UBE2E2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1900087Biological processpositive regulation of G1/S transition of mitotic cell cycle
GO_0006974Biological processDNA damage response
GO_0032020Biological processISG15-protein conjugation
GO_0070936Biological processprotein K48-linked ubiquitination
GO_0070979Biological processprotein K11-linked ubiquitination
GO_0070534Biological processprotein K63-linked ubiquitination
GO_0005634Cellular componentnucleus
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0061631Molecular functionubiquitin conjugating enzyme activity
GO_0042296Molecular functionISG15 transferase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameUBE2E2
Protein nameUbiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Alternative protein UBE2E2
Ubiquitin conjugating enzyme E2 E2
SynonymsUBCH8
DescriptionFUNCTION: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein. .

AccessionsENST00000452894.5
Q96LR5
ENST00000425792.5
L8E973
C9J180
F8W8F0
ENST00000335798.8
ENST00000396703.6