RALY | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	36 studies	31% ± 14%	Explore
natural killer cell	35 studies	36% ± 15%	Explore
T cell	29 studies	32% ± 14%	Explore
CD4-positive, alpha-beta T cell	28 studies	32% ± 16%	Explore
CD8-positive, alpha-beta T cell	28 studies	37% ± 17%	Explore
B cell	26 studies	31% ± 11%	Explore
macrophage	26 studies	25% ± 8%	Explore
fibroblast	26 studies	27% ± 12%	Explore
smooth muscle cell	22 studies	28% ± 11%	Explore
pericyte	21 studies	29% ± 13%	Explore
regulatory T cell	21 studies	34% ± 11%	Explore
conventional dendritic cell	20 studies	33% ± 16%	Explore
non-classical monocyte	18 studies	34% ± 15%	Explore
monocyte	18 studies	27% ± 9%	Explore
endothelial cell of lymphatic vessel	17 studies	28% ± 11%	Explore
mature NK T cell	17 studies	32% ± 10%	Explore
memory B cell	17 studies	26% ± 7%	Explore
plasmacytoid dendritic cell	17 studies	33% ± 13%	Explore
dendritic cell	17 studies	32% ± 17%	Explore
classical monocyte	17 studies	27% ± 12%	Explore
epithelial cell	16 studies	38% ± 19%	Explore
plasma cell	15 studies	39% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	38% ± 14%	Explore
naive B cell	15 studies	25% ± 7%	Explore
gamma-delta T cell	15 studies	35% ± 15%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	34% ± 13%	Explore
basal cell	14 studies	31% ± 16%	Explore
capillary endothelial cell	13 studies	26% ± 15%	Explore
endothelial cell of vascular tree	13 studies	25% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	33% ± 15%	Explore
vein endothelial cell	12 studies	29% ± 16%	Explore
myeloid cell	12 studies	28% ± 9%	Explore
type I pneumocyte	11 studies	31% ± 16%	Explore
plasmablast	11 studies	44% ± 22%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	11 studies	25% ± 6%	Explore
myofibroblast cell	11 studies	34% ± 11%	Explore
connective tissue cell	11 studies	37% ± 15%	Explore
endothelial cell of artery	11 studies	27% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	33% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	32% ± 8%	Explore
microglial cell	10 studies	26% ± 10%	Explore
type II pneumocyte	10 studies	32% ± 13%	Explore
oligodendrocyte	10 studies	27% ± 9%	Explore
club cell	9 studies	32% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	28% ± 12%	Explore
ciliated cell	9 studies	32% ± 9%	Explore
secretory cell	8 studies	24% ± 7%	Explore
progenitor cell	8 studies	30% ± 15%	Explore
goblet cell	8 studies	30% ± 16%	Explore
neuron	8 studies	42% ± 19%	Explore
mucosal invariant T cell	8 studies	32% ± 4%	Explore
abnormal cell	8 studies	34% ± 11%	Explore
astrocyte	7 studies	28% ± 8%	Explore
T follicular helper cell	7 studies	30% ± 7%	Explore
hematopoietic precursor cell	6 studies	43% ± 22%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	36% ± 17%	Explore
mononuclear phagocyte	6 studies	27% ± 15%	Explore
mesothelial cell	6 studies	33% ± 18%	Explore
transit amplifying cell	6 studies	28% ± 10%	Explore
oligodendrocyte precursor cell	6 studies	29% ± 7%	Explore
lymphocyte	6 studies	32% ± 15%	Explore
precursor B cell	6 studies	41% ± 11%	Explore
innate lymphoid cell	6 studies	29% ± 10%	Explore
mast cell	6 studies	24% ± 11%	Explore
respiratory goblet cell	5 studies	28% ± 19%	Explore
leukocyte	5 studies	29% ± 10%	Explore
enterocyte	5 studies	22% ± 6%	Explore
IgA plasma cell	5 studies	26% ± 5%	Explore
IgG plasma cell	5 studies	23% ± 5%	Explore
hematopoietic stem cell	5 studies	33% ± 12%	Explore
pro-B cell	5 studies	45% ± 11%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	39% ± 15%	Explore
glutamatergic neuron	5 studies	37% ± 11%	Explore
squamous epithelial cell	4 studies	32% ± 22%	Explore
platelet	4 studies	23% ± 3%	Explore
exhausted T cell	4 studies	48% ± 9%	Explore
megakaryocyte	4 studies	37% ± 15%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	42% ± 17%	Explore
GABAergic neuron	4 studies	31% ± 10%	Explore
alveolar macrophage	4 studies	21% ± 7%	Explore
interneuron	4 studies	28% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	27% ± 7%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	40% ± 19%	Explore
precursor cell	3 studies	43% ± 16%	Explore
neural crest cell	3 studies	37% ± 12%	Explore
glial cell	3 studies	36% ± 19%	Explore
retinal ganglion cell	3 studies	48% ± 21%	Explore
erythroblast	3 studies	37% ± 25%	Explore
immature B cell	3 studies	37% ± 8%	Explore
retinal pigment epithelial cell	3 studies	26% ± 6%	Explore
retinal rod cell	3 studies	22% ± 4%	Explore
serous secreting cell	3 studies	17% ± 1%	Explore
intraepithelial lymphocyte	3 studies	34% ± 19%	Explore
germinal center B cell	3 studies	35% ± 10%	Explore
enteroendocrine cell	3 studies	36% ± 11%	Explore
group 3 innate lymphoid cell	3 studies	41% ± 12%	Explore
brush cell	3 studies	24% ± 6%	Explore
T-helper 1 cell	3 studies	40% ± 12%	Explore
T-helper 17 cell	3 studies	38% ± 20%	Explore
double negative thymocyte	3 studies	42% ± 20%	Explore
progenitor cell of mammary luminal epithelium	3 studies	19% ± 1%	Explore
erythrocyte	3 studies	35% ± 20%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	16 studies	28% ± 12%	Explore
peripheral blood	15 studies	32% ± 10%	Explore
intestine	9 studies	27% ± 13%	Explore
brain	9 studies	30% ± 8%	Explore
kidney	6 studies	26% ± 9%	Explore
lymph node	5 studies	32% ± 9%	Explore
bone marrow	4 studies	28% ± 11%	Explore
eye	4 studies	25% ± 5%	Explore
heart	4 studies	17% ± 2%	Explore
liver	4 studies	40% ± 21%	Explore
adipose	4 studies	20% ± 6%	Explore
uterus	3 studies	30% ± 12%	Explore
breast	3 studies	24% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	7432.07	1445 / 1445	100%	67.80	183 / 183
ovary	100%	7382.46	180 / 180	100%	91.22	430 / 430
skin	100%	7540.85	1809 / 1809	100%	108.31	472 / 472
stomach	100%	6160.00	359 / 359	100%	113.17	286 / 286
thymus	100%	10491.20	653 / 653	100%	110.51	605 / 605
uterus	100%	7622.39	170 / 170	100%	118.08	459 / 459
lung	100%	9227.74	578 / 578	100%	87.71	1154 / 1155
bladder	100%	7761.90	21 / 21	100%	121.17	503 / 504
brain	100%	4196.95	2636 / 2642	100%	64.82	705 / 705
kidney	100%	6955.27	89 / 89	100%	61.66	898 / 901
intestine	100%	8723.53	966 / 966	100%	121.10	525 / 527
prostate	100%	7422.45	245 / 245	100%	74.02	500 / 502
breast	100%	7557.68	459 / 459	99%	78.67	1111 / 1118
pancreas	100%	3495.97	327 / 328	99%	77.50	177 / 178
liver	100%	2903.18	225 / 226	99%	45.86	402 / 406
adrenal gland	100%	4680.29	258 / 258	98%	46.51	226 / 230
adipose	100%	7667.11	1204 / 1204	0%	0	0 / 0
blood vessel	100%	9181.99	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	88.17	80 / 80
lymph node	0%	0	0 / 0	100%	121.70	29 / 29
spleen	100%	8522.30	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	124.76	45 / 45
ureter	0%	0	0 / 0	100%	67.55	1 / 1
muscle	100%	6363.70	802 / 803	0%	0	0 / 0
heart	100%	6213.75	859 / 861	0%	0	0 / 0
peripheral blood	100%	10658.51	925 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	RALY
Protein name	RNA binding protein (Autoantigenic, hnRNP-associated with lethal yellow) long isoform variant (RNA binding protein, autoantigenic (HnRNP-associated with lethal yellow homolog (Mouse))) (cDNA FLJ77422, highly similar to Homo sapiens RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)), transcript variant 1, mRNA) Alternative protein RALY RALY heterogeneous nuclear ribonucleoprotein RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog)
Synonyms	P542 HNRPCL2 hCG_37136
Description	FUNCTION: RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis (By similarity). May be a heterogeneous nuclear ribonucleoprotein (hnRNP) . .
Accessions	ENST00000375114.7 [Q9UKM9-2] ENST00000246194.8 [Q9UKM9-1] L8E7Y8 Q5QPM2 Q5QPM0 Q5QPL9 Q5QPM1 Q53GL6 ENST00000333552.9 ENST00000413297.5 ENST00000442805.1 Q9UKM9 ENST00000448364.5

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0042632	Biological process	cholesterol homeostasis
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003712	Molecular function	transcription coregulator activity
GO_0003723	Molecular function	RNA binding

RALY report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review