ANAPC13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031145Biological processanaphase-promoting complex-dependent catabolic process
GO_0070936Biological processprotein K48-linked ubiquitination
GO_0070979Biological processprotein K11-linked ubiquitination
GO_0051301Biological processcell division
GO_0051445Biological processregulation of meiotic cell cycle
GO_0007346Biological processregulation of mitotic cell cycle
GO_0005680Cellular componentanaphase-promoting complex
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameANAPC13
Protein nameAnaphase-promoting complex subunit 13 (APC13) (Cyclosome subunit 13)
Anaphase-promoting complex subunit 13 (Cyclosome subunit 13)
SynonymshCG_1646826
DescriptionFUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

AccessionsENST00000514612.5
A8K3Z6
Q9BS18
ENST00000510994.5
ENST00000354910.10
ENST00000511751.1