ANAPC4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031145Biological processanaphase-promoting complex-dependent catabolic process
GO_0030071Biological processregulation of mitotic metaphase/anaphase transition
GO_0070936Biological processprotein K48-linked ubiquitination
GO_0070979Biological processprotein K11-linked ubiquitination
GO_0051301Biological processcell division
GO_0051445Biological processregulation of meiotic cell cycle
GO_0007346Biological processregulation of mitotic cell cycle
GO_0005680Cellular componentanaphase-promoting complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0034399Cellular componentnuclear periphery
GO_0005634Cellular componentnucleus
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0005515Molecular functionprotein binding
GO_0019903Molecular functionprotein phosphatase binding

IV. Literature review

[source]
Gene nameANAPC4
Protein nameAnaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)
Anaphase promoting complex subunit 4
SynonymsAPC4
DescriptionFUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

AccessionsENST00000510092.5 [Q9UJX5-3]
D6RAP6
ENST00000315368.8 [Q9UJX5-1]
Q9UJX5
ENST00000505080.1
ENST00000505991.1
D6RFM7