RNPC3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
astrocyte	17 studies	38% ± 20%	Explore
oligodendrocyte	11 studies	31% ± 14%	Explore
oligodendrocyte precursor cell	10 studies	37% ± 15%	Explore
endothelial cell	10 studies	32% ± 13%	Explore
glutamatergic neuron	9 studies	51% ± 22%	Explore
microglial cell	9 studies	26% ± 9%	Explore
fibroblast	8 studies	22% ± 10%	Explore
ciliated cell	8 studies	20% ± 4%	Explore
adipocyte	8 studies	41% ± 12%	Explore
B cell	7 studies	17% ± 1%	Explore
GABAergic neuron	7 studies	46% ± 23%	Explore
amacrine cell	7 studies	40% ± 13%	Explore
natural killer cell	6 studies	17% ± 2%	Explore
interneuron	6 studies	43% ± 24%	Explore
retinal cone cell	6 studies	28% ± 9%	Explore
retinal rod cell	5 studies	25% ± 8%	Explore
retina horizontal cell	5 studies	25% ± 9%	Explore
cardiac muscle cell	5 studies	33% ± 12%	Explore
pericyte	5 studies	24% ± 10%	Explore
macrophage	5 studies	33% ± 9%	Explore
type II pneumocyte	5 studies	19% ± 4%	Explore
neuron	4 studies	34% ± 13%	Explore
retinal bipolar neuron	4 studies	22% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	51% ± 22%	Explore
epithelial cell	4 studies	34% ± 15%	Explore
Mueller cell	4 studies	27% ± 9%	Explore
basal cell	4 studies	32% ± 17%	Explore
myeloid cell	4 studies	19% ± 2%	Explore
club cell	4 studies	22% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	16% ± 1%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	20% ± 1%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	18% ± 3%	Explore
CD4-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	20% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	20% ± 3%	Explore
non-classical monocyte	3 studies	21% ± 5%	Explore
GABAergic interneuron	3 studies	30% ± 4%	Explore
retinal ganglion cell	3 studies	29% ± 8%	Explore
CD8-positive, alpha-beta T cell	3 studies	17% ± 1%	Explore
abnormal cell	3 studies	27% ± 7%	Explore
ependymal cell	3 studies	38% ± 16%	Explore
endothelial cell of lymphatic vessel	3 studies	24% ± 4%	Explore
monocyte	3 studies	20% ± 3%	Explore
lymphocyte	3 studies	20% ± 6%	Explore
smooth muscle cell	3 studies	24% ± 4%	Explore
T cell	3 studies	19% ± 3%	Explore
mast cell	3 studies	18% ± 2%	Explore
kidney loop of Henle epithelial cell	3 studies	30% ± 10%	Explore
renal principal cell	3 studies	27% ± 6%	Explore
mucosal invariant T cell	3 studies	16% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	15 studies	37% ± 18%	Explore
eye	8 studies	27% ± 13%	Explore
peripheral blood	4 studies	19% ± 3%	Explore
heart	3 studies	26% ± 3%	Explore
adipose	3 studies	28% ± 5%	Explore
kidney	3 studies	29% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	3097.26	180 / 180	100%	7.35	429 / 430
thymus	100%	4689.99	653 / 653	99%	8.46	600 / 605
esophagus	99%	1909.53	1433 / 1445	100%	5.07	183 / 183
lung	99%	2251.34	575 / 578	100%	5.65	1150 / 1155
breast	100%	2812.35	459 / 459	98%	5.43	1101 / 1118
intestine	100%	2317.09	965 / 966	98%	4.18	515 / 527
pancreas	100%	2236.51	327 / 328	98%	4.61	174 / 178
stomach	99%	1399.13	355 / 359	98%	4.43	279 / 286
uterus	100%	2890.50	170 / 170	96%	4.79	441 / 459
bladder	100%	2135.90	21 / 21	96%	3.99	484 / 504
kidney	100%	2180.02	89 / 89	96%	6.30	865 / 901
prostate	100%	2085.18	245 / 245	96%	4.08	481 / 502
skin	99%	1697.17	1796 / 1809	93%	4.32	438 / 472
brain	91%	1541.47	2414 / 2642	99%	6.05	700 / 705
adrenal gland	100%	1724.14	257 / 258	90%	3.07	208 / 230
liver	79%	602.72	179 / 226	77%	2.56	314 / 406
adipose	100%	2352.21	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	4.76	29 / 29
spleen	100%	1756.08	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	4.12	45 / 45
blood vessel	100%	2205.54	1333 / 1335	0%	0	0 / 0
muscle	100%	2124.61	800 / 803	0%	0	0 / 0
heart	94%	1581.38	807 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	83%	3.66	66 / 80
peripheral blood	53%	665.56	493 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0000398	Biological process	mRNA splicing, via spliceosome
GO_0008380	Biological process	RNA splicing
GO_0005654	Cellular component	nucleoplasm
GO_0005689	Cellular component	U12-type spliceosomal complex
GO_0005634	Cellular component	nucleus
GO_0030626	Molecular function	U12 snRNA binding
GO_0097157	Molecular function	pre-mRNA intronic binding

IV. Literature review

[source]

Gene name	RNPC3
Protein name	RNA-binding region-containing protein 3 (RNA-binding motif protein 40) (RNA-binding protein 40) (U11/U12 small nuclear ribonucleoprotein 65 kDa protein) (U11/U12 snRNP 65 kDa protein) (U11/U12-65K) RNA binding region (RNP1, RRM) containing 3 RNA-binding region-containing protein 3 (RNA-binding motif protein 40)
Synonyms	KIAA1839 SNRNP65 RBM40 RNP
Description	FUNCTION: Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA. . FUNCTION: Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA. .
Accessions	ENST00000423855.7 [Q96LT9-1] ENST00000533099.5 [Q96LT9-1] E9PPV2 H0YEB8 ENST00000527062.5 H0YE07 Q96LT9 ENST00000532117.1 ENST00000524641.1 ENST00000524631.5 [Q96LT9-2] X6RLP6 ENST00000531883.5

RNPC3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review