CDC16 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016567Biological processprotein ubiquitination
GO_0031145Biological processanaphase-promoting complex-dependent catabolic process
GO_0070936Biological processprotein K48-linked ubiquitination
GO_0070979Biological processprotein K11-linked ubiquitination
GO_0051301Biological processcell division
GO_0051445Biological processregulation of meiotic cell cycle
GO_0007346Biological processregulation of mitotic cell cycle
GO_0045842Biological processpositive regulation of mitotic metaphase/anaphase transition
GO_0005813Cellular componentcentrosome
GO_0005680Cellular componentanaphase-promoting complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0072686Cellular componentmitotic spindle
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCDC16
Protein nameCDC16 cell division cycle 16 homolog (S. cerevisiae), isoform CRA_d (cDNA FLJ56731, highly similar to Cell division cycle protein 16 homolog)
Alternative protein CDC16
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
Cell division cycle 16
SynonymshCG_2011955
ANAPC6
DescriptionFUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

AccessionsB4DK74
ENST00000375308.5 [Q13042-4]
ENST00000252458.6
ENST00000375310.5 [Q13042-4]
ENST00000252457.9 [Q13042-2]
A0A3B3ISD2
ENST00000356221.8 [Q13042-1]
ENST00000628084.2
ENST00000650489.1
L8E7J3
Q5T8C6
Q13042
ENST00000360383.7 [Q13042-1]