SNRPN | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
CD4-positive, alpha-beta T cell	19 studies	28% ± 8%	Explore
endothelial cell	18 studies	29% ± 14%	Explore
CD8-positive, alpha-beta T cell	17 studies	28% ± 9%	Explore
natural killer cell	16 studies	24% ± 6%	Explore
fibroblast	16 studies	32% ± 16%	Explore
regulatory T cell	16 studies	26% ± 6%	Explore
B cell	15 studies	24% ± 6%	Explore
smooth muscle cell	14 studies	32% ± 12%	Explore
T cell	13 studies	29% ± 16%	Explore
gamma-delta T cell	13 studies	28% ± 14%	Explore
plasmacytoid dendritic cell	12 studies	38% ± 11%	Explore
mast cell	11 studies	24% ± 7%	Explore
naive B cell	11 studies	21% ± 4%	Explore
glutamatergic neuron	11 studies	48% ± 24%	Explore
pericyte	11 studies	27% ± 7%	Explore
astrocyte	11 studies	35% ± 18%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	29% ± 9%	Explore
GABAergic neuron	10 studies	54% ± 27%	Explore
memory B cell	10 studies	23% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	22% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	25% ± 7%	Explore
mature NK T cell	9 studies	24% ± 4%	Explore
connective tissue cell	9 studies	28% ± 14%	Explore
neuron	9 studies	43% ± 16%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	23% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	27% ± 5%	Explore
T follicular helper cell	8 studies	31% ± 8%	Explore
retinal ganglion cell	8 studies	74% ± 32%	Explore
mucosal invariant T cell	8 studies	24% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	30% ± 10%	Explore
myofibroblast cell	7 studies	41% ± 15%	Explore
amacrine cell	7 studies	54% ± 22%	Explore
interneuron	7 studies	52% ± 34%	Explore
retinal cone cell	7 studies	47% ± 27%	Explore
ciliated cell	7 studies	36% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	26% ± 6%	Explore
endothelial cell of lymphatic vessel	6 studies	25% ± 8%	Explore
platelet	6 studies	29% ± 5%	Explore
epithelial cell of proximal tubule	6 studies	28% ± 6%	Explore
kidney loop of Henle epithelial cell	6 studies	40% ± 10%	Explore
renal alpha-intercalated cell	6 studies	40% ± 7%	Explore
epithelial cell	6 studies	30% ± 13%	Explore
oligodendrocyte precursor cell	6 studies	31% ± 21%	Explore
retinal rod cell	6 studies	31% ± 13%	Explore
retina horizontal cell	6 studies	62% ± 23%	Explore
cardiac muscle cell	6 studies	30% ± 7%	Explore
capillary endothelial cell	5 studies	17% ± 1%	Explore
progenitor cell	5 studies	22% ± 10%	Explore
microglial cell	5 studies	26% ± 9%	Explore
plasma cell	5 studies	32% ± 13%	Explore
oligodendrocyte	5 studies	34% ± 15%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	20% ± 2%	Explore
conventional dendritic cell	4 studies	24% ± 5%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	51% ± 2%	Explore
enteroendocrine cell	4 studies	25% ± 8%	Explore
retinal bipolar neuron	4 studies	54% ± 21%	Explore
OFF-bipolar cell	4 studies	51% ± 30%	Explore
ON-bipolar cell	4 studies	55% ± 28%	Explore
GABAergic amacrine cell	4 studies	52% ± 21%	Explore
precursor B cell	4 studies	29% ± 7%	Explore
Mueller cell	4 studies	35% ± 13%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	30% ± 14%	Explore
innate lymphoid cell	4 studies	23% ± 3%	Explore
basal cell	4 studies	24% ± 11%	Explore
secretory cell	4 studies	24% ± 8%	Explore
hematopoietic precursor cell	3 studies	32% ± 12%	Explore
leukocyte	3 studies	19% ± 2%	Explore
glomerular endothelial cell	3 studies	18% ± 3%	Explore
endothelial cell of artery	3 studies	22% ± 5%	Explore
mesothelial cell	3 studies	30% ± 7%	Explore
neural crest cell	3 studies	29% ± 3%	Explore
GABAergic interneuron	3 studies	52% ± 18%	Explore
glycinergic amacrine cell	3 studies	46% ± 13%	Explore
abnormal cell	3 studies	25% ± 6%	Explore
endothelial cell of vascular tree	3 studies	20% ± 4%	Explore
pro-B cell	3 studies	24% ± 2%	Explore
retinal pigment epithelial cell	3 studies	35% ± 24%	Explore
rod bipolar cell	3 studies	53% ± 16%	Explore
CD4-positive helper T cell	3 studies	21% ± 6%	Explore
myoepithelial cell	3 studies	26% ± 8%	Explore
luminal cell of prostate epithelium	3 studies	41% ± 4%	Explore
macrophage	3 studies	29% ± 6%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	33% ± 21%	Explore
T-helper 17 cell	3 studies	24% ± 2%	Explore
granule cell	3 studies	29% ± 5%	Explore
hematopoietic stem cell	3 studies	22% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	23% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	14 studies	32% ± 21%	Explore
peripheral blood	8 studies	26% ± 7%	Explore
eye	8 studies	39% ± 16%	Explore
kidney	7 studies	27% ± 6%	Explore
intestine	4 studies	21% ± 4%	Explore
lung	4 studies	33% ± 11%	Explore
uterus	4 studies	24% ± 7%	Explore
thymus	3 studies	36% ± 14%	Explore
lymph node	3 studies	24% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	6740.95	653 / 653	99%	7.83	599 / 605
brain	100%	10781.43	2642 / 2642	99%	7.57	695 / 705
prostate	100%	4361.28	244 / 245	99%	9.29	495 / 502
adrenal gland	100%	3680.12	258 / 258	83%	12.04	192 / 230
kidney	100%	3836.43	89 / 89	81%	3.06	727 / 901
ovary	100%	3133.71	180 / 180	78%	4.15	337 / 430
bladder	90%	1902.24	19 / 21	47%	1.98	237 / 504
lung	95%	1767.61	550 / 578	38%	1.34	434 / 1155
pancreas	71%	968.20	234 / 328	60%	2.52	106 / 178
breast	72%	1125.13	330 / 459	55%	1.89	616 / 1118
uterus	97%	1932.34	165 / 170	30%	1.33	137 / 459
stomach	89%	1510.41	319 / 359	25%	0.95	72 / 286
intestine	78%	1490.16	750 / 966	25%	0.94	133 / 527
spleen	100%	1973.52	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	5.10	1 / 1
blood vessel	98%	2938.31	1303 / 1335	0%	0	0 / 0
muscle	98%	2744.44	783 / 803	0%	0	0 / 0
heart	97%	5421.60	836 / 861	0%	0	0 / 0
esophagus	65%	1170.29	933 / 1445	20%	0.71	36 / 183
eye	0%	0	0 / 0	79%	2.56	63 / 80
skin	27%	333.38	497 / 1809	44%	1.42	207 / 472
lymph node	0%	0	0 / 0	69%	2.96	20 / 29
liver	23%	289.69	53 / 226	38%	2.05	154 / 406
adipose	50%	677.36	599 / 1204	0%	0	0 / 0
peripheral blood	35%	516.78	326 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	11%	0.25	5 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0008380	Biological process	RNA splicing
GO_0005686	Cellular component	U2 snRNP
GO_0005687	Cellular component	U4 snRNP
GO_0046540	Cellular component	U4/U6 x U5 tri-snRNP complex
GO_0071004	Cellular component	U2-type prespliceosome
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0005654	Cellular component	nucleoplasm
GO_0005685	Cellular component	U1 snRNP
GO_0030532	Cellular component	small nuclear ribonucleoprotein complex
GO_0005681	Cellular component	spliceosomal complex
GO_0005737	Cellular component	cytoplasm
GO_0005682	Cellular component	U5 snRNP
GO_0070990	Molecular function	snRNP binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	SNRPN
Protein name	Small nuclear ribonucleoprotein polypeptide N Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein D) (Sm-D) (Sm protein N) (Sm-N) (SmN) (Tissue-specific-splicing protein) HCG15924, isoform CRA_a (Small nuclear ribonucleoprotein polypeptide N isoform A)
Synonyms	SMN hCG_15924 HCERN3
Description	FUNCTION: May be involved in tissue-specific alternative RNA processing events.
Accessions	ENST00000584968.5 ENST00000577565.1 [P63162-1] ENST00000554227.6 [P63162-2] ENST00000400100.5 [P63162-1] ENST00000400097.5 [P63162-1] ENST00000642807.1 [P63162-1] ENST00000645002.1 [P63162-1] P63162 J3KRY3 J3QLE5 ENST00000390687.9 [P63162-1] X5DP00 ENST00000579070.5 ENST00000346403.10 [P63162-1]

SNRPN report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review