SNU13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042274Biological processribosomal small subunit biogenesis
GO_0000398Biological processmRNA splicing, via spliceosome
GO_0000492Biological processbox C/D snoRNP assembly
GO_0030490Biological processmaturation of SSU-rRNA
GO_0007338Biological processsingle fertilization
GO_0046540Cellular componentU4/U6 x U5 tri-snRNP complex
GO_0005730Cellular componentnucleolus
GO_0001651Cellular componentdense fibrillar component
GO_0032040Cellular componentsmall-subunit processome
GO_0032991Cellular componentprotein-containing complex
GO_0005654Cellular componentnucleoplasm
GO_0005690Cellular componentU4atac snRNP
GO_0071005Cellular componentU2-type precatalytic spliceosome
GO_0071011Cellular componentprecatalytic spliceosome
GO_0031428Cellular componentbox C/D methylation guide snoRNP complex
GO_0005634Cellular componentnucleus
GO_0034511Molecular functionU3 snoRNA binding
GO_0030622Molecular functionU4atac snRNA binding
GO_0034512Molecular functionbox C/D sno(s)RNA binding
GO_0030515Molecular functionsnoRNA binding
GO_0003723Molecular functionRNA binding
GO_0051117Molecular functionATPase binding
GO_0030621Molecular functionU4 snRNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSNU13
Protein nameNHP2-like protein 1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae), isoform CRA_b (Small nuclear ribonucleoprotein 13)
Small nuclear ribonucleoprotein 13
NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (OTK27) (SNU13 homolog) (hSNU13) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed]
SynonymsNHP2L1
hCG_41538
DescriptionFUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome . Involved in pre-mRNA splicing as component of the spliceosome . Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly . The protein undergoes a conformational change upon RNA-binding . .

FUNCTION: Common component of the spliceosome and rRNA processing machinery. .; FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. .

FUNCTION: Common component of the spliceosome and rRNA processing machinery. .; FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. .

FUNCTION: Common component of the spliceosome and rRNA processing machinery. .; FUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. .

AccessionsA0A3B3ISH9
Q6FHM6
ENST00000463675.6
ENST00000401959.6
ENST00000649479.1
ENST00000648674.1
A0A3B3ISH1
ENST00000648350.1
A0A3B3IUA2
A0A3B3ISK4
B1AHD1
ENST00000402458.1
ENST00000469522.1
A0A3B3IRU2
ENST00000215956.10
P55769
ENST00000469028.2
ENST00000649722.1