Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 12 studies | 33% ± 14% | |
endothelial cell | 11 studies | 25% ± 10% | |
astrocyte | 8 studies | 29% ± 11% | |
oligodendrocyte | 8 studies | 26% ± 8% | |
fibroblast | 7 studies | 19% ± 4% | |
macrophage | 6 studies | 22% ± 5% | |
oligodendrocyte precursor cell | 6 studies | 24% ± 9% | |
epithelial cell | 6 studies | 34% ± 13% | |
microglial cell | 5 studies | 22% ± 4% | |
type I pneumocyte | 5 studies | 19% ± 4% | |
neuron | 4 studies | 28% ± 9% | |
GABAergic neuron | 4 studies | 40% ± 15% | |
glutamatergic neuron | 4 studies | 50% ± 19% | |
endothelial cell of lymphatic vessel | 4 studies | 20% ± 2% | |
goblet cell | 4 studies | 25% ± 7% | |
interneuron | 4 studies | 33% ± 20% | |
basal cell | 3 studies | 33% ± 13% | |
transit amplifying cell | 3 studies | 31% ± 21% | |
adipocyte | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 4347.86 | 21 / 21 | 100% | 61.05 | 504 / 504 |
breast | 100% | 4385.12 | 459 / 459 | 100% | 67.50 | 1118 / 1118 |
esophagus | 100% | 3753.63 | 1445 / 1445 | 100% | 49.90 | 183 / 183 |
liver | 100% | 2885.00 | 226 / 226 | 100% | 34.50 | 406 / 406 |
lung | 100% | 4111.34 | 578 / 578 | 100% | 45.83 | 1155 / 1155 |
ovary | 100% | 4835.50 | 180 / 180 | 100% | 52.36 | 430 / 430 |
pancreas | 100% | 3013.69 | 328 / 328 | 100% | 51.73 | 178 / 178 |
prostate | 100% | 4756.67 | 245 / 245 | 100% | 56.53 | 502 / 502 |
skin | 100% | 4747.52 | 1809 / 1809 | 100% | 99.52 | 472 / 472 |
stomach | 100% | 3390.16 | 359 / 359 | 100% | 60.46 | 286 / 286 |
thymus | 100% | 4324.53 | 653 / 653 | 100% | 65.57 | 605 / 605 |
uterus | 100% | 5347.53 | 170 / 170 | 100% | 58.64 | 459 / 459 |
brain | 100% | 3272.16 | 2640 / 2642 | 100% | 54.76 | 705 / 705 |
kidney | 100% | 3485.27 | 89 / 89 | 100% | 52.25 | 900 / 901 |
intestine | 100% | 4122.64 | 966 / 966 | 100% | 63.70 | 526 / 527 |
adrenal gland | 100% | 3875.26 | 258 / 258 | 99% | 40.86 | 227 / 230 |
adipose | 100% | 4404.57 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 53.76 | 29 / 29 |
spleen | 100% | 5160.17 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 39.63 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 18.07 | 1 / 1 |
blood vessel | 100% | 3725.77 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2694.07 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 2471.23 | 856 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 46.19 | 78 / 80 |
peripheral blood | 87% | 1775.57 | 807 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0016567 | Biological process | protein ubiquitination |
GO_0031145 | Biological process | anaphase-promoting complex-dependent catabolic process |
GO_0070936 | Biological process | protein K48-linked ubiquitination |
GO_0070979 | Biological process | protein K11-linked ubiquitination |
GO_0051301 | Biological process | cell division |
GO_0051445 | Biological process | regulation of meiotic cell cycle |
GO_0007346 | Biological process | regulation of mitotic cell cycle |
GO_0045842 | Biological process | positive regulation of mitotic metaphase/anaphase transition |
GO_0005813 | Cellular component | centrosome |
GO_0005680 | Cellular component | anaphase-promoting complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0072686 | Cellular component | mitotic spindle |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
Gene name | CDC16 |
Protein name | CDC16 cell division cycle 16 homolog (S. cerevisiae), isoform CRA_d (cDNA FLJ56731, highly similar to Cell division cycle protein 16 homolog) Alternative protein CDC16 Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6) Cell division cycle 16 |
Synonyms | hCG_2011955 ANAPC6 |
Description | FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. . |
Accessions | B4DK74 ENST00000375308.5 [Q13042-4] ENST00000252458.6 ENST00000375310.5 [Q13042-4] ENST00000252457.9 [Q13042-2] A0A3B3ISD2 ENST00000356221.8 [Q13042-1] ENST00000628084.2 ENST00000650489.1 L8E7J3 Q5T8C6 Q13042 ENST00000360383.7 [Q13042-1] |