Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 19 studies | 81% ± 20% | |
peripheral blood | 19 studies | 86% ± 17% | |
brain | 16 studies | 36% ± 19% | |
intestine | 13 studies | 90% ± 16% | |
eye | 10 studies | 71% ± 20% | |
kidney | 8 studies | 79% ± 21% | |
liver | 7 studies | 68% ± 26% | |
bone marrow | 7 studies | 72% ± 33% | |
pancreas | 5 studies | 83% ± 18% | |
uterus | 5 studies | 92% ± 12% | |
lymph node | 4 studies | 96% ± 3% | |
placenta | 4 studies | 87% ± 21% | |
heart | 4 studies | 47% ± 20% | |
adipose | 4 studies | 44% ± 27% | |
esophagus | 4 studies | 78% ± 24% | |
prostate | 4 studies | 90% ± 17% | |
breast | 4 studies | 88% ± 8% | |
skin | 3 studies | 78% ± 25% | |
stomach | 3 studies | 63% ± 24% | |
thymus | 3 studies | 80% ± 26% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 99335.94 | 1445 / 1445 | 100% | 934.33 | 183 / 183 |
ovary | 100% | 213691.74 | 180 / 180 | 100% | 1840.81 | 430 / 430 |
pancreas | 100% | 118386.49 | 328 / 328 | 100% | 1584.45 | 178 / 178 |
thymus | 100% | 89892.51 | 653 / 653 | 100% | 1941.87 | 605 / 605 |
uterus | 100% | 118190.43 | 170 / 170 | 100% | 1779.17 | 459 / 459 |
skin | 100% | 146749.34 | 1808 / 1809 | 100% | 1627.55 | 472 / 472 |
prostate | 100% | 114550.42 | 245 / 245 | 100% | 2998.56 | 501 / 502 |
stomach | 100% | 85845.28 | 359 / 359 | 100% | 1540.87 | 285 / 286 |
intestine | 100% | 100917.10 | 966 / 966 | 100% | 1960.57 | 525 / 527 |
breast | 100% | 120849.81 | 459 / 459 | 99% | 1583.55 | 1110 / 1118 |
liver | 100% | 45356.32 | 226 / 226 | 99% | 1072.46 | 403 / 406 |
bladder | 100% | 105879.19 | 21 / 21 | 99% | 1848.64 | 500 / 504 |
kidney | 100% | 72418.54 | 89 / 89 | 99% | 1107.48 | 893 / 901 |
lung | 100% | 78036.90 | 576 / 578 | 99% | 1328.32 | 1147 / 1155 |
adrenal gland | 100% | 104162.10 | 258 / 258 | 98% | 1134.94 | 226 / 230 |
brain | 99% | 36951.45 | 2604 / 2642 | 99% | 1090.50 | 701 / 705 |
adipose | 100% | 105569.64 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 3167.94 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 3771.56 | 29 / 29 |
spleen | 100% | 118368.61 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 1505.96 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 1279.80 | 1 / 1 |
blood vessel | 100% | 84371.66 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 67254.07 | 798 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 47379.76 | 842 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 97% | 84369.32 | 898 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006412 | Biological process | translation |
GO_0002181 | Biological process | cytoplasmic translation |
GO_0032496 | Biological process | response to lipopolysaccharide |
GO_0060425 | Biological process | lung morphogenesis |
GO_0042592 | Biological process | homeostatic process |
GO_1901194 | Biological process | negative regulation of formation of translation preinitiation complex |
GO_0017148 | Biological process | negative regulation of translation |
GO_0048246 | Biological process | macrophage chemotaxis |
GO_0071346 | Biological process | cellular response to type II interferon |
GO_0015934 | Cellular component | large ribosomal subunit |
GO_0005730 | Cellular component | nucleolus |
GO_0097452 | Cellular component | GAIT complex |
GO_0022626 | Cellular component | cytosolic ribosome |
GO_0005840 | Cellular component | ribosome |
GO_0016020 | Cellular component | membrane |
GO_0022625 | Cellular component | cytosolic large ribosomal subunit |
GO_0005925 | Cellular component | focal adhesion |
GO_0005829 | Cellular component | cytosol |
GO_0045202 | Cellular component | synapse |
GO_0005737 | Cellular component | cytoplasm |
GO_1990904 | Cellular component | ribonucleoprotein complex |
GO_0005634 | Cellular component | nucleus |
GO_0003729 | Molecular function | mRNA binding |
GO_0003735 | Molecular function | structural constituent of ribosome |
GO_0003723 | Molecular function | RNA binding |
Gene name | RPL13A |
Protein name | Ribosomal protein L13a Large ribosomal subunit protein uL13 (23 kDa highly basic protein) (60S ribosomal protein L13a) Large ribosomal subunit protein uL13 (60S ribosomal protein L13a) |
Synonyms | hCG_1998057 RPL13a |
Description | FUNCTION: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions . Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes . Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation . In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex . Involved in methylation of rRNA . . |
Accessions | Q9BSQ6 A0A096LPE0 Q0VGL3 M0QZU1 M0QYS1 ENST00000678713.1 A0A7I2V376 P40429 ENST00000621674.4 ENST00000391857.9 ENST00000624069.3 ENST00000679106.1 ENST00000484279.5 A0A7I2V5L3 ENST00000467825.2 A0A7I2V2L9 Q8J015 ENST00000678510.1 |