Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 13 studies | 26% ± 10% | |
| astrocyte | 8 studies | 33% ± 15% | |
| glutamatergic neuron | 6 studies | 42% ± 22% | |
| retinal cone cell | 6 studies | 27% ± 12% | |
| GABAergic neuron | 6 studies | 36% ± 17% | |
| macrophage | 6 studies | 23% ± 5% | |
| interneuron | 5 studies | 37% ± 21% | |
| microglial cell | 5 studies | 23% ± 5% | |
| epithelial cell | 5 studies | 33% ± 12% | |
| fibroblast | 5 studies | 21% ± 7% | |
| oligodendrocyte | 5 studies | 28% ± 8% | |
| adipocyte | 4 studies | 18% ± 3% | |
| oligodendrocyte precursor cell | 4 studies | 31% ± 9% | |
| endothelial cell of lymphatic vessel | 4 studies | 24% ± 5% | |
| hematopoietic precursor cell | 3 studies | 17% ± 1% | |
| neuron | 3 studies | 29% ± 8% | |
| myeloid cell | 3 studies | 17% ± 1% | |
| ciliated cell | 3 studies | 21% ± 4% | |
| lymphocyte | 3 studies | 23% ± 6% | |
| retinal rod cell | 3 studies | 17% ± 1% | |
| dendritic cell | 3 studies | 22% ± 6% | |
| abnormal cell | 3 studies | 23% ± 7% | |
| pericyte | 3 studies | 20% ± 5% | |
| goblet cell | 3 studies | 32% ± 19% | |
| transit amplifying cell | 3 studies | 34% ± 19% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 7 studies | 37% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2640.08 | 1445 / 1445 | 100% | 18.94 | 183 / 183 |
| lung | 100% | 2610.02 | 577 / 578 | 100% | 13.80 | 1153 / 1155 |
| brain | 100% | 1816.52 | 2635 / 2642 | 100% | 14.33 | 704 / 705 |
| thymus | 100% | 3029.38 | 653 / 653 | 100% | 13.79 | 602 / 605 |
| intestine | 100% | 2705.23 | 966 / 966 | 99% | 13.37 | 524 / 527 |
| prostate | 100% | 2519.42 | 245 / 245 | 99% | 14.04 | 499 / 502 |
| breast | 100% | 3170.57 | 459 / 459 | 99% | 20.14 | 1110 / 1118 |
| bladder | 100% | 3043.43 | 21 / 21 | 99% | 12.11 | 498 / 504 |
| ovary | 100% | 3039.98 | 180 / 180 | 99% | 10.71 | 424 / 430 |
| stomach | 100% | 2180.22 | 359 / 359 | 99% | 14.65 | 282 / 286 |
| pancreas | 100% | 1579.31 | 327 / 328 | 99% | 11.39 | 176 / 178 |
| uterus | 100% | 3138.25 | 170 / 170 | 98% | 13.65 | 452 / 459 |
| kidney | 100% | 1839.98 | 89 / 89 | 98% | 12.20 | 885 / 901 |
| skin | 100% | 3551.29 | 1809 / 1809 | 98% | 13.71 | 461 / 472 |
| adrenal gland | 100% | 2862.64 | 258 / 258 | 95% | 8.96 | 218 / 230 |
| liver | 100% | 1121.27 | 226 / 226 | 83% | 5.33 | 335 / 406 |
| adipose | 100% | 3021.63 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2606.61 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2907.65 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.67 | 1 / 1 |
| muscle | 99% | 1091.85 | 792 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 14.93 | 44 / 45 |
| heart | 97% | 1325.71 | 839 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 10.97 | 28 / 29 |
| eye | 0% | 0 | 0 / 0 | 91% | 7.72 | 73 / 80 |
| peripheral blood | 89% | 1869.63 | 827 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000398 | Biological process | mRNA splicing, via spliceosome |
| GO_0071013 | Cellular component | catalytic step 2 spliceosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0071007 | Cellular component | U2-type catalytic step 2 spliceosome |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0034458 | Molecular function | 3'-5' RNA helicase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003729 | Molecular function | mRNA binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0003727 | Molecular function | single-stranded RNA binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | AQR |
| Protein name | Aquarius homolog (Mouse), isoform CRA_a (Aquarius intron-binding spliceosomal factor) Alternative protein AQR RNA helicase aquarius (EC 3.6.4.13) (Intron-binding protein of 160 kDa) (IBP160) Aquarius intron-binding spliceosomal factor |
| Synonyms | KIAA0560 hCG_38784 |
| Description | FUNCTION: Involved in pre-mRNA splicing as component of the spliceosome . Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis . Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly . May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing . Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro) . . |
| Accessions | H0YH15 ENST00000543879.6 ENST00000156471.10 H0YLN9 ENST00000560117.1 O60306 L8E9N8 |