Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 23 studies | 41% ± 21% | |
| fibroblast | 23 studies | 42% ± 20% | |
| pericyte | 23 studies | 37% ± 19% | |
| endothelial cell | 21 studies | 38% ± 17% | |
| smooth muscle cell | 18 studies | 36% ± 14% | |
| astrocyte | 18 studies | 40% ± 17% | |
| microglial cell | 17 studies | 68% ± 18% | |
| oligodendrocyte | 16 studies | 64% ± 18% | |
| oligodendrocyte precursor cell | 14 studies | 63% ± 17% | |
| B cell | 13 studies | 33% ± 15% | |
| glutamatergic neuron | 12 studies | 73% ± 20% | |
| GABAergic neuron | 11 studies | 59% ± 23% | |
| mesothelial cell | 11 studies | 42% ± 17% | |
| adipocyte | 11 studies | 73% ± 19% | |
| conventional dendritic cell | 10 studies | 26% ± 13% | |
| myeloid cell | 10 studies | 44% ± 21% | |
| plasmacytoid dendritic cell | 9 studies | 31% ± 13% | |
| neuron | 8 studies | 41% ± 18% | |
| epithelial cell | 8 studies | 39% ± 18% | |
| dendritic cell | 8 studies | 53% ± 13% | |
| endothelial cell of lymphatic vessel | 8 studies | 43% ± 15% | |
| myofibroblast cell | 7 studies | 32% ± 17% | |
| connective tissue cell | 7 studies | 27% ± 13% | |
| naive B cell | 7 studies | 22% ± 6% | |
| monocyte | 7 studies | 47% ± 25% | |
| non-classical monocyte | 6 studies | 23% ± 7% | |
| interneuron | 6 studies | 67% ± 19% | |
| retinal ganglion cell | 6 studies | 83% ± 12% | |
| amacrine cell | 6 studies | 47% ± 7% | |
| retinal cone cell | 6 studies | 54% ± 26% | |
| alveolar macrophage | 6 studies | 48% ± 28% | |
| type II pneumocyte | 6 studies | 42% ± 12% | |
| ciliated cell | 6 studies | 22% ± 5% | |
| plasma cell | 5 studies | 38% ± 12% | |
| retina horizontal cell | 5 studies | 46% ± 16% | |
| cardiac muscle cell | 5 studies | 63% ± 15% | |
| type I pneumocyte | 5 studies | 48% ± 8% | |
| basal cell | 5 studies | 34% ± 20% | |
| classical monocyte | 4 studies | 20% ± 2% | |
| glial cell | 4 studies | 35% ± 14% | |
| granule cell | 4 studies | 62% ± 15% | |
| immature B cell | 4 studies | 24% ± 5% | |
| retinal bipolar neuron | 4 studies | 34% ± 18% | |
| vein endothelial cell | 4 studies | 35% ± 20% | |
| Mueller cell | 4 studies | 27% ± 9% | |
| endothelial cell of vascular tree | 4 studies | 30% ± 14% | |
| muscle cell | 4 studies | 49% ± 20% | |
| hepatic stellate cell | 3 studies | 59% ± 17% | |
| renal alpha-intercalated cell | 3 studies | 32% ± 10% | |
| differentiation-committed oligodendrocyte precursor | 3 studies | 60% ± 10% | |
| GABAergic interneuron | 3 studies | 64% ± 5% | |
| precursor B cell | 3 studies | 23% ± 7% | |
| mononuclear phagocyte | 3 studies | 51% ± 11% | |
| GABAergic amacrine cell | 3 studies | 59% ± 7% | |
| OFF-bipolar cell | 3 studies | 60% ± 22% | |
| ON-bipolar cell | 3 studies | 54% ± 25% | |
| glycinergic amacrine cell | 3 studies | 54% ± 6% | |
| cholangiocyte | 3 studies | 46% ± 18% | |
| hepatocyte | 3 studies | 66% ± 21% | |
| retinal pigment epithelial cell | 3 studies | 33% ± 11% | |
| neural progenitor cell | 3 studies | 32% ± 10% | |
| ependymal cell | 3 studies | 32% ± 20% | |
| hematopoietic precursor cell | 3 studies | 22% ± 7% | |
| mast cell | 3 studies | 39% ± 15% | |
| adventitial cell | 3 studies | 35% ± 13% | |
| chondrocyte | 3 studies | 33% ± 12% | |
| club cell | 3 studies | 18% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 1427.18 | 180 / 180 | 100% | 52.45 | 428 / 430 |
| thymus | 100% | 1139.06 | 651 / 653 | 100% | 34.90 | 604 / 605 |
| brain | 99% | 1841.95 | 2628 / 2642 | 100% | 39.98 | 705 / 705 |
| prostate | 99% | 1398.05 | 242 / 245 | 100% | 39.75 | 502 / 502 |
| breast | 100% | 1687.63 | 459 / 459 | 98% | 23.97 | 1091 / 1118 |
| kidney | 100% | 1494.58 | 89 / 89 | 97% | 25.32 | 878 / 901 |
| lung | 100% | 1668.37 | 577 / 578 | 95% | 20.35 | 1103 / 1155 |
| uterus | 100% | 1580.20 | 170 / 170 | 92% | 24.20 | 423 / 459 |
| esophagus | 100% | 1729.45 | 1445 / 1445 | 92% | 17.07 | 168 / 183 |
| adrenal gland | 99% | 767.37 | 256 / 258 | 92% | 19.33 | 212 / 230 |
| liver | 100% | 695.31 | 226 / 226 | 83% | 12.24 | 339 / 406 |
| skin | 100% | 1439.61 | 1808 / 1809 | 82% | 15.65 | 388 / 472 |
| bladder | 100% | 1567.62 | 21 / 21 | 62% | 12.98 | 313 / 504 |
| stomach | 94% | 866.47 | 338 / 359 | 67% | 9.31 | 191 / 286 |
| pancreas | 67% | 282.89 | 221 / 328 | 91% | 17.74 | 162 / 178 |
| intestine | 90% | 1183.21 | 872 / 966 | 52% | 7.31 | 276 / 527 |
| adipose | 100% | 1989.50 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2623.99 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 29.69 | 29 / 29 |
| spleen | 100% | 1142.06 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 22.59 | 45 / 45 |
| muscle | 98% | 770.87 | 786 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 1071.83 | 835 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 84% | 10.09 | 67 / 80 |
| peripheral blood | 52% | 625.87 | 483 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1900087 | Biological process | positive regulation of G1/S transition of mitotic cell cycle |
| GO_0006974 | Biological process | DNA damage response |
| GO_0032020 | Biological process | ISG15-protein conjugation |
| GO_0070936 | Biological process | protein K48-linked ubiquitination |
| GO_0070979 | Biological process | protein K11-linked ubiquitination |
| GO_0070534 | Biological process | protein K63-linked ubiquitination |
| GO_0005634 | Cellular component | nucleus |
| GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
| GO_0061631 | Molecular function | ubiquitin conjugating enzyme activity |
| GO_0042296 | Molecular function | ISG15 transferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | UBE2E2 |
| Protein name | Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2) Alternative protein UBE2E2 Ubiquitin conjugating enzyme E2 E2 |
| Synonyms | UBCH8 |
| Description | FUNCTION: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein. . |
| Accessions | ENST00000452894.5 Q96LR5 ENST00000425792.5 L8E973 C9J180 F8W8F0 ENST00000335798.8 ENST00000396703.6 |