Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 18 studies | 27% ± 9% | |
brain | 17 studies | 30% ± 15% | |
peripheral blood | 16 studies | 32% ± 10% | |
intestine | 9 studies | 24% ± 10% | |
eye | 8 studies | 30% ± 11% | |
kidney | 6 studies | 24% ± 5% | |
lymph node | 5 studies | 29% ± 12% | |
liver | 5 studies | 39% ± 18% | |
bone marrow | 4 studies | 27% ± 5% | |
heart | 4 studies | 21% ± 3% | |
uterus | 4 studies | 30% ± 16% | |
adipose | 4 studies | 34% ± 9% | |
pancreas | 3 studies | 43% ± 6% | |
placenta | 3 studies | 20% ± 2% | |
breast | 3 studies | 23% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3708.65 | 1445 / 1445 | 100% | 34.80 | 183 / 183 |
intestine | 100% | 4174.06 | 966 / 966 | 100% | 26.38 | 527 / 527 |
lung | 100% | 3982.64 | 578 / 578 | 100% | 24.42 | 1155 / 1155 |
ovary | 100% | 4112.43 | 180 / 180 | 100% | 23.40 | 430 / 430 |
uterus | 100% | 4716.85 | 170 / 170 | 100% | 27.48 | 459 / 459 |
breast | 100% | 4337.83 | 459 / 459 | 100% | 33.35 | 1117 / 1118 |
bladder | 100% | 3868.90 | 21 / 21 | 100% | 22.49 | 502 / 504 |
prostate | 100% | 3582.01 | 245 / 245 | 100% | 21.86 | 500 / 502 |
pancreas | 100% | 2497.54 | 328 / 328 | 99% | 21.46 | 177 / 178 |
stomach | 100% | 3245.83 | 359 / 359 | 99% | 27.76 | 284 / 286 |
thymus | 100% | 4078.25 | 653 / 653 | 99% | 20.97 | 598 / 605 |
brain | 99% | 2405.81 | 2606 / 2642 | 100% | 23.23 | 705 / 705 |
skin | 100% | 4904.53 | 1809 / 1809 | 97% | 22.97 | 459 / 472 |
kidney | 100% | 2757.29 | 89 / 89 | 97% | 17.95 | 874 / 901 |
liver | 100% | 2133.23 | 226 / 226 | 97% | 13.15 | 392 / 406 |
adrenal gland | 100% | 3521.87 | 258 / 258 | 96% | 14.99 | 220 / 230 |
adipose | 100% | 4053.59 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3899.12 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 28.47 | 29 / 29 |
muscle | 100% | 4655.24 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 4784.88 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 30.87 | 45 / 45 |
heart | 97% | 2163.58 | 834 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 94% | 3029.96 | 872 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 11.62 | 72 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0000398 | Biological process | mRNA splicing, via spliceosome |
GO_1903241 | Biological process | U2-type prespliceosome assembly |
GO_0005686 | Cellular component | U2 snRNP |
GO_0015030 | Cellular component | Cajal body |
GO_0016607 | Cellular component | nuclear speck |
GO_0001650 | Cellular component | fibrillar center |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005681 | Cellular component | spliceosomal complex |
GO_0005684 | Cellular component | U2-type spliceosomal complex |
GO_0005634 | Cellular component | nucleus |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0003724 | Molecular function | RNA helicase activity |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | DDX46 |
Protein name | DEAD-box helicase 46 RNA helicase (EC 3.6.4.13) ATP-dependent RNA helicase (EC 3.6.4.13) DDX46 protein Probable ATP-dependent RNA helicase DDX46 (EC 3.6.4.13) (DEAD box protein 46) (PRP5 homolog) |
Synonyms | KIAA0801 hCG_16595 |
Description | FUNCTION: Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs . The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing . Within the 17S U2 SnRNP complex, DDX46 plays essential roles during assembly of pre-spliceosome and proofreading of the branch site . . FUNCTION: RNA helicase. . |
Accessions | A0A0C4DG89 H0YAD5 D6RJA6 H0Y9U3 ENST00000513592.5 Q0VGL8 ENST00000507392.5 ENST00000354283.8 ENST00000452510.7 ENST00000628477.2 Q7L014 ENST00000507053.1 |