SNIP1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SNIP1 at tissue level.

III. Associated gene sets

GO_0000398Biological processmRNA splicing, via spliceosome
GO_0035196Biological processmiRNA processing
GO_0043124Biological processnegative regulation of canonical NF-kappaB signal transduction
GO_1903241Biological processU2-type prespliceosome assembly
GO_0005686Cellular componentU2 snRNP
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005681Cellular componentspliceosomal complex
GO_0071005Cellular componentU2-type precatalytic spliceosome
GO_0005634Cellular componentnucleus
GO_0140416Molecular functiontranscription regulator inhibitor activity
GO_0005515Molecular functionprotein binding
GO_0003729Molecular functionmRNA binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameSNIP1
Protein nameSmad nuclear interacting protein 1
Smad nuclear-interacting protein 1 (FHA domain-containing protein SNIP1)
Smad nuclear interacting protein 1 (cDNA, FLJ96650, Homo sapiens Smad nuclear interacting protein (SNIP1), mRNA)
SynonymshCG_25684
DescriptionFUNCTION: Required for pre-mRNA splicing as component of the spliceosome . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. .

AccessionsQ8TAD8
B1AK66
A0A1W2PRA0
ENST00000468040.2
ENST00000296215.8