FRG1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	19 studies	24% ± 6%	Explore
B cell	11 studies	22% ± 8%	Explore
endothelial cell	11 studies	27% ± 9%	Explore
regulatory T cell	11 studies	19% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	21% ± 5%	Explore
T cell	9 studies	19% ± 4%	Explore
non-classical monocyte	9 studies	28% ± 12%	Explore
CD8-positive, alpha-beta T cell	9 studies	22% ± 7%	Explore
smooth muscle cell	8 studies	20% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	24% ± 4%	Explore
pericyte	8 studies	21% ± 5%	Explore
gamma-delta T cell	7 studies	27% ± 15%	Explore
monocyte	6 studies	20% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	20% ± 4%	Explore
CD4-positive, alpha-beta T cell	6 studies	25% ± 6%	Explore
conventional dendritic cell	6 studies	29% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	21% ± 5%	Explore
mature NK T cell	6 studies	19% ± 2%	Explore
macrophage	6 studies	28% ± 7%	Explore
fibroblast	6 studies	30% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	22% ± 5%	Explore
classical monocyte	5 studies	28% ± 10%	Explore
naive B cell	5 studies	20% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	22% ± 6%	Explore
capillary endothelial cell	5 studies	20% ± 5%	Explore
connective tissue cell	5 studies	23% ± 6%	Explore
endothelial cell of lymphatic vessel	4 studies	22% ± 6%	Explore
hematopoietic precursor cell	4 studies	26% ± 11%	Explore
epithelial cell	4 studies	46% ± 13%	Explore
pro-B cell	4 studies	24% ± 4%	Explore
ciliated cell	4 studies	30% ± 6%	Explore
T follicular helper cell	4 studies	16% ± 0%	Explore
innate lymphoid cell	4 studies	19% ± 2%	Explore
mast cell	4 studies	18% ± 3%	Explore
plasmacytoid dendritic cell	4 studies	25% ± 8%	Explore
memory B cell	4 studies	19% ± 1%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	23% ± 3%	Explore
leukocyte	3 studies	27% ± 3%	Explore
mononuclear phagocyte	3 studies	24% ± 11%	Explore
myofibroblast cell	3 studies	24% ± 6%	Explore
precursor B cell	3 studies	29% ± 12%	Explore
erythroblast	3 studies	33% ± 23%	Explore
goblet cell	3 studies	22% ± 8%	Explore
double negative thymocyte	3 studies	34% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	21% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	24% ± 8%	Explore
lung	6 studies	26% ± 6%	Explore
brain	4 studies	19% ± 2%	Explore
eye	3 studies	20% ± 5%	Explore
intestine	3 studies	24% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1147.13	1445 / 1445	100%	33.49	183 / 183
ovary	100%	1199.17	180 / 180	100%	37.07	430 / 430
prostate	100%	909.80	245 / 245	100%	39.35	502 / 502
lung	100%	988.97	578 / 578	100%	38.78	1154 / 1155
breast	100%	1414.49	459 / 459	100%	55.11	1117 / 1118
thymus	100%	962.10	653 / 653	100%	58.93	604 / 605
brain	100%	830.71	2635 / 2642	100%	51.68	704 / 705
adrenal gland	100%	952.61	258 / 258	100%	44.03	229 / 230
uterus	100%	1271.02	170 / 170	100%	61.38	457 / 459
kidney	100%	891.99	89 / 89	100%	33.14	897 / 901
pancreas	99%	659.66	326 / 328	100%	40.49	178 / 178
skin	100%	1204.92	1809 / 1809	99%	47.77	469 / 472
stomach	100%	928.81	359 / 359	99%	34.87	284 / 286
liver	99%	529.16	224 / 226	100%	29.57	405 / 406
bladder	100%	1119.33	21 / 21	98%	42.00	496 / 504
intestine	100%	1181.18	966 / 966	98%	36.66	518 / 527
adipose	100%	1370.37	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1361.27	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	81.63	29 / 29
spleen	100%	1144.60	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	60.87	45 / 45
ureter	0%	0	0 / 0	100%	20.60	1 / 1
muscle	100%	699.53	799 / 803	0%	0	0 / 0
heart	99%	754.38	852 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	28.65	78 / 80
peripheral blood	97%	974.85	903 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0006364	Biological process	rRNA processing
GO_0007517	Biological process	muscle organ development
GO_0015030	Cellular component	Cajal body
GO_0005730	Cellular component	nucleolus
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0055120	Cellular component	striated muscle dense body
GO_0030018	Cellular component	Z disc
GO_0051015	Molecular function	actin filament binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	FRG1
Protein name	Protein FRG1 (FSHD region gene 1 protein) FSHD region gene 1 (Protein FRG1)
Synonyms
Description	FUNCTION: Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B. .
Accessions	E9PI42 ENST00000636590.2 ENST00000637998.2 J3KSQ7 ENST00000627980.1 ENST00000636972.1 ENST00000636883.1 ENST00000531991.6 ENST00000636021.1 ENST00000624356.3 ENST00000533157.5 ENST00000507103.1 ENST00000627466.2 E9PRR7 ENST00000226798.9 ENST00000620886.3 ENST00000524583.5 E9PLY7 ENST00000625559.2 Q14331 ENST00000636553.1

FRG1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review