GO_0070979 | protein K11-linked ubiquitination | OmnibusX

protein K11-linked ubiquitination

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	FZR1 UBE2L3 CDC27 AREL1 CDC16 ANAPC7 ANAPC16 UBE2W UBR5 UBE2A UBE2H UBE2D4 UBE2B CDC23 RNF4 ANAPC10 UBE2D3 UBE2E2 ANAPC1 UBE2E3 UBR4	dopaminergic neuron	5 studies
Group 2	UBE2S UBE2C ANAPC11 ANAPC5 ANAPC15 UBE2T	B cell hematopoietic stem cell lymphocyte epithelial cell	10 studies
Group 3	RNF26	epithelial cell neuron hematopoietic stem cell	4 studies
Group 4	CDC26 TRIM26 ANAPC13 RNF115	epithelial cell	6 studies
Group 5	PRKN ANAPC4	neuron epithelial cell glial cell	12 studies

II. Literature review

Name	protein K11-linked ubiquitination
ID	GO_0070979
collection_id	Biological process
Description	A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.
External URL
Genes	UBE2L5 RNF4 ANAPC4 ANAPC5 UBE2E3 UBE2C CDC27 PRKN UBE2W UBE2D3 UBE2A UBE2H ANAPC15 AREL1 RNF115 CDC26 UBE2D4 ANAPC10 ANAPC7 UBR4 UBR5 RNF26 ANAPC16 UBE2T CDC23 UBE2B ANAPC1 ANAPC11 UBE2E2 UBE2S TRIM26 FZR1 CDC16 ANAPC2 UBE2L3 ANAPC13