CDC26 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	15 studies	21% ± 9%	Explore
CD4-positive, alpha-beta T cell	14 studies	20% ± 4%	Explore
regulatory T cell	13 studies	18% ± 3%	Explore
CD8-positive, alpha-beta T cell	12 studies	20% ± 5%	Explore
endothelial cell	12 studies	24% ± 9%	Explore
B cell	11 studies	18% ± 4%	Explore
natural killer cell	11 studies	20% ± 4%	Explore
T cell	10 studies	18% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	20% ± 4%	Explore
gamma-delta T cell	9 studies	24% ± 10%	Explore
basal cell	8 studies	26% ± 11%	Explore
ciliated cell	8 studies	32% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	19% ± 3%	Explore
mature NK T cell	8 studies	18% ± 2%	Explore
mucosal invariant T cell	7 studies	19% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	21% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	19% ± 2%	Explore
classical monocyte	6 studies	22% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	21% ± 4%	Explore
endothelial cell of vascular tree	6 studies	19% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	19% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	19% ± 2%	Explore
conventional dendritic cell	5 studies	28% ± 13%	Explore
memory B cell	5 studies	17% ± 1%	Explore
epithelial cell	5 studies	40% ± 15%	Explore
T follicular helper cell	5 studies	17% ± 1%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	17% ± 2%	Explore
naive B cell	4 studies	19% ± 2%	Explore
exhausted T cell	4 studies	19% ± 5%	Explore
non-classical monocyte	4 studies	25% ± 6%	Explore
innate lymphoid cell	4 studies	18% ± 1%	Explore
endothelial cell of lymphatic vessel	4 studies	21% ± 7%	Explore
plasmacytoid dendritic cell	4 studies	23% ± 4%	Explore
hematopoietic precursor cell	3 studies	26% ± 8%	Explore
endothelial cell of artery	3 studies	19% ± 3%	Explore
pericyte	3 studies	18% ± 3%	Explore
plasma cell	3 studies	28% ± 12%	Explore
club cell	3 studies	21% ± 4%	Explore
capillary endothelial cell	3 studies	16% ± 0%	Explore
vein endothelial cell	3 studies	16% ± 0%	Explore
dendritic cell	3 studies	32% ± 13%	Explore
goblet cell	3 studies	22% ± 6%	Explore
connective tissue cell	3 studies	22% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	9 studies	21% ± 5%	Explore
lung	6 studies	28% ± 8%	Explore
intestine	3 studies	24% ± 10%	Explore
liver	3 studies	27% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	316.77	1445 / 1445	100%	18.59	183 / 183
lung	100%	340.68	578 / 578	100%	22.20	1155 / 1155
ovary	100%	322.70	180 / 180	100%	24.72	430 / 430
stomach	100%	268.43	359 / 359	100%	21.12	286 / 286
brain	100%	227.74	2639 / 2642	100%	21.60	705 / 705
prostate	100%	353.14	245 / 245	100%	24.07	501 / 502
breast	100%	395.40	459 / 459	100%	23.01	1115 / 1118
pancreas	100%	160.57	327 / 328	100%	21.51	178 / 178
uterus	100%	321.11	170 / 170	100%	25.65	457 / 459
thymus	100%	363.32	652 / 653	100%	25.47	603 / 605
intestine	100%	355.98	966 / 966	99%	22.58	524 / 527
liver	100%	235.12	226 / 226	99%	16.57	403 / 406
bladder	100%	360.95	21 / 21	99%	22.03	498 / 504
skin	100%	359.90	1809 / 1809	99%	16.94	466 / 472
kidney	100%	364.24	89 / 89	98%	16.16	882 / 901
adrenal gland	100%	302.23	258 / 258	94%	17.15	217 / 230
adipose	100%	384.92	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	42.96	29 / 29
spleen	100%	380.15	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	22.86	45 / 45
ureter	0%	0	0 / 0	100%	9.62	1 / 1
blood vessel	100%	325.74	1334 / 1335	0%	0	0 / 0
muscle	100%	293.78	801 / 803	0%	0	0 / 0
heart	99%	298.04	854 / 861	0%	0	0 / 0
peripheral blood	99%	305.98	918 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	99%	17.27	79 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0031145	Biological process	anaphase-promoting complex-dependent catabolic process
GO_0070936	Biological process	protein K48-linked ubiquitination
GO_0070979	Biological process	protein K11-linked ubiquitination
GO_0051301	Biological process	cell division
GO_0051445	Biological process	regulation of meiotic cell cycle
GO_0007346	Biological process	regulation of mitotic cell cycle
GO_0005680	Cellular component	anaphase-promoting complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CDC26
Protein name	Anaphase-promoting complex subunit CDC26 (Anaphase-promoting complex subunit 12) (APC12) (Cell division cycle protein 26 homolog)
Synonyms	ANAPC12 C9orf17
Description	FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. .
Accessions	ENST00000374206.4 Q8NHZ8

CDC26 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review