SRSF5 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	47 studies	55% ± 20%	Explore
endothelial cell	46 studies	48% ± 19%	Explore
fibroblast	45 studies	48% ± 17%	Explore
natural killer cell	43 studies	59% ± 19%	Explore
T cell	38 studies	49% ± 18%	Explore
CD8-positive, alpha-beta T cell	38 studies	53% ± 17%	Explore
macrophage	37 studies	41% ± 15%	Explore
CD4-positive, alpha-beta T cell	35 studies	56% ± 19%	Explore
pericyte	33 studies	51% ± 17%	Explore
smooth muscle cell	32 studies	47% ± 16%	Explore
mast cell	28 studies	48% ± 23%	Explore
conventional dendritic cell	28 studies	59% ± 20%	Explore
dendritic cell	26 studies	51% ± 22%	Explore
classical monocyte	26 studies	60% ± 15%	Explore
regulatory T cell	26 studies	65% ± 15%	Explore
endothelial cell of lymphatic vessel	25 studies	46% ± 14%	Explore
non-classical monocyte	25 studies	66% ± 19%	Explore
plasmacytoid dendritic cell	24 studies	63% ± 16%	Explore
monocyte	23 studies	48% ± 18%	Explore
basal cell	23 studies	55% ± 18%	Explore
epithelial cell	23 studies	53% ± 22%	Explore
mature NK T cell	21 studies	56% ± 17%	Explore
astrocyte	21 studies	42% ± 20%	Explore
ciliated cell	20 studies	58% ± 20%	Explore
gamma-delta T cell	20 studies	62% ± 19%	Explore
memory B cell	20 studies	70% ± 13%	Explore
naive B cell	20 studies	64% ± 13%	Explore
plasma cell	19 studies	43% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	19 studies	65% ± 20%	Explore
connective tissue cell	19 studies	46% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	17 studies	67% ± 22%	Explore
mucosal invariant T cell	17 studies	63% ± 21%	Explore
CD16-positive, CD56-dim natural killer cell, human	16 studies	66% ± 19%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	71% ± 13%	Explore
capillary endothelial cell	15 studies	43% ± 15%	Explore
myofibroblast cell	15 studies	50% ± 12%	Explore
oligodendrocyte	14 studies	38% ± 14%	Explore
microglial cell	14 studies	33% ± 15%	Explore
endothelial cell of vascular tree	14 studies	54% ± 16%	Explore
myeloid cell	14 studies	48% ± 23%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	63% ± 22%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	64% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	64% ± 19%	Explore
vein endothelial cell	13 studies	47% ± 11%	Explore
type I pneumocyte	12 studies	43% ± 19%	Explore
type II pneumocyte	12 studies	45% ± 18%	Explore
secretory cell	12 studies	57% ± 13%	Explore
oligodendrocyte precursor cell	12 studies	37% ± 16%	Explore
club cell	11 studies	41% ± 20%	Explore
endothelial cell of artery	11 studies	49% ± 13%	Explore
goblet cell	11 studies	47% ± 21%	Explore
innate lymphoid cell	10 studies	62% ± 22%	Explore
plasmablast	10 studies	56% ± 20%	Explore
leukocyte	10 studies	49% ± 17%	Explore
progenitor cell	10 studies	47% ± 18%	Explore
abnormal cell	10 studies	50% ± 17%	Explore
mesothelial cell	10 studies	49% ± 19%	Explore
GABAergic neuron	9 studies	45% ± 21%	Explore
glutamatergic neuron	9 studies	48% ± 25%	Explore
neutrophil	9 studies	33% ± 15%	Explore
T follicular helper cell	9 studies	68% ± 19%	Explore
adipocyte	9 studies	43% ± 14%	Explore
alveolar macrophage	8 studies	38% ± 14%	Explore
renal alpha-intercalated cell	8 studies	52% ± 21%	Explore
neuron	8 studies	43% ± 20%	Explore
retinal rod cell	8 studies	42% ± 19%	Explore
hematopoietic stem cell	8 studies	78% ± 22%	Explore
respiratory goblet cell	7 studies	34% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	60% ± 6%	Explore
mononuclear phagocyte	7 studies	47% ± 27%	Explore
kidney loop of Henle epithelial cell	7 studies	37% ± 14%	Explore
IgG plasma cell	7 studies	30% ± 8%	Explore
amacrine cell	7 studies	54% ± 20%	Explore
retinal ganglion cell	7 studies	51% ± 27%	Explore
retinal cone cell	7 studies	46% ± 27%	Explore
precursor B cell	7 studies	63% ± 18%	Explore
immature B cell	7 studies	69% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	55% ± 15%	Explore
ionocyte	6 studies	49% ± 14%	Explore
platelet	6 studies	38% ± 22%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	66% ± 7%	Explore
epithelial cell of proximal tubule	6 studies	28% ± 10%	Explore
kidney distal convoluted tubule epithelial cell	6 studies	47% ± 12%	Explore
enterocyte	6 studies	40% ± 13%	Explore
IgA plasma cell	6 studies	29% ± 7%	Explore
transit amplifying cell	6 studies	36% ± 22%	Explore
retina horizontal cell	6 studies	66% ± 10%	Explore
glial cell	6 studies	42% ± 22%	Explore
lymphocyte	6 studies	45% ± 20%	Explore
mucus secreting cell	6 studies	25% ± 6%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	74% ± 14%	Explore
hepatocyte	6 studies	42% ± 23%	Explore
CD4-positive helper T cell	5 studies	58% ± 20%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	75% ± 11%	Explore
hematopoietic precursor cell	5 studies	79% ± 22%	Explore
duct epithelial cell	5 studies	41% ± 9%	Explore
exhausted T cell	5 studies	61% ± 17%	Explore
enteroendocrine cell	5 studies	47% ± 22%	Explore
erythroblast	5 studies	51% ± 31%	Explore
pro-B cell	5 studies	66% ± 17%	Explore
brush cell	5 studies	36% ± 19%	Explore
T-helper 17 cell	5 studies	61% ± 16%	Explore
group 3 innate lymphoid cell	5 studies	75% ± 12%	Explore
retinal pigment epithelial cell	5 studies	64% ± 20%	Explore
adventitial cell	5 studies	43% ± 19%	Explore
cardiac muscle cell	5 studies	36% ± 8%	Explore
Mueller cell	5 studies	61% ± 17%	Explore
double negative thymocyte	5 studies	79% ± 10%	Explore
intermediate monocyte	5 studies	64% ± 19%	Explore
granulocyte	5 studies	62% ± 18%	Explore
interneuron	5 studies	54% ± 20%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	52% ± 21%	Explore
deuterosomal cell	4 studies	40% ± 3%	Explore
squamous epithelial cell	4 studies	53% ± 21%	Explore
pancreatic A cell	4 studies	66% ± 7%	Explore
type B pancreatic cell	4 studies	54% ± 14%	Explore
glomerular endothelial cell	4 studies	60% ± 13%	Explore
podocyte	4 studies	53% ± 20%	Explore
intestinal crypt stem cell	4 studies	36% ± 8%	Explore
retinal bipolar neuron	4 studies	69% ± 21%	Explore
OFF-bipolar cell	4 studies	44% ± 6%	Explore
ON-bipolar cell	4 studies	49% ± 9%	Explore
renal principal cell	4 studies	50% ± 19%	Explore
chondrocyte	4 studies	42% ± 23%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	70% ± 3%	Explore
luminal cell of prostate epithelium	4 studies	53% ± 12%	Explore
muscle cell	4 studies	49% ± 21%	Explore
erythrocyte	4 studies	52% ± 12%	Explore
keratinocyte	4 studies	38% ± 12%	Explore
T-helper 1 cell	4 studies	72% ± 15%	Explore
pancreatic D cell	3 studies	61% ± 11%	Explore
monocyte-derived dendritic cell	3 studies	67% ± 26%	Explore
kidney connecting tubule epithelial cell	3 studies	50% ± 26%	Explore
parietal epithelial cell	3 studies	46% ± 21%	Explore
interstitial cell of Cajal	3 studies	54% ± 8%	Explore
neural crest cell	3 studies	47% ± 11%	Explore
GABAergic amacrine cell	3 studies	41% ± 13%	Explore
glycinergic amacrine cell	3 studies	42% ± 10%	Explore
thymocyte	3 studies	59% ± 25%	Explore
extravillous trophoblast	3 studies	44% ± 15%	Explore
placental villous trophoblast	3 studies	71% ± 8%	Explore
neuroendocrine cell	3 studies	59% ± 26%	Explore
tissue-resident macrophage	3 studies	50% ± 19%	Explore
intraepithelial lymphocyte	3 studies	47% ± 19%	Explore
rod bipolar cell	3 studies	60% ± 11%	Explore
acinar cell	3 studies	27% ± 14%	Explore
endothelial cell of sinusoid	3 studies	27% ± 4%	Explore
germinal center B cell	3 studies	55% ± 10%	Explore
IgM plasma cell	3 studies	39% ± 14%	Explore
pancreatic ductal cell	3 studies	62% ± 12%	Explore
ependymal cell	3 studies	45% ± 15%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	96% ± 3%	Explore
Schwann cell	3 studies	44% ± 11%	Explore
melanocyte	3 studies	54% ± 10%	Explore
granule cell	3 studies	28% ± 10%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	81% ± 10%	Explore
double-positive, alpha-beta thymocyte	3 studies	78% ± 5%	Explore
myoepithelial cell	3 studies	49% ± 12%	Explore
progenitor cell of mammary luminal epithelium	3 studies	59% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	21 studies	48% ± 17%	Explore
peripheral blood	21 studies	63% ± 20%	Explore
brain	19 studies	39% ± 20%	Explore
intestine	11 studies	47% ± 18%	Explore
kidney	10 studies	39% ± 12%	Explore
eye	10 studies	55% ± 17%	Explore
liver	7 studies	44% ± 18%	Explore
bone marrow	6 studies	45% ± 27%	Explore
lymph node	6 studies	53% ± 20%	Explore
placenta	5 studies	43% ± 20%	Explore
heart	5 studies	31% ± 5%	Explore
uterus	5 studies	61% ± 22%	Explore
adipose	5 studies	40% ± 16%	Explore
prostate	5 studies	50% ± 16%	Explore
breast	5 studies	51% ± 13%	Explore
pancreas	4 studies	58% ± 13%	Explore
esophagus	4 studies	50% ± 25%	Explore
skin	4 studies	34% ± 11%	Explore
adrenal gland	3 studies	43% ± 19%	Explore
stomach	3 studies	41% ± 30%	Explore
thymus	3 studies	63% ± 29%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	36832.67	245 / 245	100%	168.41	502 / 502
stomach	100%	23048.25	359 / 359	100%	67.30	286 / 286
uterus	100%	40502.59	170 / 170	100%	113.67	459 / 459
thymus	100%	49748.31	653 / 653	100%	165.63	604 / 605
lung	100%	29727.80	577 / 578	100%	92.22	1155 / 1155
breast	100%	37179.12	459 / 459	100%	115.66	1116 / 1118
intestine	100%	32476.21	966 / 966	100%	79.54	526 / 527
bladder	100%	26438.14	21 / 21	100%	102.37	503 / 504
skin	100%	30238.43	1809 / 1809	100%	93.59	471 / 472
adrenal gland	100%	26285.61	258 / 258	100%	111.56	229 / 230
liver	100%	15861.45	226 / 226	100%	66.60	404 / 406
esophagus	100%	30673.79	1445 / 1445	99%	66.95	182 / 183
kidney	100%	27210.60	89 / 89	99%	99.54	896 / 901
pancreas	99%	12854.23	326 / 328	100%	114.02	178 / 178
ovary	100%	45390.92	180 / 180	99%	75.24	427 / 430
brain	97%	19925.92	2569 / 2642	100%	133.01	705 / 705
adipose	100%	31429.99	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	134.65	29 / 29
spleen	100%	42445.37	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	97.03	45 / 45
ureter	0%	0	0 / 0	100%	165.08	1 / 1
blood vessel	100%	29399.38	1334 / 1335	0%	0	0 / 0
heart	98%	16383.81	847 / 861	0%	0	0 / 0
muscle	98%	13303.65	787 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	98%	87.22	78 / 80
peripheral blood	75%	9408.94	695 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	SRSF5
Protein name	Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5) Serine and arginine rich splicing factor 5 (cDNA FLJ57437, highly similar to Splicing factor, arginine/serine-rich 5) Serine and arginine rich splicing factor 5 (cDNA FLJ57379, highly similar to Splicing factor, arginine/serine-rich 5) Serine and arginine rich splicing factor 5 Alternative protein SRSF5
Synonyms	SRP40 HRS SFRS5
Description	FUNCTION: Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.
Accessions	ENST00000555547.5 ENST00000553548.5 L8E9M6 ENST00000553369.5 Q13243 B4DJK0 ENST00000554021.1 B4DUA4 ENST00000394366.6 [Q13243-1] G3V5K8 ENST00000557154.6 [Q13243-1] ENST00000555349.5 ENST00000553635.5 [Q13243-3] ENST00000553521.5 [Q13243-1]

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0006376	Biological process	mRNA splice site recognition
GO_0006397	Biological process	mRNA processing
GO_0016607	Cellular component	nuclear speck
GO_0005730	Cellular component	nucleolus
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

SRSF5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review