Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 10 studies | 34% ± 20% | |
oligodendrocyte | 6 studies | 23% ± 6% | |
endothelial cell | 4 studies | 24% ± 7% | |
epithelial cell | 4 studies | 37% ± 26% | |
astrocyte | 4 studies | 27% ± 6% | |
oligodendrocyte precursor cell | 4 studies | 25% ± 8% | |
macrophage | 4 studies | 19% ± 4% | |
microglial cell | 3 studies | 22% ± 4% | |
lymphocyte | 3 studies | 17% ± 2% | |
GABAergic neuron | 3 studies | 44% ± 4% | |
glutamatergic neuron | 3 studies | 50% ± 5% | |
endothelial cell of lymphatic vessel | 3 studies | 18% ± 2% | |
interneuron | 3 studies | 42% ± 22% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 41% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 2898.95 | 21 / 21 | 100% | 13.35 | 504 / 504 |
breast | 100% | 2254.68 | 459 / 459 | 100% | 12.28 | 1118 / 1118 |
esophagus | 100% | 1994.98 | 1445 / 1445 | 100% | 10.61 | 183 / 183 |
thymus | 100% | 2429.21 | 653 / 653 | 100% | 12.99 | 605 / 605 |
uterus | 100% | 3269.46 | 170 / 170 | 100% | 14.34 | 459 / 459 |
lung | 100% | 2113.22 | 577 / 578 | 100% | 11.81 | 1155 / 1155 |
prostate | 100% | 2875.79 | 245 / 245 | 100% | 9.34 | 501 / 502 |
kidney | 100% | 1973.30 | 89 / 89 | 100% | 10.29 | 899 / 901 |
liver | 100% | 1073.74 | 226 / 226 | 100% | 7.05 | 405 / 406 |
pancreas | 100% | 1376.78 | 327 / 328 | 100% | 11.33 | 178 / 178 |
brain | 100% | 1546.14 | 2633 / 2642 | 100% | 13.43 | 705 / 705 |
stomach | 100% | 1696.58 | 359 / 359 | 100% | 9.87 | 285 / 286 |
adrenal gland | 100% | 2287.03 | 258 / 258 | 100% | 8.66 | 229 / 230 |
ovary | 100% | 2888.03 | 180 / 180 | 99% | 7.82 | 427 / 430 |
intestine | 100% | 2355.68 | 966 / 966 | 99% | 10.37 | 522 / 527 |
skin | 100% | 1999.59 | 1809 / 1809 | 96% | 11.17 | 455 / 472 |
blood vessel | 100% | 2175.37 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 13.45 | 29 / 29 |
spleen | 100% | 3144.18 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 11.70 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.86 | 1 / 1 |
adipose | 100% | 2073.22 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 99% | 1128.17 | 794 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 1109.72 | 848 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 86% | 6.96 | 69 / 80 |
peripheral blood | 76% | 925.56 | 707 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0031145 | Biological process | anaphase-promoting complex-dependent catabolic process |
GO_0030071 | Biological process | regulation of mitotic metaphase/anaphase transition |
GO_0070936 | Biological process | protein K48-linked ubiquitination |
GO_0070979 | Biological process | protein K11-linked ubiquitination |
GO_0051301 | Biological process | cell division |
GO_0051445 | Biological process | regulation of meiotic cell cycle |
GO_0007346 | Biological process | regulation of mitotic cell cycle |
GO_0005680 | Cellular component | anaphase-promoting complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0034399 | Cellular component | nuclear periphery |
GO_0005634 | Cellular component | nucleus |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0019903 | Molecular function | protein phosphatase binding |
Gene name | ANAPC4 |
Protein name | Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4) Anaphase promoting complex subunit 4 |
Synonyms | APC4 |
Description | FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. . |
Accessions | ENST00000510092.5 [Q9UJX5-3] D6RAP6 ENST00000315368.8 [Q9UJX5-1] Q9UJX5 ENST00000505080.1 ENST00000505991.1 D6RFM7 |