BCAS2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	28 studies	24% ± 7%	Explore
B cell	24 studies	26% ± 6%	Explore
CD4-positive, alpha-beta T cell	22 studies	28% ± 10%	Explore
CD8-positive, alpha-beta T cell	21 studies	25% ± 7%	Explore
regulatory T cell	17 studies	29% ± 8%	Explore
T cell	16 studies	24% ± 6%	Explore
naive B cell	13 studies	24% ± 7%	Explore
smooth muscle cell	12 studies	21% ± 5%	Explore
memory B cell	12 studies	26% ± 10%	Explore
mast cell	11 studies	26% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	26% ± 7%	Explore
mature NK T cell	11 studies	25% ± 6%	Explore
macrophage	11 studies	20% ± 6%	Explore
gamma-delta T cell	11 studies	31% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	24% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	28% ± 7%	Explore
pericyte	10 studies	23% ± 7%	Explore
fibroblast	10 studies	23% ± 7%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	25% ± 7%	Explore
mucosal invariant T cell	9 studies	28% ± 8%	Explore
endothelial cell	9 studies	26% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	30% ± 10%	Explore
plasma cell	7 studies	31% ± 10%	Explore
epithelial cell	7 studies	36% ± 20%	Explore
basal cell	7 studies	28% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	33% ± 12%	Explore
conventional dendritic cell	6 studies	31% ± 11%	Explore
connective tissue cell	6 studies	19% ± 2%	Explore
T follicular helper cell	6 studies	31% ± 12%	Explore
plasmacytoid dendritic cell	6 studies	25% ± 11%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	21% ± 4%	Explore
leukocyte	5 studies	28% ± 10%	Explore
myeloid cell	5 studies	22% ± 8%	Explore
ciliated cell	5 studies	33% ± 12%	Explore
innate lymphoid cell	5 studies	28% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	25% ± 7%	Explore
non-classical monocyte	4 studies	26% ± 4%	Explore
classical monocyte	4 studies	21% ± 7%	Explore
immature B cell	4 studies	22% ± 3%	Explore
astrocyte	4 studies	22% ± 6%	Explore
retinal cone cell	4 studies	36% ± 15%	Explore
retinal rod cell	4 studies	23% ± 9%	Explore
Mueller cell	4 studies	30% ± 9%	Explore
CD4-positive helper T cell	4 studies	27% ± 13%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	32% ± 14%	Explore
endothelial cell of vascular tree	4 studies	20% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	4 studies	33% ± 13%	Explore
exhausted T cell	3 studies	25% ± 7%	Explore
retinal bipolar neuron	3 studies	33% ± 14%	Explore
retinal ganglion cell	3 studies	37% ± 18%	Explore
myofibroblast cell	3 studies	23% ± 4%	Explore
club cell	3 studies	21% ± 5%	Explore
retina horizontal cell	3 studies	27% ± 12%	Explore
chondrocyte	3 studies	19% ± 4%	Explore
abnormal cell	3 studies	25% ± 7%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	17% ± 1%	Explore
dendritic cell	3 studies	41% ± 10%	Explore
granulocyte	3 studies	25% ± 3%	Explore
monocyte	3 studies	17% ± 1%	Explore
endothelial cell of lymphatic vessel	3 studies	20% ± 6%	Explore
GABAergic neuron	3 studies	28% ± 7%	Explore
glutamatergic neuron	3 studies	37% ± 10%	Explore
goblet cell	3 studies	20% ± 4%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 14%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	20% ± 3%	Explore
double negative thymocyte	3 studies	33% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	23% ± 6%	Explore
lung	9 studies	23% ± 8%	Explore
intestine	6 studies	21% ± 5%	Explore
eye	6 studies	25% ± 9%	Explore
uterus	4 studies	22% ± 8%	Explore
brain	4 studies	26% ± 4%	Explore
kidney	3 studies	20% ± 3%	Explore
lymph node	3 studies	28% ± 9%	Explore
breast	3 studies	17% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	1628.94	459 / 459	100%	111.19	1118 / 1118
esophagus	100%	1528.73	1445 / 1445	100%	78.68	183 / 183
ovary	100%	1610.14	180 / 180	100%	94.20	430 / 430
uterus	100%	1379.61	170 / 170	100%	125.15	459 / 459
brain	100%	2200.63	2641 / 2642	100%	103.99	705 / 705
bladder	100%	1454.86	21 / 21	100%	94.60	503 / 504
prostate	100%	1456.71	245 / 245	100%	103.76	501 / 502
thymus	100%	1484.18	653 / 653	100%	94.25	603 / 605
stomach	100%	1174.64	359 / 359	100%	74.73	285 / 286
intestine	100%	1439.02	966 / 966	100%	75.23	525 / 527
liver	100%	1080.19	226 / 226	99%	60.33	403 / 406
lung	99%	1291.92	573 / 578	100%	94.00	1155 / 1155
pancreas	99%	728.41	326 / 328	99%	72.15	177 / 178
kidney	100%	1458.97	89 / 89	99%	65.77	889 / 901
adrenal gland	100%	1712.33	258 / 258	98%	84.41	226 / 230
skin	100%	1678.46	1809 / 1809	97%	83.06	456 / 472
adipose	100%	1570.60	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1716.94	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	89.45	29 / 29
muscle	100%	1583.46	803 / 803	0%	0	0 / 0
spleen	100%	1144.43	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	115.70	45 / 45
ureter	0%	0	0 / 0	100%	44.12	1 / 1
heart	97%	1266.58	838 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	85%	37.92	68 / 80
peripheral blood	81%	851.89	753 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0008380	Biological process	RNA splicing
GO_0000375	Biological process	RNA splicing, via transesterification reactions
GO_0016607	Cellular component	nuclear speck
GO_0005813	Cellular component	centrosome
GO_0005730	Cellular component	nucleolus
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0005654	Cellular component	nucleoplasm
GO_0005662	Cellular component	DNA replication factor A complex
GO_0071007	Cellular component	U2-type catalytic step 2 spliceosome
GO_0005681	Cellular component	spliceosomal complex
GO_0000974	Cellular component	Prp19 complex
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	BCAS2
Protein name	Pre-mRNA-splicing factor SPF27 Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)
Synonyms	DAM1 hCG_38455
Description	FUNCTION: Required for pre-mRNA splicing as component of the activated spliceosome . Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). .
Accessions	O75934 B2R7W3 ENST00000369541.4

BCAS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review