ANAPC15 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031145Biological processanaphase-promoting complex-dependent catabolic process
GO_0070936Biological processprotein K48-linked ubiquitination
GO_0070979Biological processprotein K11-linked ubiquitination
GO_0051301Biological processcell division
GO_0051445Biological processregulation of meiotic cell cycle
GO_0090266Biological processregulation of mitotic cell cycle spindle assembly checkpoint
GO_0007346Biological processregulation of mitotic cell cycle
GO_0005680Cellular componentanaphase-promoting complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameANAPC15
Protein nameAnaphase-promoting complex subunit 15 (APC15)
Anaphase promoting complex subunit 15
Anaphase promoting complex subunit 15 (Chromosome 11 open reading frame 51, isoform CRA_c)
SynonymsC11orf51
hCG_23235
HSPC020
DescriptionFUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20. .

AccessionsENST00000535503.5 [P60006-1]
ENST00000545944.5 [P60006-1]
ENST00000539395.1
ENST00000543050.5
F5H3R3
ENST00000535234.5 [P60006-1]
ENST00000538117.5
ENST00000438939.6
F5GWM6
ENST00000502597.2
F5H6E4
F5GXB9
F5H2T3
F8WDQ6
ENST00000538919.5 [P60006-1]
ENST00000538393.5 [P60006-1]
ENST00000537644.5
ENST00000545680.5 [P60006-2]
ENST00000227618.9 [P60006-1]
ENST00000545333.5
G5EA39
ENST00000542531.5 [P60006-1]
ENST00000543587.5 [P60006-2]
P60006