CWC22 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	7 studies	21% ± 6%	Explore
epithelial cell	4 studies	33% ± 8%	Explore
astrocyte	4 studies	25% ± 8%	Explore
oligodendrocyte	4 studies	22% ± 3%	Explore
hematopoietic precursor cell	3 studies	16% ± 1%	Explore
fibroblast	3 studies	18% ± 1%	Explore
GABAergic neuron	3 studies	38% ± 2%	Explore
glutamatergic neuron	3 studies	53% ± 5%	Explore
oligodendrocyte precursor cell	3 studies	24% ± 6%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	38% ± 9%	Explore
liver	3 studies	22% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1617.74	1445 / 1445	100%	32.06	183 / 183
lung	100%	1536.87	578 / 578	100%	29.74	1155 / 1155
breast	100%	1979.62	459 / 459	100%	30.89	1117 / 1118
ovary	100%	2187.64	180 / 180	100%	22.59	429 / 430
thymus	100%	1969.23	653 / 653	100%	32.85	603 / 605
brain	100%	1019.02	2629 / 2642	100%	25.62	705 / 705
pancreas	100%	757.17	328 / 328	99%	26.24	177 / 178
prostate	100%	1681.34	245 / 245	99%	24.41	499 / 502
uterus	100%	2249.78	170 / 170	99%	33.40	456 / 459
bladder	100%	1787.24	21 / 21	99%	24.90	497 / 504
stomach	100%	1215.28	359 / 359	98%	25.28	279 / 286
intestine	100%	1746.86	966 / 966	97%	26.26	512 / 527
adrenal gland	100%	1317.42	258 / 258	97%	16.95	223 / 230
kidney	100%	1229.75	89 / 89	97%	24.03	871 / 901
liver	100%	845.72	226 / 226	96%	14.95	389 / 406
skin	100%	1866.09	1809 / 1809	95%	27.49	447 / 472
blood vessel	100%	1947.05	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	28.04	29 / 29
muscle	100%	1239.00	803 / 803	0%	0	0 / 0
spleen	100%	1870.90	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	27.71	45 / 45
ureter	0%	0	0 / 0	100%	10.80	1 / 1
adipose	100%	1932.85	1203 / 1204	0%	0	0 / 0
heart	98%	898.84	848 / 861	0%	0	0 / 0
peripheral blood	84%	1139.67	782 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	75%	12.24	60 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0048024	Biological process	regulation of mRNA splicing, via spliceosome
GO_0016607	Cellular component	nuclear speck
GO_0071013	Cellular component	catalytic step 2 spliceosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0071007	Cellular component	U2-type catalytic step 2 spliceosome
GO_0005681	Cellular component	spliceosomal complex
GO_0071005	Cellular component	U2-type precatalytic spliceosome
GO_0071006	Cellular component	U2-type catalytic step 1 spliceosome
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

Gene name	CWC22
Protein name	Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb) Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog)
Synonyms	NCM KIAA1604
Description	FUNCTION: Required for pre-mRNA splicing as component of the spliceosome . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Promotes exon-junction complex (EJC) assembly . Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. .
Accessions	Q9HCG8 ENST00000410053.8 ENST00000404136.2 B7WP74

CWC22 report