SRRM2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	45 studies	43% ± 17%	Explore
endothelial cell	45 studies	48% ± 16%	Explore
fibroblast	44 studies	48% ± 16%	Explore
macrophage	39 studies	43% ± 16%	Explore
natural killer cell	39 studies	40% ± 16%	Explore
pericyte	38 studies	50% ± 15%	Explore
CD8-positive, alpha-beta T cell	34 studies	36% ± 14%	Explore
T cell	33 studies	37% ± 14%	Explore
CD4-positive, alpha-beta T cell	33 studies	37% ± 16%	Explore
smooth muscle cell	31 studies	46% ± 15%	Explore
classical monocyte	27 studies	43% ± 19%	Explore
conventional dendritic cell	27 studies	42% ± 16%	Explore
dendritic cell	24 studies	46% ± 23%	Explore
regulatory T cell	24 studies	36% ± 12%	Explore
endothelial cell of lymphatic vessel	23 studies	45% ± 15%	Explore
non-classical monocyte	23 studies	46% ± 19%	Explore
basal cell	23 studies	48% ± 17%	Explore
epithelial cell	23 studies	46% ± 20%	Explore
mast cell	22 studies	43% ± 20%	Explore
plasmacytoid dendritic cell	22 studies	53% ± 16%	Explore
monocyte	21 studies	44% ± 15%	Explore
ciliated cell	20 studies	58% ± 19%	Explore
memory B cell	20 studies	43% ± 15%	Explore
naive B cell	20 studies	39% ± 17%	Explore
gamma-delta T cell	19 studies	43% ± 19%	Explore
mature NK T cell	19 studies	36% ± 12%	Explore
astrocyte	19 studies	41% ± 16%	Explore
plasma cell	18 studies	43% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	37% ± 17%	Explore
connective tissue cell	17 studies	49% ± 13%	Explore
oligodendrocyte	17 studies	36% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	42% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	43% ± 18%	Explore
myeloid cell	16 studies	48% ± 15%	Explore
mucosal invariant T cell	15 studies	37% ± 14%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	39% ± 17%	Explore
oligodendrocyte precursor cell	15 studies	42% ± 16%	Explore
myofibroblast cell	15 studies	48% ± 14%	Explore
capillary endothelial cell	14 studies	40% ± 9%	Explore
microglial cell	14 studies	48% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	45% ± 23%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	40% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	44% ± 13%	Explore
vein endothelial cell	13 studies	43% ± 11%	Explore
endothelial cell of vascular tree	13 studies	46% ± 14%	Explore
type I pneumocyte	12 studies	52% ± 17%	Explore
secretory cell	12 studies	52% ± 16%	Explore
endothelial cell of artery	12 studies	41% ± 12%	Explore
mesothelial cell	12 studies	45% ± 17%	Explore
type II pneumocyte	11 studies	51% ± 17%	Explore
plasmablast	11 studies	52% ± 23%	Explore
club cell	11 studies	45% ± 13%	Explore
glutamatergic neuron	11 studies	44% ± 20%	Explore
leukocyte	10 studies	45% ± 15%	Explore
progenitor cell	10 studies	45% ± 13%	Explore
abnormal cell	10 studies	47% ± 15%	Explore
neuron	10 studies	47% ± 17%	Explore
GABAergic neuron	9 studies	41% ± 18%	Explore
goblet cell	9 studies	41% ± 18%	Explore
adipocyte	9 studies	48% ± 13%	Explore
alveolar macrophage	8 studies	42% ± 15%	Explore
innate lymphoid cell	8 studies	38% ± 12%	Explore
respiratory goblet cell	8 studies	51% ± 10%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	35% ± 13%	Explore
amacrine cell	7 studies	49% ± 17%	Explore
retinal rod cell	7 studies	35% ± 8%	Explore
interneuron	7 studies	50% ± 19%	Explore
precursor B cell	7 studies	44% ± 13%	Explore
T follicular helper cell	7 studies	39% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	27% ± 4%	Explore
hematopoietic precursor cell	6 studies	53% ± 20%	Explore
ionocyte	6 studies	45% ± 13%	Explore
neutrophil	6 studies	25% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	31% ± 15%	Explore
mononuclear phagocyte	6 studies	45% ± 15%	Explore
erythrocyte	6 studies	37% ± 17%	Explore
IgA plasma cell	6 studies	29% ± 13%	Explore
retina horizontal cell	6 studies	55% ± 17%	Explore
retinal ganglion cell	6 studies	57% ± 19%	Explore
lymphocyte	6 studies	48% ± 16%	Explore
retinal cone cell	6 studies	43% ± 18%	Explore
mucus secreting cell	6 studies	39% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	51% ± 22%	Explore
hepatocyte	6 studies	56% ± 28%	Explore
CD4-positive helper T cell	5 studies	40% ± 22%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	39% ± 18%	Explore
exhausted T cell	5 studies	44% ± 18%	Explore
renal alpha-intercalated cell	5 studies	31% ± 12%	Explore
enterocyte	5 studies	28% ± 5%	Explore
enteroendocrine cell	5 studies	43% ± 13%	Explore
IgG plasma cell	5 studies	30% ± 9%	Explore
transit amplifying cell	5 studies	45% ± 19%	Explore
glial cell	5 studies	43% ± 16%	Explore
kidney loop of Henle epithelial cell	5 studies	28% ± 8%	Explore
hematopoietic stem cell	5 studies	48% ± 18%	Explore
pro-B cell	5 studies	43% ± 14%	Explore
brush cell	5 studies	42% ± 15%	Explore
immature B cell	5 studies	42% ± 6%	Explore
adventitial cell	5 studies	45% ± 6%	Explore
cardiac muscle cell	5 studies	40% ± 14%	Explore
Mueller cell	5 studies	34% ± 9%	Explore
deuterosomal cell	4 studies	50% ± 14%	Explore
duct epithelial cell	4 studies	46% ± 16%	Explore
precursor cell	4 studies	41% ± 20%	Explore
squamous epithelial cell	4 studies	50% ± 18%	Explore
platelet	4 studies	35% ± 15%	Explore
pancreatic A cell	4 studies	58% ± 19%	Explore
type B pancreatic cell	4 studies	49% ± 24%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	41% ± 12%	Explore
epithelial cell of proximal tubule	4 studies	44% ± 15%	Explore
intestinal crypt stem cell	4 studies	28% ± 8%	Explore
retinal bipolar neuron	4 studies	50% ± 13%	Explore
granule cell	4 studies	34% ± 10%	Explore
erythroblast	4 studies	55% ± 23%	Explore
retinal pigment epithelial cell	4 studies	49% ± 14%	Explore
intermediate monocyte	4 studies	53% ± 26%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	54% ± 11%	Explore
myoepithelial cell	4 studies	48% ± 16%	Explore
granulocyte	4 studies	38% ± 14%	Explore
luminal cell of prostate epithelium	4 studies	40% ± 11%	Explore
muscle cell	4 studies	43% ± 20%	Explore
keratinocyte	4 studies	41% ± 12%	Explore
T-helper 17 cell	4 studies	37% ± 5%	Explore
double negative thymocyte	4 studies	53% ± 19%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	31% ± 8%	Explore
hillock cell	3 studies	34% ± 9%	Explore
pancreatic D cell	3 studies	58% ± 23%	Explore
monocyte-derived dendritic cell	3 studies	42% ± 25%	Explore
glomerular endothelial cell	3 studies	34% ± 4%	Explore
podocyte	3 studies	40% ± 14%	Explore
neural crest cell	3 studies	58% ± 9%	Explore
GABAergic interneuron	3 studies	37% ± 10%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	43% ± 15%	Explore
glycinergic amacrine cell	3 studies	28% ± 11%	Explore
extravillous trophoblast	3 studies	56% ± 17%	Explore
placental villous trophoblast	3 studies	62% ± 14%	Explore
tissue-resident macrophage	3 studies	52% ± 21%	Explore
OFF-bipolar cell	3 studies	41% ± 14%	Explore
ON-bipolar cell	3 studies	40% ± 12%	Explore
rod bipolar cell	3 studies	45% ± 13%	Explore
germinal center B cell	3 studies	33% ± 2%	Explore
endothelial cell of sinusoid	3 studies	23% ± 7%	Explore
pancreatic ductal cell	3 studies	60% ± 20%	Explore
neural progenitor cell	3 studies	42% ± 15%	Explore
ependymal cell	3 studies	52% ± 19%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	74% ± 8%	Explore
chondrocyte	3 studies	44% ± 8%	Explore
group 3 innate lymphoid cell	3 studies	61% ± 18%	Explore
melanocyte	3 studies	50% ± 5%	Explore
T-helper 1 cell	3 studies	39% ± 5%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	42% ± 16%	Explore
progenitor cell of mammary luminal epithelium	3 studies	47% ± 8%	Explore
mural cell	3 studies	46% ± 19%	Explore
renal principal cell	3 studies	31% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	20 studies	41% ± 19%	Explore
lung	19 studies	47% ± 15%	Explore
peripheral blood	19 studies	43% ± 18%	Explore
eye	11 studies	40% ± 16%	Explore
intestine	10 studies	39% ± 17%	Explore
kidney	9 studies	36% ± 8%	Explore
liver	6 studies	49% ± 17%	Explore
heart	5 studies	37% ± 13%	Explore
lymph node	5 studies	44% ± 11%	Explore
breast	5 studies	44% ± 15%	Explore
pancreas	4 studies	52% ± 22%	Explore
bone marrow	4 studies	45% ± 19%	Explore
uterus	4 studies	64% ± 17%	Explore
prostate	4 studies	41% ± 12%	Explore
adipose	4 studies	45% ± 10%	Explore
placenta	3 studies	56% ± 12%	Explore
esophagus	3 studies	40% ± 20%	Explore
skin	3 studies	32% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	81634.89	1445 / 1445	100%	286.12	183 / 183
intestine	100%	104271.04	966 / 966	100%	166.30	526 / 527
prostate	100%	100857.93	245 / 245	100%	172.65	501 / 502
skin	100%	76035.21	1809 / 1809	100%	152.94	471 / 472
uterus	100%	127828.56	170 / 170	100%	152.89	458 / 459
stomach	100%	87398.07	359 / 359	100%	189.39	285 / 286
pancreas	100%	69527.48	328 / 328	99%	143.53	177 / 178
bladder	100%	84295.14	21 / 21	99%	124.69	501 / 504
breast	100%	93482.99	459 / 459	99%	199.91	1111 / 1118
thymus	100%	116378.48	652 / 653	100%	149.59	602 / 605
ovary	100%	111441.24	180 / 180	99%	178.81	427 / 430
lung	100%	91704.86	578 / 578	98%	158.28	1137 / 1155
adrenal gland	100%	77355.82	258 / 258	98%	104.47	225 / 230
kidney	100%	66117.63	89 / 89	98%	130.72	880 / 901
liver	100%	48919.67	225 / 226	87%	67.57	354 / 406
brain	87%	33844.95	2306 / 2642	99%	170.81	699 / 705
adipose	100%	77532.65	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	127.44	80 / 80
lymph node	0%	0	0 / 0	100%	135.67	29 / 29
muscle	100%	72067.49	803 / 803	0%	0	0 / 0
spleen	100%	120692.40	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	130.69	45 / 45
ureter	0%	0	0 / 0	100%	63.05	1 / 1
blood vessel	100%	68843.68	1333 / 1335	0%	0	0 / 0
heart	98%	46253.92	843 / 861	0%	0	0 / 0
peripheral blood	95%	45669.06	883 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	SRRM2
Protein name	Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803) Serine/arginine repetitive matrix 2 SRRM2 protein
Synonyms	SRM300 KIAA0324 SRL300 HSPC075
Description	FUNCTION: Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). .
Accessions	I3L4U6 I3L4D8 Q05BI2 ENST00000575870.6 I3L0N7 Q9UQ35 ENST00000576924.6 [Q9UQ35-1] ENST00000301740.13 [Q9UQ35-1] ENST00000572883.2 A0A994J493 I3L3Q8 A0A087X1W1 ENST00000574340.1 ENST00000576924.6 ENST00000575009.5 Q05CV9 A0AUK8 ENST00000571378.5 I3L182 ENST00000573692.1 I3L1I8 ENST00000570971.2

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0015030	Cellular component	Cajal body
GO_0016607	Cellular component	nuclear speck
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0005654	Cellular component	nucleoplasm
GO_0071007	Cellular component	U2-type catalytic step 2 spliceosome
GO_0071005	Cellular component	U2-type precatalytic spliceosome
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003729	Molecular function	mRNA binding
GO_0070742	Molecular function	C2H2 zinc finger domain binding
GO_0003723	Molecular function	RNA binding

SRRM2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review