TPT1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	52 studies	91% ± 18%	Explore
endothelial cell	51 studies	77% ± 26%	Explore
macrophage	48 studies	84% ± 22%	Explore
natural killer cell	47 studies	90% ± 16%	Explore
T cell	44 studies	85% ± 22%	Explore
fibroblast	44 studies	83% ± 25%	Explore
CD8-positive, alpha-beta T cell	40 studies	89% ± 17%	Explore
pericyte	39 studies	79% ± 28%	Explore
CD4-positive, alpha-beta T cell	37 studies	93% ± 13%	Explore
smooth muscle cell	33 studies	76% ± 31%	Explore
plasmacytoid dendritic cell	33 studies	96% ± 5%	Explore
conventional dendritic cell	32 studies	97% ± 4%	Explore
dendritic cell	29 studies	91% ± 16%	Explore
mast cell	28 studies	79% ± 24%	Explore
plasma cell	28 studies	88% ± 18%	Explore
endothelial cell of lymphatic vessel	28 studies	82% ± 23%	Explore
classical monocyte	28 studies	94% ± 8%	Explore
monocyte	27 studies	87% ± 20%	Explore
regulatory T cell	27 studies	96% ± 9%	Explore
epithelial cell	27 studies	86% ± 24%	Explore
non-classical monocyte	26 studies	95% ± 9%	Explore
mature NK T cell	24 studies	89% ± 15%	Explore
basal cell	22 studies	89% ± 15%	Explore
gamma-delta T cell	21 studies	94% ± 10%	Explore
memory B cell	21 studies	97% ± 6%	Explore
connective tissue cell	20 studies	87% ± 19%	Explore
naive B cell	19 studies	97% ± 7%	Explore
ciliated cell	18 studies	82% ± 20%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	95% ± 11%	Explore
microglial cell	18 studies	57% ± 29%	Explore
mucosal invariant T cell	17 studies	94% ± 11%	Explore
capillary endothelial cell	17 studies	78% ± 20%	Explore
erythrocyte	16 studies	66% ± 27%	Explore
neutrophil	16 studies	78% ± 21%	Explore
endothelial cell of artery	16 studies	84% ± 16%	Explore
astrocyte	16 studies	41% ± 23%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	92% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	99% ± 1%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	92% ± 11%	Explore
myofibroblast cell	15 studies	91% ± 17%	Explore
vein endothelial cell	15 studies	84% ± 17%	Explore
myeloid cell	15 studies	80% ± 30%	Explore
mesothelial cell	14 studies	79% ± 27%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	95% ± 7%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	94% ± 11%	Explore
goblet cell	13 studies	81% ± 23%	Explore
endothelial cell of vascular tree	13 studies	88% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	88% ± 20%	Explore
innate lymphoid cell	12 studies	96% ± 5%	Explore
plasmablast	12 studies	96% ± 4%	Explore
secretory cell	12 studies	95% ± 7%	Explore
leukocyte	12 studies	86% ± 21%	Explore
type I pneumocyte	11 studies	75% ± 26%	Explore
progenitor cell	11 studies	85% ± 26%	Explore
type II pneumocyte	10 studies	83% ± 24%	Explore
T follicular helper cell	10 studies	98% ± 2%	Explore
club cell	10 studies	84% ± 25%	Explore
glutamatergic neuron	10 studies	34% ± 17%	Explore
IgG plasma cell	10 studies	88% ± 15%	Explore
hematopoietic stem cell	10 studies	89% ± 23%	Explore
platelet	9 studies	80% ± 13%	Explore
oligodendrocyte	9 studies	36% ± 13%	Explore
oligodendrocyte precursor cell	9 studies	37% ± 26%	Explore
abnormal cell	9 studies	92% ± 14%	Explore
neuron	9 studies	68% ± 19%	Explore
enterocyte	9 studies	79% ± 28%	Explore
IgA plasma cell	9 studies	85% ± 19%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	96% ± 8%	Explore
retinal rod cell	8 studies	56% ± 27%	Explore
alveolar macrophage	7 studies	81% ± 29%	Explore
ionocyte	7 studies	88% ± 8%	Explore
respiratory goblet cell	7 studies	87% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	7 studies	96% ± 6%	Explore
mononuclear phagocyte	7 studies	88% ± 17%	Explore
epithelial cell of proximal tubule	7 studies	92% ± 11%	Explore
retinal ganglion cell	7 studies	67% ± 28%	Explore
GABAergic neuron	7 studies	33% ± 9%	Explore
kidney loop of Henle epithelial cell	6 studies	82% ± 25%	Explore
renal alpha-intercalated cell	6 studies	98% ± 2%	Explore
enteroendocrine cell	6 studies	85% ± 18%	Explore
erythroblast	6 studies	81% ± 13%	Explore
transit amplifying cell	6 studies	84% ± 16%	Explore
amacrine cell	6 studies	57% ± 22%	Explore
retinal cone cell	6 studies	63% ± 30%	Explore
lymphocyte	6 studies	76% ± 34%	Explore
precursor B cell	6 studies	99% ± 2%	Explore
brush cell	6 studies	87% ± 12%	Explore
glial cell	6 studies	67% ± 27%	Explore
immature B cell	6 studies	99% ± 1%	Explore
adipocyte	6 studies	22% ± 6%	Explore
intermediate monocyte	6 studies	93% ± 10%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	98% ± 3%	Explore
granulocyte	6 studies	94% ± 9%	Explore
interneuron	6 studies	44% ± 24%	Explore
CD4-positive helper T cell	5 studies	95% ± 5%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	96% ± 6%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	91% ± 9%	Explore
hematopoietic precursor cell	5 studies	95% ± 7%	Explore
duct epithelial cell	5 studies	81% ± 32%	Explore
exhausted T cell	5 studies	96% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	97% ± 2%	Explore
megakaryocyte	5 studies	93% ± 6%	Explore
intestinal crypt stem cell	5 studies	83% ± 31%	Explore
OFF-bipolar cell	5 studies	57% ± 30%	Explore
ON-bipolar cell	5 studies	54% ± 30%	Explore
neuroendocrine cell	5 studies	96% ± 5%	Explore
T-helper 17 cell	5 studies	99% ± 1%	Explore
group 3 innate lymphoid cell	5 studies	99% ± 1%	Explore
retina horizontal cell	5 studies	55% ± 26%	Explore
mucus secreting cell	5 studies	82% ± 25%	Explore
Mueller cell	5 studies	62% ± 24%	Explore
double negative thymocyte	5 studies	99% ± 1%	Explore
hepatocyte	5 studies	81% ± 19%	Explore
melanocyte	5 studies	76% ± 23%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	79% ± 23%	Explore
deuterosomal cell	4 studies	83% ± 12%	Explore
precursor cell	4 studies	81% ± 29%	Explore
squamous epithelial cell	4 studies	81% ± 17%	Explore
cholangiocyte	4 studies	48% ± 30%	Explore
endothelial cell of sinusoid	4 studies	64% ± 25%	Explore
glomerular endothelial cell	4 studies	93% ± 5%	Explore
kidney connecting tubule epithelial cell	4 studies	94% ± 6%	Explore
podocyte	4 studies	90% ± 7%	Explore
retinal bipolar neuron	4 studies	62% ± 31%	Explore
glycinergic amacrine cell	4 studies	35% ± 16%	Explore
pro-B cell	4 studies	99% ± 1%	Explore
chondrocyte	4 studies	64% ± 24%	Explore
retinal pigment epithelial cell	4 studies	76% ± 22%	Explore
adventitial cell	4 studies	90% ± 13%	Explore
inflammatory macrophage	4 studies	88% ± 13%	Explore
muscle cell	4 studies	53% ± 22%	Explore
germinal center B cell	4 studies	95% ± 6%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	97% ± 5%	Explore
luminal cell of prostate epithelium	4 studies	83% ± 29%	Explore
IgM plasma cell	4 studies	88% ± 14%	Explore
T-helper 1 cell	4 studies	100% ± 0%	Explore
hillock cell	3 studies	70% ± 36%	Explore
pancreatic A cell	3 studies	94% ± 7%	Explore
type B pancreatic cell	3 studies	91% ± 11%	Explore
monocyte-derived dendritic cell	3 studies	100% ± 0%	Explore
hepatic stellate cell	3 studies	44% ± 22%	Explore
renal beta-intercalated cell	3 studies	98% ± 1%	Explore
neural crest cell	3 studies	99% ± 1%	Explore
paneth cell	3 studies	97% ± 4%	Explore
GABAergic amacrine cell	3 studies	44% ± 10%	Explore
renal principal cell	3 studies	92% ± 3%	Explore
thymocyte	3 studies	100% ± 0%	Explore
extravillous trophoblast	3 studies	100% ± 0%	Explore
placental villous trophoblast	3 studies	100% ± 0%	Explore
Schwann cell	3 studies	75% ± 33%	Explore
serous secreting cell	3 studies	91% ± 9%	Explore
tissue-resident macrophage	3 studies	81% ± 24%	Explore
follicular B cell	3 studies	90% ± 11%	Explore
intraepithelial lymphocyte	3 studies	96% ± 3%	Explore
rod bipolar cell	3 studies	68% ± 20%	Explore
acinar cell	3 studies	74% ± 32%	Explore
cardiac muscle cell	3 studies	34% ± 12%	Explore
myoepithelial cell	3 studies	98% ± 1%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	100% ± 0%	Explore
keratinocyte	3 studies	96% ± 4%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	99% ± 1%	Explore
double-positive, alpha-beta thymocyte	3 studies	99% ± 0%	Explore
progenitor cell of mammary luminal epithelium	3 studies	100% ± 0%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	21 studies	94% ± 8%	Explore
lung	20 studies	85% ± 18%	Explore
brain	17 studies	44% ± 23%	Explore
intestine	13 studies	90% ± 15%	Explore
eye	11 studies	62% ± 24%	Explore
kidney	9 studies	85% ± 20%	Explore
liver	8 studies	77% ± 21%	Explore
bone marrow	6 studies	86% ± 19%	Explore
lymph node	6 studies	98% ± 2%	Explore
placenta	5 studies	71% ± 36%	Explore
heart	5 studies	37% ± 17%	Explore
uterus	5 studies	94% ± 9%	Explore
prostate	5 studies	70% ± 37%	Explore
pancreas	4 studies	81% ± 24%	Explore
adipose	4 studies	55% ± 26%	Explore
esophagus	4 studies	72% ± 23%	Explore
breast	4 studies	97% ± 3%	Explore
adrenal gland	3 studies	80% ± 23%	Explore
skin	3 studies	83% ± 17%	Explore
stomach	3 studies	74% ± 11%	Explore
thymus	3 studies	86% ± 19%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	100138.05	21 / 21	100%	667.36	504 / 504
esophagus	100%	91983.05	1445 / 1445	100%	437.39	183 / 183
pancreas	100%	97454.20	328 / 328	100%	676.02	178 / 178
prostate	100%	96282.67	245 / 245	100%	767.45	502 / 502
stomach	100%	71409.93	359 / 359	100%	650.79	286 / 286
thymus	100%	84658.50	653 / 653	100%	964.92	605 / 605
uterus	100%	104341.50	170 / 170	100%	582.84	459 / 459
lung	100%	92471.68	577 / 578	100%	561.33	1155 / 1155
liver	100%	57343.35	226 / 226	100%	436.48	405 / 406
kidney	100%	107205.15	89 / 89	100%	740.99	898 / 901
intestine	100%	91527.17	966 / 966	100%	840.97	525 / 527
adrenal gland	100%	84479.39	258 / 258	100%	392.50	229 / 230
ovary	100%	163770.28	180 / 180	100%	540.04	428 / 430
breast	100%	111095.90	459 / 459	99%	553.33	1111 / 1118
skin	100%	89327.85	1807 / 1809	99%	502.21	467 / 472
brain	95%	38034.17	2510 / 2642	99%	359.17	700 / 705
adipose	100%	127064.42	1204 / 1204	0%	0	0 / 0
blood vessel	100%	95409.91	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	795.37	29 / 29
muscle	100%	276629.79	803 / 803	0%	0	0 / 0
spleen	100%	78388.05	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	380.34	45 / 45
ureter	0%	0	0 / 0	100%	263.73	1 / 1
eye	0%	0	0 / 0	99%	577.26	79 / 80
heart	98%	72568.93	846 / 861	0%	0	0 / 0
peripheral blood	88%	58496.48	815 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0009615	Biological process	response to virus
GO_0042981	Biological process	regulation of apoptotic process
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0006874	Biological process	intracellular calcium ion homeostasis
GO_0006816	Biological process	calcium ion transport
GO_1902230	Biological process	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO_0005615	Cellular component	extracellular space
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0005881	Cellular component	cytoplasmic microtubule
GO_0000922	Cellular component	spindle pole
GO_0005771	Cellular component	multivesicular body
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

Gene name	TPT1
Protein name	Translationally-controlled tumor protein (TCTP) (Fortilin) (Histamine-releasing factor) (HRF) (p23) Translationally-controlled tumor protein
Synonyms	hCG_32792
Description	FUNCTION: Involved in calcium binding and microtubule stabilization . Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein . .
Accessions	H0YCX0 ENST00000379056.5 [P13693-2] ENST00000616577.4 ENST00000379055.5 [P13693-2] ENST00000530705.6 [P13693-1] P13693 Q5W0H4 ENST00000530245.5 ENST00000379060.8 A0A0B4J2C3 J3KPG2 ENST00000528619.5 E9PJF7 ENST00000309246.9 ENST00000527226.2

TPT1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review