535.72	180 / 180	100%	21.53	429 / 430
intestine	100%	695.19	966 / 966	99%	20.92	524 / 527
prostate	100%	627.76	245 / 245	99%	18.97	499 / 502
lung	99%	523.98	574 / 578	100%	25.19	1155 / 1155
pancreas	100%	367.46	327 / 328	99%	19.05	177 / 178
uterus	100%	653.89	170 / 170	99%	23.56	455 / 459
thymus	100%	552.03	653 / 653	99%	19.39	599 / 605
bladder	100%	638.76	21 / 21	99%	22.62	499 / 504
skin	100%	741.93	1809 / 1809	99%	22.63	467 / 472
kidney	100%	728.97	89 / 89	98%	15.36	885 / 901
adrenal gland	100%	778.59	258 / 258	97%	17.06	222 / 230
liver	100%	374.88	225 / 226	92%	11.08	374 / 406
adipose	100%	692.15	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	22.65	80 / 80
lymph node	0%	0	0 / 0	100%	20.66	29 / 29
spleen	100%	546.47	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	19.85	45 / 45
ureter	0%	0	0 / 0	100%	21.62	1 / 1
blood vessel	100%	842.71	1334 / 1335	0%	0	0 / 0
muscle	100%	508.59	801 / 803	0%	0	0 / 0
heart	98%	710.27	840 / 861	0%	0	0 / 0
peripheral blood	82%	358.94	761 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006397	Biological process	mRNA processing
GO_0000290	Biological process	deadenylation-dependent decapping of nuclear-transcribed mRNA
GO_0071044	Biological process	histone mRNA catabolic process
GO_0030182	Biological process	neuron differentiation
GO_0045665	Biological process	negative regulation of neuron differentiation
GO_0008380	Biological process	RNA splicing
GO_0019827	Biological process	stem cell population maintenance
GO_0000375	Biological process	RNA splicing, via transesterification reactions
GO_1990726	Cellular component	Lsm1-7-Pat1 complex
GO_0043025	Cellular component	neuronal cell body
GO_0030425	Cellular component	dendrite
GO_0000932	Cellular component	P-body
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0030424	Cellular component	axon
GO_1990904	Cellular component	ribonucleoprotein complex
GO_0005634	Cellular component	nucleus
GO_0003729	Molecular function	mRNA binding
GO_0003723	Molecular function	RNA binding
GO_0036002	Molecular function	pre-mRNA binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	LSM1
Protein name	U6 snRNA-associated Sm-like protein LSm1 LSM1 homolog, mRNA degradation associated (LSM1-like protein U6 small nuclear RNA associated isoform 3) U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm) LSM1 homolog, mRNA degradation associated
Synonyms	CASM
Description	FUNCTION: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated . Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity). . FUNCTION: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. .
Accessions	E5RJ47 ENST00000520755.5 ENST00000311351.9 O15116 A0A0S2Z590 E5RH18 ENST00000523511.1

LSM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review