Name | Number of supported studies | Average coverage | |
---|---|---|---|
type I pneumocyte | 8 studies | 31% ± 13% | |
endothelial cell | 5 studies | 26% ± 9% | |
oligodendrocyte | 5 studies | 24% ± 7% | |
epithelial cell | 4 studies | 35% ± 7% | |
glutamatergic neuron | 4 studies | 25% ± 16% | |
macrophage | 4 studies | 24% ± 7% | |
astrocyte | 4 studies | 28% ± 14% | |
fibroblast | 3 studies | 22% ± 8% | |
adipocyte | 3 studies | 22% ± 3% | |
GABAergic neuron | 3 studies | 30% ± 13% | |
interneuron | 3 studies | 49% ± 24% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 33% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 100% | 1332.66 | 170 / 170 | 100% | 10.37 | 459 / 459 |
thymus | 100% | 1651.86 | 653 / 653 | 100% | 12.04 | 604 / 605 |
brain | 100% | 1138.34 | 2634 / 2642 | 100% | 13.80 | 705 / 705 |
lung | 100% | 1535.60 | 578 / 578 | 100% | 12.36 | 1150 / 1155 |
adrenal gland | 100% | 1160.80 | 258 / 258 | 100% | 9.60 | 229 / 230 |
esophagus | 100% | 1090.98 | 1445 / 1445 | 99% | 9.67 | 182 / 183 |
pancreas | 100% | 607.08 | 328 / 328 | 99% | 11.51 | 177 / 178 |
bladder | 100% | 1254.29 | 21 / 21 | 99% | 11.18 | 500 / 504 |
ovary | 100% | 1113.27 | 180 / 180 | 99% | 9.39 | 425 / 430 |
prostate | 100% | 1624.88 | 245 / 245 | 99% | 7.93 | 496 / 502 |
intestine | 100% | 1169.10 | 966 / 966 | 99% | 8.09 | 520 / 527 |
breast | 100% | 1138.75 | 459 / 459 | 98% | 7.56 | 1100 / 1118 |
stomach | 100% | 771.34 | 359 / 359 | 97% | 7.92 | 277 / 286 |
kidney | 100% | 1229.81 | 89 / 89 | 95% | 10.38 | 856 / 901 |
liver | 100% | 820.81 | 226 / 226 | 94% | 6.44 | 383 / 406 |
skin | 100% | 1009.89 | 1806 / 1809 | 88% | 5.72 | 416 / 472 |
adipose | 100% | 1059.00 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 13.13 | 29 / 29 |
spleen | 100% | 1998.96 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 32.24 | 1 / 1 |
blood vessel | 100% | 1069.02 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 637.38 | 856 / 861 | 0% | 0 | 0 / 0 |
muscle | 99% | 570.62 | 794 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 5.34 | 43 / 45 |
peripheral blood | 95% | 573.51 | 886 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 68% | 4.28 | 54 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000398 | Biological process | mRNA splicing, via spliceosome |
GO_0010826 | Biological process | negative regulation of centrosome duplication |
GO_0042176 | Biological process | regulation of protein catabolic process |
GO_0051304 | Biological process | chromosome separation |
GO_0005813 | Cellular component | centrosome |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
Gene name | CENATAC |
Protein name | Centrosomal AT-AC splicing factor (Coiled-coil domain-containing protein 84) |
Synonyms | CCDC84 DLNB14 |
Description | FUNCTION: Component of the minor spliceosome that promotes splicing of a specific, rare minor intron subtype . Negative regulator of centrosome duplication . Constrains centriole number by modulating the degradation of the centrosome-duplication-associated protein SASS6 in an acetylation-dependent manner. SIRT1 deacetylates CENATAC in G1 phase, allowing for SASS6 accumulation on the centrosome and subsequent procentriole assembly. The CENATAC acetylation level is restored in mitosis by NAT10, promoting SASS6 proteasome degradation by facilitating SASS6 binding to APC/C E3 ubiquitin-protein ligase complex/FZR1 . . |
Accessions | ENST00000626123 ENST00000625528.3 ENST00000532132.5 ENST00000334418.6 Q86UT8 E9PPT8 E9PJ16 ENST00000526463.5 ENST00000626384 |