RBM10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1905461Biological processpositive regulation of vascular associated smooth muscle cell apoptotic process
GO_2000204Biological processnegative regulation of ribosomal large subunit export from nucleus
GO_1904706Biological processnegative regulation of vascular associated smooth muscle cell proliferation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0008150Biological processbiological_process
GO_0000398Biological processmRNA splicing, via spliceosome
GO_1905288Biological processvascular associated smooth muscle cell apoptotic process
GO_1990874Biological processvascular associated smooth muscle cell proliferation
GO_0070935Biological process3'-UTR-mediated mRNA stabilization
GO_0048025Biological processnegative regulation of mRNA splicing, via spliceosome
GO_0005730Cellular componentnucleolus
GO_0016607Cellular componentnuclear speck
GO_0032991Cellular componentprotein-containing complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0042802Molecular functionidentical protein binding
GO_0046872Molecular functionmetal ion binding
GO_0003723Molecular functionRNA binding
GO_0035198Molecular functionmiRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRBM10
Protein nameRNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1)
Epididymis secretory sperm binding protein (RNA binding motif protein 10 isoform 1)
RBM10 protein
RNA binding motif protein 10 isoform 2
Ribosome biogenesis inhibitor MINAS-60 (MINAS-60)
SynonymsGPATC9
GPATCH9
DXS8237E
KIAA0122
DescriptionFUNCTION: May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins . .

FUNCTION: Acts as a late-stage inhibitor of pre-60S ribosome assembly by preventing pre-60S ribosome export from nucleus. .

AccessionsQ6PKH5
P0DW28
A0A0S2Z4W4
ENST00000345781.10 [P98175-3]
ENST00000377604.8 [P98175-1]
A0A0S2Z4X1
ENST00000628161.2 [P98175-4]
P98175
ENST00000329236.8 [P98175-5]