ZMAT2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	27 studies	23% ± 6%	Explore
regulatory T cell	18 studies	23% ± 4%	Explore
CD8-positive, alpha-beta T cell	17 studies	22% ± 6%	Explore
B cell	15 studies	21% ± 6%	Explore
classical monocyte	14 studies	26% ± 10%	Explore
CD4-positive, alpha-beta T cell	14 studies	21% ± 5%	Explore
gamma-delta T cell	14 studies	24% ± 11%	Explore
naive B cell	13 studies	20% ± 4%	Explore
ciliated cell	12 studies	30% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	22% ± 5%	Explore
non-classical monocyte	11 studies	26% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	22% ± 4%	Explore
memory B cell	11 studies	19% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	24% ± 4%	Explore
T cell	10 studies	20% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	20% ± 3%	Explore
mature NK T cell	9 studies	21% ± 2%	Explore
macrophage	9 studies	24% ± 9%	Explore
monocyte	9 studies	22% ± 7%	Explore
endothelial cell	9 studies	28% ± 9%	Explore
mucosal invariant T cell	9 studies	19% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	9 studies	23% ± 7%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	21% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	23% ± 4%	Explore
fibroblast	7 studies	28% ± 8%	Explore
epithelial cell	7 studies	41% ± 18%	Explore
mast cell	6 studies	18% ± 1%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	22% ± 4%	Explore
conventional dendritic cell	6 studies	30% ± 14%	Explore
myofibroblast cell	6 studies	19% ± 4%	Explore
smooth muscle cell	6 studies	21% ± 4%	Explore
pericyte	6 studies	21% ± 5%	Explore
T follicular helper cell	6 studies	19% ± 3%	Explore
plasmacytoid dendritic cell	6 studies	25% ± 9%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	21% ± 7%	Explore
erythrocyte	5 studies	31% ± 21%	Explore
exhausted T cell	4 studies	27% ± 5%	Explore
neuron	4 studies	27% ± 13%	Explore
precursor B cell	4 studies	27% ± 9%	Explore
endothelial cell of lymphatic vessel	4 studies	22% ± 8%	Explore
pro-B cell	4 studies	23% ± 3%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	24% ± 3%	Explore
endothelial cell of vascular tree	4 studies	18% ± 2%	Explore
innate lymphoid cell	4 studies	21% ± 2%	Explore
pancreatic A cell	3 studies	30% ± 10%	Explore
hematopoietic precursor cell	3 studies	31% ± 8%	Explore
capillary endothelial cell	3 studies	17% ± 1%	Explore
kidney loop of Henle epithelial cell	3 studies	18% ± 0%	Explore
connective tissue cell	3 studies	23% ± 4%	Explore
epithelial cell of proximal tubule	3 studies	21% ± 3%	Explore
neural crest cell	3 studies	17% ± 1%	Explore
basal cell	3 studies	33% ± 12%	Explore
immature B cell	3 studies	19% ± 3%	Explore
germinal center B cell	3 studies	18% ± 1%	Explore
GABAergic neuron	3 studies	25% ± 6%	Explore
glutamatergic neuron	3 studies	40% ± 6%	Explore
goblet cell	3 studies	21% ± 5%	Explore
intestinal crypt stem cell	3 studies	19% ± 1%	Explore
endothelial cell of artery	3 studies	16% ± 1%	Explore
erythroblast	3 studies	37% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	20% ± 4%	Explore
double negative thymocyte	3 studies	32% ± 16%	Explore
hematopoietic stem cell	3 studies	20% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	14 studies	23% ± 7%	Explore
lung	8 studies	25% ± 5%	Explore
kidney	4 studies	19% ± 3%	Explore
pancreas	3 studies	32% ± 10%	Explore
bone marrow	3 studies	19% ± 3%	Explore
eye	3 studies	21% ± 6%	Explore
lymph node	3 studies	22% ± 7%	Explore
brain	3 studies	27% ± 4%	Explore
liver	3 studies	33% ± 23%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	4942.22	2642 / 2642	100%	210.96	705 / 705
esophagus	100%	3828.99	1445 / 1445	100%	78.76	183 / 183
intestine	100%	3699.85	966 / 966	100%	124.21	527 / 527
liver	100%	2064.33	226 / 226	100%	127.77	406 / 406
lung	100%	3371.63	578 / 578	100%	137.42	1155 / 1155
ovary	100%	3350.62	180 / 180	100%	108.83	430 / 430
stomach	100%	2930.99	359 / 359	100%	96.47	286 / 286
uterus	100%	3787.94	170 / 170	100%	180.36	459 / 459
kidney	100%	3714.99	89 / 89	100%	162.90	900 / 901
thymus	100%	3484.30	653 / 653	100%	188.79	604 / 605
breast	100%	3903.92	459 / 459	100%	190.30	1116 / 1118
bladder	100%	3632.43	21 / 21	100%	141.93	503 / 504
prostate	100%	3248.22	245 / 245	100%	136.98	501 / 502
skin	100%	4298.75	1809 / 1809	100%	146.99	471 / 472
pancreas	99%	1609.54	324 / 328	100%	151.95	178 / 178
adrenal gland	100%	3961.64	258 / 258	98%	135.83	225 / 230
adipose	100%	3801.92	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4178.97	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	146.74	80 / 80
lymph node	0%	0	0 / 0	100%	182.88	29 / 29
muscle	100%	4096.85	803 / 803	0%	0	0 / 0
spleen	100%	4176.06	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	170.43	45 / 45
ureter	0%	0	0 / 0	100%	51.58	1 / 1
peripheral blood	100%	4560.37	926 / 929	0%	0	0 / 0
heart	98%	2207.47	841 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0