Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 23% ± 4% | |
| GABAergic neuron | 3 studies | 22% ± 3% | |
| glutamatergic neuron | 3 studies | 29% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 22% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1726.92 | 1445 / 1445 | 100% | 26.74 | 183 / 183 |
| ovary | 100% | 1663.17 | 180 / 180 | 100% | 25.73 | 430 / 430 |
| lung | 100% | 1365.68 | 577 / 578 | 100% | 24.10 | 1155 / 1155 |
| brain | 100% | 1217.52 | 2635 / 2642 | 100% | 28.44 | 705 / 705 |
| breast | 100% | 1703.95 | 459 / 459 | 100% | 32.80 | 1115 / 1118 |
| stomach | 100% | 1240.75 | 359 / 359 | 100% | 24.36 | 285 / 286 |
| intestine | 100% | 1721.33 | 966 / 966 | 100% | 24.12 | 525 / 527 |
| uterus | 100% | 1757.84 | 170 / 170 | 99% | 30.29 | 456 / 459 |
| prostate | 100% | 1505.76 | 245 / 245 | 99% | 23.11 | 498 / 502 |
| bladder | 100% | 1804.52 | 21 / 21 | 99% | 24.10 | 499 / 504 |
| skin | 100% | 2167.57 | 1809 / 1809 | 99% | 27.49 | 467 / 472 |
| thymus | 100% | 1570.68 | 653 / 653 | 99% | 22.70 | 598 / 605 |
| kidney | 100% | 1371.60 | 89 / 89 | 99% | 24.86 | 890 / 901 |
| pancreas | 100% | 774.82 | 327 / 328 | 98% | 19.48 | 175 / 178 |
| adrenal gland | 100% | 1441.83 | 258 / 258 | 96% | 19.15 | 221 / 230 |
| liver | 100% | 920.82 | 226 / 226 | 96% | 17.65 | 388 / 406 |
| adipose | 100% | 1575.03 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1472.53 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 26.08 | 29 / 29 |
| spleen | 100% | 1738.84 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 32.70 | 45 / 45 |
| muscle | 100% | 825.34 | 799 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 965.13 | 851 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 14.57 | 75 / 80 |
| peripheral blood | 72% | 1203.10 | 666 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0030071 | Biological process | regulation of mitotic metaphase/anaphase transition |
| GO_0070979 | Biological process | protein K11-linked ubiquitination |
| GO_0051445 | Biological process | regulation of meiotic cell cycle |
| GO_0000278 | Biological process | mitotic cell cycle |
| GO_0045842 | Biological process | positive regulation of mitotic metaphase/anaphase transition |
| GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
| GO_0007091 | Biological process | metaphase/anaphase transition of mitotic cell cycle |
| GO_0007096 | Biological process | regulation of exit from mitosis |
| GO_0051301 | Biological process | cell division |
| GO_0031145 | Biological process | anaphase-promoting complex-dependent catabolic process |
| GO_0070936 | Biological process | protein K48-linked ubiquitination |
| GO_0007346 | Biological process | regulation of mitotic cell cycle |
| GO_0007080 | Biological process | mitotic metaphase chromosome alignment |
| GO_0005680 | Cellular component | anaphase-promoting complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CDC23 |
| Protein name | Cell division cycle 23 Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8) |
| Synonyms | ANAPC8 |
| Description | FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. . |
| Accessions | Q9UJX2 H0Y936 ENST00000505120.1 ENST00000394884.7 [Q9UJX2-2] D6RBY8 ENST00000394886.7 [Q9UJX2-1] D6RCF8 ENST00000483961.6 ENST00000511383.5 |