SRRM1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	42 studies	37% ± 13%	Explore
fibroblast	40 studies	34% ± 12%	Explore
natural killer cell	38 studies	46% ± 16%	Explore
B cell	37 studies	47% ± 12%	Explore
CD8-positive, alpha-beta T cell	35 studies	45% ± 15%	Explore
macrophage	34 studies	36% ± 11%	Explore
T cell	33 studies	40% ± 13%	Explore
pericyte	33 studies	35% ± 12%	Explore
CD4-positive, alpha-beta T cell	30 studies	47% ± 15%	Explore
smooth muscle cell	29 studies	36% ± 12%	Explore
conventional dendritic cell	28 studies	51% ± 16%	Explore
classical monocyte	25 studies	46% ± 15%	Explore
regulatory T cell	25 studies	48% ± 11%	Explore
non-classical monocyte	23 studies	49% ± 16%	Explore
endothelial cell of lymphatic vessel	21 studies	37% ± 11%	Explore
plasmacytoid dendritic cell	21 studies	49% ± 16%	Explore
epithelial cell	21 studies	43% ± 19%	Explore
dendritic cell	20 studies	46% ± 25%	Explore
mast cell	20 studies	40% ± 17%	Explore
monocyte	20 studies	40% ± 12%	Explore
mature NK T cell	20 studies	42% ± 13%	Explore
memory B cell	20 studies	50% ± 12%	Explore
naive B cell	20 studies	44% ± 14%	Explore
basal cell	20 studies	41% ± 16%	Explore
gamma-delta T cell	18 studies	51% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	45% ± 16%	Explore
ciliated cell	17 studies	41% ± 18%	Explore
connective tissue cell	16 studies	38% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	50% ± 18%	Explore
mucosal invariant T cell	15 studies	49% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	51% ± 14%	Explore
myeloid cell	15 studies	43% ± 19%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	52% ± 13%	Explore
myofibroblast cell	14 studies	37% ± 12%	Explore
oligodendrocyte	14 studies	36% ± 15%	Explore
astrocyte	14 studies	32% ± 12%	Explore
plasma cell	13 studies	37% ± 13%	Explore
capillary endothelial cell	13 studies	33% ± 9%	Explore
vein endothelial cell	13 studies	34% ± 8%	Explore
endothelial cell of vascular tree	13 studies	35% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	49% ± 20%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	51% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	53% ± 14%	Explore
type I pneumocyte	11 studies	31% ± 14%	Explore
secretory cell	11 studies	45% ± 16%	Explore
microglial cell	11 studies	30% ± 10%	Explore
type II pneumocyte	10 studies	32% ± 12%	Explore
plasmablast	10 studies	54% ± 22%	Explore
progenitor cell	10 studies	41% ± 17%	Explore
endothelial cell of artery	10 studies	36% ± 7%	Explore
oligodendrocyte precursor cell	10 studies	30% ± 13%	Explore
club cell	9 studies	35% ± 12%	Explore
leukocyte	9 studies	43% ± 15%	Explore
goblet cell	9 studies	31% ± 15%	Explore
mesothelial cell	9 studies	38% ± 16%	Explore
innate lymphoid cell	8 studies	41% ± 14%	Explore
glutamatergic neuron	8 studies	37% ± 22%	Explore
abnormal cell	8 studies	43% ± 13%	Explore
neuron	8 studies	38% ± 17%	Explore
alveolar macrophage	7 studies	33% ± 8%	Explore
respiratory goblet cell	7 studies	31% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	54% ± 13%	Explore
amacrine cell	7 studies	40% ± 18%	Explore
retinal rod cell	7 studies	35% ± 14%	Explore
hematopoietic stem cell	7 studies	57% ± 10%	Explore
precursor B cell	7 studies	52% ± 12%	Explore
immature B cell	7 studies	51% ± 9%	Explore
adipocyte	7 studies	22% ± 5%	Explore
T follicular helper cell	7 studies	46% ± 12%	Explore
GABAergic neuron	7 studies	34% ± 16%	Explore
hematopoietic precursor cell	6 studies	54% ± 23%	Explore
ionocyte	6 studies	36% ± 12%	Explore
platelet	6 studies	25% ± 5%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	47% ± 15%	Explore
mononuclear phagocyte	6 studies	43% ± 15%	Explore
interneuron	6 studies	34% ± 20%	Explore
lymphocyte	6 studies	43% ± 19%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	57% ± 14%	Explore
CD4-positive helper T cell	5 studies	40% ± 18%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	49% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	41% ± 11%	Explore
exhausted T cell	5 studies	50% ± 12%	Explore
kidney loop of Henle epithelial cell	5 studies	28% ± 5%	Explore
enterocyte	5 studies	23% ± 5%	Explore
transit amplifying cell	5 studies	38% ± 13%	Explore
glial cell	5 studies	31% ± 16%	Explore
pro-B cell	5 studies	53% ± 13%	Explore
brush cell	5 studies	35% ± 18%	Explore
retina horizontal cell	5 studies	40% ± 16%	Explore
retinal cone cell	5 studies	46% ± 19%	Explore
Mueller cell	5 studies	47% ± 15%	Explore
granulocyte	5 studies	40% ± 4%	Explore
erythrocyte	5 studies	45% ± 19%	Explore
deuterosomal cell	4 studies	31% ± 8%	Explore
duct epithelial cell	4 studies	32% ± 3%	Explore
pancreatic A cell	4 studies	49% ± 12%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	42% ± 10%	Explore
epithelial cell of proximal tubule	4 studies	24% ± 10%	Explore
renal alpha-intercalated cell	4 studies	36% ± 9%	Explore
enteroendocrine cell	4 studies	39% ± 10%	Explore
retinal bipolar neuron	4 studies	47% ± 20%	Explore
adventitial cell	4 studies	23% ± 8%	Explore
cardiac muscle cell	4 studies	23% ± 4%	Explore
intermediate monocyte	4 studies	56% ± 20%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	43% ± 7%	Explore
myoepithelial cell	4 studies	35% ± 5%	Explore
T-helper 17 cell	4 studies	45% ± 15%	Explore
double negative thymocyte	4 studies	66% ± 10%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	39% ± 10%	Explore
precursor cell	3 studies	55% ± 7%	Explore
squamous epithelial cell	3 studies	40% ± 26%	Explore
pancreatic D cell	3 studies	43% ± 19%	Explore
type B pancreatic cell	3 studies	53% ± 14%	Explore
glomerular endothelial cell	3 studies	36% ± 8%	Explore
intestinal crypt stem cell	3 studies	32% ± 7%	Explore
neural crest cell	3 studies	48% ± 0%	Explore
OFF-bipolar cell	3 studies	32% ± 14%	Explore
ON-bipolar cell	3 studies	35% ± 14%	Explore
retinal ganglion cell	3 studies	50% ± 16%	Explore
extravillous trophoblast	3 studies	38% ± 13%	Explore
placental villous trophoblast	3 studies	49% ± 11%	Explore
erythroblast	3 studies	67% ± 19%	Explore
neuroendocrine cell	3 studies	39% ± 16%	Explore
retinal pigment epithelial cell	3 studies	47% ± 22%	Explore
mucus secreting cell	3 studies	32% ± 7%	Explore
serous secreting cell	3 studies	32% ± 1%	Explore
tissue-resident macrophage	3 studies	33% ± 11%	Explore
rod bipolar cell	3 studies	47% ± 10%	Explore
germinal center B cell	3 studies	41% ± 4%	Explore
luminal cell of prostate epithelium	3 studies	36% ± 9%	Explore
muscle cell	3 studies	44% ± 15%	Explore
pancreatic ductal cell	3 studies	56% ± 15%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	76% ± 10%	Explore
neutrophil	3 studies	20% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	59% ± 15%	Explore
melanocyte	3 studies	39% ± 9%	Explore
keratinocyte	3 studies	36% ± 10%	Explore
T-helper 1 cell	3 studies	54% ± 6%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	58% ± 3%	Explore
double-positive, alpha-beta thymocyte	3 studies	71% ± 7%	Explore
progenitor cell of mammary luminal epithelium	3 studies	35% ± 8%	Explore
hepatocyte	3 studies	43% ± 12%	Explore
IgA plasma cell	3 studies	20% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	52% ± 13%	Explore
lung	17 studies	41% ± 13%	Explore
brain	17 studies	32% ± 17%	Explore
intestine	11 studies	32% ± 14%	Explore
eye	10 studies	38% ± 15%	Explore
kidney	8 studies	32% ± 10%	Explore
lymph node	5 studies	45% ± 7%	Explore
liver	5 studies	43% ± 18%	Explore
pancreas	4 studies	44% ± 17%	Explore
bone marrow	4 studies	41% ± 15%	Explore
heart	4 studies	23% ± 5%	Explore
uterus	4 studies	53% ± 15%	Explore
breast	4 studies	39% ± 8%	Explore
adipose	4 studies	30% ± 9%	Explore
placenta	3 studies	42% ± 8%	Explore
prostate	3 studies	38% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	8413.30	1445 / 1445	100%	71.46	183 / 183
ovary	100%	17434.52	180 / 180	100%	39.65	430 / 430
prostate	100%	12108.03	245 / 245	100%	51.73	502 / 502
breast	100%	10725.83	459 / 459	100%	42.71	1116 / 1118
bladder	100%	9276.14	21 / 21	100%	37.64	503 / 504
uterus	100%	15820.19	170 / 170	100%	42.88	458 / 459
lung	100%	8834.19	578 / 578	100%	42.12	1152 / 1155
stomach	100%	6435.50	359 / 359	100%	45.15	285 / 286
intestine	100%	9728.82	966 / 966	100%	38.58	525 / 527
thymus	100%	9519.44	653 / 653	99%	38.21	600 / 605
skin	100%	10310.97	1809 / 1809	99%	40.74	468 / 472
brain	99%	6563.67	2606 / 2642	100%	34.85	705 / 705
pancreas	100%	4089.88	327 / 328	99%	33.17	176 / 178
kidney	100%	5501.19	89 / 89	97%	27.67	877 / 901
adrenal gland	100%	6444.54	258 / 258	96%	20.21	220 / 230
liver	100%	3316.87	226 / 226	91%	15.25	369 / 406
adipose	100%	9065.46	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	38.13	29 / 29
muscle	100%	6948.11	803 / 803	0%	0	0 / 0
spleen	100%	9128.52	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	40.70	45 / 45
ureter	0%	0	0 / 0	100%	9.50	1 / 1
blood vessel	100%	8713.19	1334 / 1335	0%	0	0 / 0
heart	98%	5452.85	845 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	23.64	78 / 80
peripheral blood	82%	5006.22	766 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	SRRM1
Protein name	Serine and arginine repetitive matrix 1 (Serine/arginine repetitive matrix 1 isoform 2) Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein) Serine/arginine repetitive matrix 1 isoform 1 (Serine/arginine repetitive matrix 1, isoform CRA_a) Serine and arginine repetitive matrix 1
Synonyms	hCG_96287 SRM160
Description	FUNCTION: Part of pre- and post-splicing multiprotein mRNP complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates. .
Accessions	Q8IYB3 ENST00000705663.1 ENST00000374389.8 M0R088 A9Z1X7 M0QXG5 ENST00000705662.1 ENST00000600523.5 A0A994J7H1 M0R1E7 A0A0S2Z4Z6 A0A994J7V4 ENST00000323848.14 [Q8IYB3-1] ENST00000705681.1 ENST00000705682.1 A0A0S2Z4W1 A0A994J4Y3 ENST00000593639.5 ENST00000596378.1

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0008380	Biological process	RNA splicing
GO_0000375	Biological process	RNA splicing, via transesterification reactions
GO_0048024	Biological process	regulation of mRNA splicing, via spliceosome
GO_0016363	Cellular component	nuclear matrix
GO_0016607	Cellular component	nuclear speck
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005681	Cellular component	spliceosomal complex
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

SRRM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review