SRSF7 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	46 studies	53% ± 17%	Explore
endothelial cell	43 studies	43% ± 17%	Explore
natural killer cell	42 studies	54% ± 16%	Explore
fibroblast	41 studies	43% ± 17%	Explore
T cell	39 studies	54% ± 18%	Explore
CD8-positive, alpha-beta T cell	39 studies	60% ± 18%	Explore
macrophage	34 studies	39% ± 13%	Explore
CD4-positive, alpha-beta T cell	34 studies	59% ± 18%	Explore
pericyte	32 studies	45% ± 18%	Explore
smooth muscle cell	29 studies	42% ± 15%	Explore
conventional dendritic cell	29 studies	53% ± 14%	Explore
dendritic cell	28 studies	42% ± 22%	Explore
regulatory T cell	26 studies	62% ± 15%	Explore
mast cell	24 studies	42% ± 19%	Explore
endothelial cell of lymphatic vessel	23 studies	41% ± 14%	Explore
mature NK T cell	22 studies	53% ± 18%	Explore
non-classical monocyte	22 studies	40% ± 15%	Explore
plasmacytoid dendritic cell	22 studies	61% ± 18%	Explore
basal cell	22 studies	45% ± 17%	Explore
classical monocyte	22 studies	33% ± 12%	Explore
monocyte	21 studies	35% ± 13%	Explore
epithelial cell	21 studies	46% ± 20%	Explore
memory B cell	20 studies	60% ± 13%	Explore
naive B cell	20 studies	51% ± 12%	Explore
gamma-delta T cell	19 studies	60% ± 19%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	19 studies	47% ± 15%	Explore
ciliated cell	18 studies	37% ± 15%	Explore
plasma cell	17 studies	42% ± 14%	Explore
mucosal invariant T cell	17 studies	61% ± 17%	Explore
connective tissue cell	17 studies	48% ± 15%	Explore
myeloid cell	17 studies	38% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	53% ± 18%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	53% ± 17%	Explore
myofibroblast cell	15 studies	47% ± 17%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	53% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	59% ± 20%	Explore
capillary endothelial cell	13 studies	41% ± 12%	Explore
microglial cell	13 studies	35% ± 17%	Explore
endothelial cell of vascular tree	13 studies	49% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	63% ± 13%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	68% ± 17%	Explore
secretory cell	12 studies	39% ± 14%	Explore
vein endothelial cell	12 studies	43% ± 9%	Explore
type II pneumocyte	11 studies	39% ± 17%	Explore
type I pneumocyte	10 studies	41% ± 18%	Explore
plasmablast	10 studies	56% ± 22%	Explore
leukocyte	10 studies	52% ± 17%	Explore
abnormal cell	10 studies	47% ± 16%	Explore
endothelial cell of artery	10 studies	42% ± 9%	Explore
astrocyte	10 studies	34% ± 12%	Explore
progenitor cell	9 studies	53% ± 17%	Explore
goblet cell	9 studies	32% ± 13%	Explore
mesothelial cell	9 studies	51% ± 20%	Explore
T follicular helper cell	9 studies	59% ± 24%	Explore
oligodendrocyte precursor cell	9 studies	37% ± 14%	Explore
innate lymphoid cell	8 studies	52% ± 18%	Explore
neuron	8 studies	47% ± 19%	Explore
glutamatergic neuron	8 studies	36% ± 22%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	68% ± 9%	Explore
mononuclear phagocyte	7 studies	41% ± 22%	Explore
erythrocyte	7 studies	43% ± 22%	Explore
enterocyte	7 studies	26% ± 8%	Explore
transit amplifying cell	7 studies	35% ± 17%	Explore
precursor B cell	7 studies	57% ± 13%	Explore
club cell	7 studies	40% ± 17%	Explore
adipocyte	7 studies	30% ± 12%	Explore
GABAergic neuron	7 studies	34% ± 16%	Explore
oligodendrocyte	7 studies	31% ± 10%	Explore
alveolar macrophage	6 studies	27% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	47% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	63% ± 8%	Explore
kidney loop of Henle epithelial cell	6 studies	25% ± 8%	Explore
IgA plasma cell	6 studies	25% ± 3%	Explore
IgG plasma cell	6 studies	23% ± 8%	Explore
retinal rod cell	6 studies	31% ± 9%	Explore
lymphocyte	6 studies	45% ± 22%	Explore
immature B cell	6 studies	60% ± 8%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	70% ± 17%	Explore
interneuron	6 studies	31% ± 16%	Explore
CD4-positive helper T cell	5 studies	65% ± 20%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	53% ± 6%	Explore
hematopoietic precursor cell	5 studies	61% ± 21%	Explore
exhausted T cell	5 studies	60% ± 10%	Explore
amacrine cell	5 studies	35% ± 16%	Explore
hematopoietic stem cell	5 studies	49% ± 9%	Explore
pro-B cell	5 studies	57% ± 13%	Explore
T-helper 17 cell	5 studies	72% ± 17%	Explore
group 3 innate lymphoid cell	5 studies	71% ± 14%	Explore
retinal pigment epithelial cell	5 studies	38% ± 13%	Explore
glial cell	5 studies	37% ± 24%	Explore
Mueller cell	5 studies	41% ± 10%	Explore
granulocyte	5 studies	47% ± 8%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	45% ± 18%	Explore
deuterosomal cell	4 studies	36% ± 0%	Explore
platelet	4 studies	23% ± 4%	Explore
glomerular endothelial cell	4 studies	44% ± 15%	Explore
enteroendocrine cell	4 studies	48% ± 11%	Explore
intestinal crypt stem cell	4 studies	34% ± 7%	Explore
retinal bipolar neuron	4 studies	37% ± 15%	Explore
erythroblast	4 studies	63% ± 16%	Explore
brush cell	4 studies	37% ± 14%	Explore
retina horizontal cell	4 studies	32% ± 12%	Explore
adventitial cell	4 studies	38% ± 14%	Explore
muscle cell	4 studies	43% ± 13%	Explore
germinal center B cell	4 studies	48% ± 15%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	45% ± 6%	Explore
hepatocyte	4 studies	38% ± 23%	Explore
megakaryocyte-erythroid progenitor cell	4 studies	58% ± 24%	Explore
keratinocyte	4 studies	34% ± 9%	Explore
T-helper 1 cell	4 studies	73% ± 17%	Explore
double negative thymocyte	4 studies	61% ± 21%	Explore
duct epithelial cell	3 studies	18% ± 2%	Explore
ionocyte	3 studies	35% ± 11%	Explore
precursor cell	3 studies	62% ± 21%	Explore
pancreatic A cell	3 studies	53% ± 4%	Explore
type B pancreatic cell	3 studies	45% ± 3%	Explore
monocyte-derived dendritic cell	3 studies	50% ± 21%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	51% ± 20%	Explore
renal alpha-intercalated cell	3 studies	47% ± 14%	Explore
neural crest cell	3 studies	67% ± 18%	Explore
retinal ganglion cell	3 studies	32% ± 15%	Explore
renal principal cell	3 studies	34% ± 13%	Explore
extravillous trophoblast	3 studies	49% ± 22%	Explore
placental villous trophoblast	3 studies	53% ± 17%	Explore
neuroendocrine cell	3 studies	31% ± 12%	Explore
Schwann cell	3 studies	57% ± 26%	Explore
retinal cone cell	3 studies	46% ± 13%	Explore
tissue-resident macrophage	3 studies	47% ± 19%	Explore
intraepithelial lymphocyte	3 studies	52% ± 13%	Explore
respiratory goblet cell	3 studies	39% ± 22%	Explore
intermediate monocyte	3 studies	55% ± 21%	Explore
myoepithelial cell	3 studies	52% ± 16%	Explore
pancreatic ductal cell	3 studies	51% ± 17%	Explore
melanocyte	3 studies	34% ± 14%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	57% ± 12%	Explore
double-positive, alpha-beta thymocyte	3 studies	71% ± 16%	Explore
progenitor cell of mammary luminal epithelium	3 studies	52% ± 17%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	19 studies	42% ± 15%	Explore
peripheral blood	19 studies	47% ± 15%	Explore
brain	14 studies	33% ± 15%	Explore
intestine	12 studies	42% ± 19%	Explore
eye	10 studies	36% ± 15%	Explore
kidney	9 studies	38% ± 15%	Explore
liver	7 studies	45% ± 23%	Explore
lymph node	6 studies	54% ± 22%	Explore
bone marrow	5 studies	39% ± 13%	Explore
uterus	5 studies	55% ± 16%	Explore
pancreas	4 studies	45% ± 13%	Explore
placenta	4 studies	38% ± 20%	Explore
heart	4 studies	22% ± 5%	Explore
adipose	4 studies	35% ± 12%	Explore
esophagus	4 studies	40% ± 26%	Explore
prostate	4 studies	45% ± 7%	Explore
breast	4 studies	55% ± 8%	Explore
adrenal gland	3 studies	49% ± 19%	Explore
skin	3 studies	31% ± 6%	Explore
thymus	3 studies	63% ± 22%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	7460.43	21 / 21	100%	109.80	504 / 504
breast	100%	8894.91	459 / 459	100%	106.48	1118 / 1118
esophagus	100%	7414.93	1445 / 1445	100%	85.49	183 / 183
ovary	100%	9581.52	180 / 180	100%	97.10	430 / 430
prostate	100%	8873.97	245 / 245	100%	97.45	502 / 502
stomach	100%	7023.85	359 / 359	100%	94.35	286 / 286
uterus	100%	9811.36	170 / 170	100%	135.43	459 / 459
lung	100%	7897.47	577 / 578	100%	100.49	1155 / 1155
intestine	100%	9401.66	966 / 966	100%	105.44	526 / 527
thymus	100%	9477.66	653 / 653	100%	90.29	603 / 605
pancreas	100%	4500.62	328 / 328	99%	81.15	177 / 178
skin	100%	6448.31	1809 / 1809	99%	89.11	467 / 472
brain	99%	4615.87	2614 / 2642	100%	79.94	705 / 705
liver	100%	5343.06	226 / 226	99%	45.54	401 / 406
adrenal gland	100%	7048.92	258 / 258	98%	61.57	226 / 230
kidney	100%	6496.04	89 / 89	97%	54.72	875 / 901
adipose	100%	9125.56	1204 / 1204	0%	0	0 / 0
blood vessel	100%	6026.01	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	146.99	29 / 29
spleen	100%	12000.10	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	112.60	45 / 45
ureter	0%	0	0 / 0	100%	45.56	1 / 1
heart	99%	3562.26	851 / 861	0%	0	0 / 0
muscle	97%	2769.36	780 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	95%	64.02	76 / 80
peripheral blood	85%	4854.75	787 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_1990830	Biological process	cellular response to leukemia inhibitory factor
GO_0048025	Biological process	negative regulation of mRNA splicing, via spliceosome
GO_0008380	Biological process	RNA splicing
GO_0006397	Biological process	mRNA processing
GO_0051028	Biological process	mRNA transport
GO_0016607	Cellular component	nuclear speck
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0019904	Molecular function	protein domain specific binding
GO_0005515	Molecular function	protein binding
GO_0003729	Molecular function	mRNA binding
GO_0008270	Molecular function	zinc ion binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	SRSF7
Protein name	Serine and arginine rich splicing factor 7 (Splicing factor, arginine/serine-rich 7, 35kDa, isoform CRA_a) Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7) Serine and arginine rich splicing factor 7
Synonyms	hCG_15878 SFRS7
Description	FUNCTION: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific. .
Accessions	F8WEA1 C9JAB2 ENST00000425941.6 H7C1N1 H7BZZ6 ENST00000443213.5 [Q16629-3] A0A0B4J1Z1 ENST00000425778.5 ENST00000415527.1 ENST00000409276.5 ENST00000431066.5 [Q16629-3] ENST00000313117.11 [Q16629-1] ENST00000452806.5 Q16629 ENST00000446327.6 [Q16629-4] ENST00000432873.5

SRSF7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review