CDC27 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016567Biological processprotein ubiquitination
GO_0007091Biological processmetaphase/anaphase transition of mitotic cell cycle
GO_0031145Biological processanaphase-promoting complex-dependent catabolic process
GO_0070936Biological processprotein K48-linked ubiquitination
GO_0070979Biological processprotein K11-linked ubiquitination
GO_0051301Biological processcell division
GO_0051445Biological processregulation of meiotic cell cycle
GO_0007346Biological processregulation of mitotic cell cycle
GO_0005813Cellular componentcentrosome
GO_0005680Cellular componentanaphase-promoting complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0072686Cellular componentmitotic spindle
GO_0005819Cellular componentspindle
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0019903Molecular functionprotein phosphatase binding

IV. Literature review

[source]
Gene nameCDC27
Protein nameCell division cycle protein 27 homolog
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Cell division cycle 27
Cell division cycle protein 27
SynonymsANAPC3
D17S978E
D0S1430E
hCG_1993274
DescriptionFUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

AccessionsP30260
E9PRZ6
I3L328
ENST00000570740.1
ENST00000573502.1
ENST00000575483.5
ENST00000531206.5 [P30260-2]
I3L1K3
I3L3Y5
ENST00000527547.5
I3L2Z8
ENST00000532893.5
I3L225
ENST00000573550.5
ENST00000533415.5
G5EA36
ENST00000571643.5
F6QPS0
ENST00000574304.5
I0EZ72
I3L394
ENST00000526866.5
I0EZ68
I3L3G1
ENST00000066544.8 [P30260-1]
ENST00000570818.5
K7EMA6
I3L3H6
ENST00000576484.1